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Matthew D. Shortridge
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Comprehensive computational design of ordered peptide macrocycles
P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ...
Science 358 (6369), 1461-1466, 2017
1642017
Estimating protein− ligand binding affinity using high-throughput screening by NMR
MD Shortridge, DS Hage, GS Harbison, R Powers
Journal of combinatorial chemistry 10 (6), 948-958, 2008
1122008
Development of small molecules with a noncanonical binding mode to HIV-1 trans activation response (TAR) RNA
FA Abulwerdi, MD Shortridge, J Sztuba-Solinska, R Wilson, SFJ Le Grice, ...
Journal of medicinal chemistry 59 (24), 11148-11160, 2016
912016
Structure based approaches for targeting non-coding RNAs with small molecules
MD Shortridge, G Varani
Current opinion in structural biology 30, 79-88, 2015
762015
Analysis of metabolomic PCA data using tree diagrams
MT Werth, S Halouska, MD Shortridge, B Zhang, R Powers
Analytical biochemistry 399 (1), 58-63, 2010
742010
A macrocyclic peptide ligand binds the oncogenic MicroRNA-21 precursor and suppresses dicer processing
MD Shortridge, MJ Walker, T Pavelitz, Y Chen, W Yang, G Varani
ACS chemical biology 12 (6), 1611-1620, 2017
662017
An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb
MD Shortridge, PT Wille, AN Jones, A Davidson, J Bogdanovic, E Arts, ...
Nucleic acids research 47 (3), 1523-1531, 2019
432019
Bacterial protein structures reveal phylum dependent divergence
MD Shortridge, T Triplet, P Revesz, MA Griep, R Powers
Computational biology and chemistry 35 (1), 24-33, 2011
322011
PROFESS: A protein function, evolution, structure and sequence database
T Triplet, MD Shortridge, MA Griep, JL Stark, R Powers, P Revesz
Database 2010, baq011, 2010
272010
A multi-step NMR screen for the identification and evaluation of chemical leads for drug discovery
KA Mercier, MD Shortridge, R Powers
Combinatorial chemistry & high throughput screening 12 (3), 285-295, 2009
272009
Structure of the RNA specialized translation initiation element that recruits eIF3 to the 5′-UTR of c-Jun
MJ Walker, MD Shortridge, DD Albin, LY Cominsky, G Varani
Journal of molecular biology 432 (7), 1841-1855, 2020
182020
Structure and function of Pseudomonas aeruginosa protein PA1324 (21–170)
KA Mercier, JR Cort, MA Kennedy, EE Lockert, S Ni, MD Shortridge, ...
Protein Science 18 (3), 606-618, 2009
182009
Correlation between protein function and ligand binding profiles
MD Shortridge, M Bokemper, JC Copeland, JL Stark, R Powers
Journal of proteome research 10 (5), 2538-2545, 2011
152011
Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins
MD Shortridge, R Powers
PLoS One 4 (10), e7442, 2009
152009
Efficient NMR screening approach to discover small molecule fragments binding structured RNA
MD Shortridge, G Varani
Acs Medicinal Chemistry Letters 12 (8), 1253-1260, 2021
122021
Drug-like small molecules that inhibit expression of the oncogenic microRNA-21
MD Shortridge, B Chaubey, HJ Zhang, T Pavelitz, V Vidadala, C Tang, ...
ACS Chemical Biology 18 (2), 237-250, 2023
82023
A Small Cyclic β‐Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b
YT Sun, MD Shortridge, G Varani
ChemBioChem 20 (7), 931-939, 2019
72019
A slow dynamic RNA switch regulates processing of microRNA-21
MD Shortridge, GL Olsen, W Yang, MJ Walker, G Varani
Journal of molecular biology 434 (16), 167694, 2022
52022
PROFESS: a PROtein Function, Evolution
T Triplet, MD Shortridge, MA Griep, JL Stark, R Powers, P Revesz
Structure and Sequence database. Database 2010, 2010
42010
Identification of a Ligand-Binding Site on the Staphylococcus aureus DnaG Primase C-Terminal Domain
J Catazaro, J Periago, MD Shortridge, B Worley, A Kirchner, R Powers, ...
Biochemistry 56 (7), 932-943, 2017
32017
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Articles 1–20