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Emily Freund
Emily Freund
Other namesEmily Crane
Verified email at gene.com
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Year
Condensin-driven remodelling of X chromosome topology during dosage compensation
E Crane, Q Bian, RP McCord, BR Lajoie, BS Wheeler, EJ Ralston, ...
Nature 523 (7559), 240-244, 2015
8342015
Transcriptional profiling of aging in human muscle reveals a common aging signature
JM Zahn, R Sonu, H Vogel, E Crane, K Mazan-Mamczarz, R Rabkin, ...
PLoS genetics 2 (7), e115, 2006
4562006
A transcriptional profile of aging in the human kidney
GEJ Rodwell, R Sonu, JM Zahn, J Lund, J Wilhelmy, L Wang, W Xiao, ...
PLoS biology 2 (12), e427, 2004
3962004
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
S Tahtinen, AJ Tong, P Himmels, J Oh, A Paler-Martinez, L Kim, ...
Nature immunology 23 (4), 532-542, 2022
2082022
Integration of innate immune signalling by caspase-8 cleavage of N4BP1
AD Gitlin, K Heger, AF Schubert, R Reja, D Yan, VC Pham, E Suto, ...
Nature 587 (7833), 275-280, 2020
722020
Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
EC Freund, JY Lock, J Oh, T Maculins, L Delamarre, CJ Bohlen, B Haley, ...
Journal of Experimental Medicine 217 (7), e20191692, 2020
642020
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing
EC Freund, AL Sapiro, Q Li, S Linder, JJ Moresco, JR Yates, JB Li
Cell Reports 31 (7), 2020
512020
Zinc finger RNA-binding protein Zn72D regulates ADAR-mediated RNA editing in neurons
AL Sapiro, EC Freund, L Restrepo, HH Qiao, A Bhate, Q Li, JQ Ni, ...
Cell reports 31 (7), 2020
262020
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines., 2022, 23
S Tahtinen, AJ Tong, P Himmels, J Oh, A Paler-Martinez, L Kim, ...
DOI: https://doi. org/10.1038/s41590-022-01160-y, 532-542, 0
5
HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features
WJ Thrift, NW Lounsbury, Q Broadwell, A Heidersbach, E Freund, ...
Biorxiv, 2022.12. 08.519673, 2022
22022
IL-1β and IL-1ra are key regulators of the inflammatory response to RNA vaccines
I Mellman, S Tahtinen, AJ Tong, P Himmels, J Oh, A Paler-Martinez, L Kim, ...
22021
The Nature of A:. A:.
E Crane, Q Bian, R Patton McCord, BR Lajoie, BS Wheeler, EJ Ralston, ...
22015
Optimized Nonviral Gene Disruption in Primary Murine and Human Myeloid Cells
EC Freund, SM Haag, B Haley, A Murthy
Dendritic Cells: Methods and Protocols, 201-217, 2023
12023
Comprehensive Impurity Profiling of mRNA: Evaluating Current Technologies and Advanced Analytical Techniques
J Camperi, S Lippold, L Ayalew, B Roper, S Shao, E Freund, ...
Analytical Chemistry, 2024
2024
Optimized tlr7 ligands and uses thereof
EC Freund, A Herzner, RA Leylek, T Ann-Jay, SM Wichner, LY Delamarre
US Patent App. 18/485,987, 2024
2024
Systematic perturbation screens decode regulators of inflammatory macrophage states and identify a role for TNF mRNA m6A modification
SM Haag, S Xie, C Eidenschenk, JP Fortin, M Callow, M Costa, A Lun, ...
bioRxiv, 2024.04. 12.589122, 2024
2024
Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage
AJ Tong, R Leylek, AM Herzner, D Rigas, S Wichner, C Blanchette, ...
Journal of Experimental Medicine 221 (2), e20230341, 2023
2023
1130 Design and characterization of novel TLR7-selective ligands with an automated screening platform
D Rigas, E Freund, R Leylek, AJ Tong, AM Herzner, SN Palace, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
Efficient genome editing in primary myeloid cells
AK Murthy, OH Jaehak, CJ Bohlen, EC Freund, BJ Haley, L Jaclyn
US Patent App. 17/822,746, 2023
2023
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JL Paulsen, F Leidner, DA Ragland, NK Yilmaz, CA Schiffer
J. Chem. Theory Comput 13, 2300-2309, 2017
2017
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