Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) K Yamagata, N Oda, PJ Kaisaki, S Menzel, H Furuta, M Vaxillaire, ... Nature 384 (6608), 455-458, 1996 | 2231 | 1996 |
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus Y Horikawa, N Oda, NJ Cox, X Li, M Orho-Melander, M Hara, Y Hinokio, ... Nature genetics 26 (2), 163-175, 2000 | 1966 | 2000 |
Mutation in hepatocyte nuclear factor–1β gene (TCF2) associated with MODY Y Horikawa, N Iwasaki, M Hara, H Furuta, Y Hinokio, BN Cockburn, ... Nature genetics 17 (4), 384-385, 1997 | 1153 | 1997 |
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus K Yasuda, K Miyake, Y Horikawa, K Hara, H Osawa, H Furuta, Y Hirota, ... Nature genetics 40 (9), 1092-1097, 2008 | 911 | 2008 |
A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2 CL Hanis, E Boerwinkle, R Chakraborty, DL Ellsworth, P Concannon, ... Nature genetics 13 (2), 161-166, 1996 | 828 | 1996 |
The Pro12→ Ala substitution in PPAR-γ is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin … H Mori, H Ikegami, Y Kawaguchi, S Seino, N Yokoi, J Takeda, I Inoue, ... Diabetes 50 (4), 891-894, 2001 | 357 | 2001 |
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility MN Weedon, PEH Schwarz, Y Horikawa, N Iwasaki, T Illig, R Holle, ... The American Journal of Human Genetics 73 (5), 1208-1212, 2003 | 234 | 2003 |
Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan Y Horikawa, K Miyake, K Yasuda, M Enya, Y Hirota, K Yamagata, ... The Journal of Clinical Endocrinology & Metabolism 93 (8), 3136-3141, 2008 | 176 | 2008 |
Organization and partial sequence of the hepatocyte nuclear factor-4α/MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY H Furuta, N Iwasaki, N Oda, Y Hinokio, Y Horikawa, K Yamagata, N Yano, ... Diabetes 46 (10), 1652-1657, 1997 | 176 | 1997 |
Mutations in the hepatocyte nuclear factor-1α/MODY3 gene in Japanese subjects with early-and late-onset NIDDM N Iwasaki, N Oda, M Ogata, M Hara, Y Hinokio, Y Oda, K Yamagata, ... Diabetes 46 (9), 1504-1508, 1997 | 141 | 1997 |
Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects K Miyake, Y Horikawa, K Hara, K Yasuda, H Osawa, H Furuta, Y Hirota, ... Journal of human genetics 53 (2), 174-180, 2008 | 137 | 2008 |
Impact of variants in the VEGF gene on progression of proliferative diabetic retinopathy S Nakamura, N Iwasaki, H Funatsu, S Kitano, Y Iwamoto Graefe's Archive for Clinical and Experimental Ophthalmology 247, 21-26, 2009 | 116 | 2009 |
Liver and kidney function in Japanese patients with maturity-onset diabetes of the young N Iwasaki, M Ogata, O Tomonaga, H Kuroki, T Kasahara, N Yano, ... Diabetes care 21 (12), 2144-2148, 1998 | 111 | 1998 |
Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function L Chen, M Takizawa, E Chen, A Schlessinger, J Segenthelar, JH Choi, ... Journal of Pharmacology and Experimental Therapeutics 335 (1), 42-50, 2010 | 110 | 2010 |
Increased plasma endothelin in NIDDM patients with retinopathy M Kawamura, H Ohgawara, M Naruse, N Suzuki, N Iwasaki, K Naruse, ... Diabetes care 15 (10), 1396-1397, 1992 | 99 | 1992 |
Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association K Miyake, W Yang, K Hara, K Yasuda, Y Horikawa, H Osawa, H Furuta, ... Journal of human genetics 54 (4), 236-241, 2009 | 94 | 2009 |
Splice site mutation in the hepatocyte nuclear factor-1β gene, IVS2nt+ 1G> A, associated with maturity-onset diabetes of the young, renal dysplasia and bicornuate uterus. N Iwasaki, I Okabe, MY Momoi, H Ohashi, M Ogata, Y Iwamoto Diabetologia 44 (3), 2001 | 74 | 2001 |
Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects N Iwasaki, NJ Cox, YQ Wang, PEH Schwarz, GI Bell, M Honda, M Imura, ... Diabetes 52 (1), 209-213, 2003 | 73 | 2003 |
Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus K Okamoto, N Iwasaki, C Nishimura, K Doi, E Noiri, S Nakamura, ... The American Journal of Human Genetics 86 (1), 54-64, 2010 | 69 | 2010 |
Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes K Okamoto, N Iwasaki, K Doi, E Noiri, Y Iwamoto, Y Uchigata, T Fujita, ... Diabetes 61 (7), 1734-1741, 2012 | 63 | 2012 |