| The human protein disulphide isomerase family: substrate interactions and functional properties L Ellgaard, LW Ruddock EMBO reports 6 (1), 28-32, 2005 | 874 | 2005 |
| Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation F Hatahet, LW Ruddock Antioxidants & redox signaling 11 (11), 2807-2850, 2009 | 714 | 2009 |
| The b′ domain provides the principal peptide‐binding site of protein disulfide isomerase but all domains contribute to binding of misfolded proteins P Klappa, LW Ruddock, NJ Darby, RB Freedman The EMBO journal, 1998 | 406 | 1998 |
| N-glycan processing in ER quality control LW Ruddock, M Molinari Journal of cell science 119 (21), 4373-4380, 2006 | 382 | 2006 |
| Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation C Reinhardt, ML von Brühl, D Manukyan, L Grahl, M Lorenz, B Altmann, ... The Journal of clinical investigation 118 (3), 1110-1122, 2008 | 380 | 2008 |
| Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation VD Nguyen, MJ Saaranen, AR Karala, AK Lappi, L Wang, IB Raykhel, ... Journal of molecular biology 406 (3), 503-515, 2011 | 318 | 2011 |
| A molecular specificity code for the three mammalian KDEL receptors I Raykhel, H Alanen, K Salo, J Jurvansuu, VD Nguyen, M Latva-Ranta, ... The Journal of cell biology 179 (6), 1193-1204, 2007 | 285 | 2007 |
| Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI+] of Saccharomyces cerevisiae SS Eaglestone, LW Ruddock, BS Cox, MF Tuite Proceedings of the National Academy of Sciences 97 (1), 240-244, 2000 | 243 | 2000 |
| Protein disulfide isomerases exploit synergy between catalytic and specific binding domains RB Freedman, P Klappa, LW Ruddock EMBO reports 3 (2), 136-140, 2002 | 229 | 2002 |
| EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation S Olivari, T Cali, KEH Salo, P Paganetti, LW Ruddock, M Molinari Biochemical and biophysical research communications 349 (4), 1278-1284, 2006 | 223 | 2006 |
| A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation S Olivari, C Galli, H Alanen, L Ruddock, M Molinari Journal of Biological Chemistry 280 (4), 2424-2428, 2005 | 211 | 2005 |
| A major fraction of endoplasmic reticulum-located glutathione is present as mixed disulfides with protein R Bass, LW Ruddock, P Klappa, RB Freedman Journal of Biological Chemistry 279 (7), 5257-5262, 2004 | 200 | 2004 |
| Substrate recognition by the protein disulfide isomerases F Hatahet, LW Ruddock The FEBS journal 274 (20), 5223-5234, 2007 | 195 | 2007 |
| Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase A Pirneskoski, P Klappa, M Lobell, RA Williamson, L Byrne, HI Alanen, ... Journal of Biological Chemistry 279 (11), 10374-10381, 2004 | 187 | 2004 |
| Pre-expression of a sulfhydryl oxidase significantly increases the yields of eukaryotic disulfide bond containing proteins expressed in the cytoplasm of E.coli VD Nguyen, F Hatahet, KEH Salo, E Enlund, C Zhang, LW Ruddock Microbial cell factories 10, 1-13, 2011 | 169 | 2011 |
| A conserved arginine plays a role in the catalytic cycle of the protein disulphide isomerases AK Lappi, MF Lensink, HI Alanen, KEH Salo, M Lobell, AH Juffer, ... Journal of molecular biology 335 (1), 283-295, 2004 | 159 | 2004 |
| Disruption of reducing pathways is not essential for efficient disulfide bond formation in the cytoplasm of E. coli F Hatahet, VD Nguyen, KEH Salo, LW Ruddock Microbial cell factories 9, 1-9, 2010 | 142 | 2010 |
| Insights into deglutathionylation reactions: Different intermediates in the glutaredoxin and protein disulfide isomerase catalyzed reactions are defined by the γ-linkage … MJ Peltoniemi, AR Karala, JK Jurvansuu, VL Kinnula, LW Ruddock Journal of biological chemistry 281 (44), 33107-33114, 2006 | 132 | 2006 |
| Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b’domain VD Nguyen, K Wallis, MJ Howard, AM Haapalainen, KEH Salo, ... Journal of molecular biology 383 (5), 1144-1155, 2008 | 131 | 2008 |
| The primary substrate binding site in the b′ domain of ERp57 is adapted for endoplasmic reticulum lectin association SJ Russell, LW Ruddock, KEH Salo, JD Oliver, QP Roebuck, ... Journal of Biological Chemistry 279 (18), 18861-18869, 2004 | 123 | 2004 |
