| Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt Nature biotechnology 33 (2), 179-186, 2015 | 742 | 2015 |
| Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells R Chiarle, Y Zhang, RL Frock, SM Lewis, B Molinie, YJ Ho, DR Myers, ... Cell 147 (1), 107-119, 2011 | 500 | 2011 |
| A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation BR Johnson, RT Nitta, RL Frock, L Mounkes, DA Barbie, CL Stewart, ... Proceedings of the National Academy of Sciences 101 (26), 9677-9682, 2004 | 311 | 2004 |
| Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation RL Frock, BA Kudlow, AM Evans, SA Jameson, SD Hauschka, ... Genes & development 20 (4), 486-500, 2006 | 292 | 2006 |
| Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing J Hu, RM Meyers, J Dong, RA Panchakshari, FW Alt, RL Frock Nature protocols 11 (5), 853-871, 2016 | 219 | 2016 |
| Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila WM Deng, M Schneider, R Frock, C Castillejo-Lopez, EA Gaman, ... Oxford University Press for The Company of Biologists Limited 130 (1), 173-184, 2003 | 197 | 2003 |
| Chromosomal loop domains direct the recombination of antigen receptor genes J Hu, Y Zhang, L Zhao, RL Frock, Z Du, RM Meyers, F Meng, DG Schatz, ... Cell 163 (4), 947-959, 2015 | 155 | 2015 |
| Mechanism of tandem duplication formation in BRCA1-mutant cells NA Willis, RL Frock, F Menghi, EE Duffey, A Panday, V Camacho, ... Nature 551 (7682), 590-595, 2017 | 112 | 2017 |
| Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing BS Paulsen, PK Mandal, RL Frock, B Boyraz, R Yadav, S Upadhyayula, ... Nature biomedical engineering 1 (11), 878-888, 2017 | 100 | 2017 |
| Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ... Science translational medicine 13 (598), eabf2444, 2021 | 98 | 2021 |
| PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line V Kumar, FW Alt, RL Frock Proceedings of the National Academy of Sciences 113 (38), 10619-10624, 2016 | 94 | 2016 |
| A-type nuclear lamins, progerias and other degenerative disorders ED Smith, BA Kudlow, RL Frock, BK Kennedy Mechanisms of ageing and development 126 (4), 447-460, 2005 | 74 | 2005 |
| Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit DA Barbie, BA Kudlow, R Frock, J Zhao, BR Johnson, N Dyson, E Harlow, ... Molecular and cellular biology 24 (2), 595-607, 2004 | 47 | 2004 |
| Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development L Zhao, RL Frock, Z Du, J Hu, L Chen, MS Krangel, FW Alt Journal of Experimental Medicine 213 (9), 1921-1936, 2016 | 41 | 2016 |
| Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna−/− Mice RL Frock, SC Chen, DF Da, E Frett, C Lau, C Brown, DN Pak, Y Wang, ... Public Library of Science 7 (8), e42918, 2012 | 34 | 2012 |
| The use of molecular modeling and VSEPR theory in the undergraduate curriculum to predict the three-dimensional structure of molecules BW Pfennig, RL Frock Journal of chemical education 76 (7), 1018, 1999 | 33 | 1999 |
| Precise and broad scope genome editing based on high-specificity Cas9 nickases Q Wang, J Liu, JM Janssen, M Le Bouteiller, RL Frock, MAFV Gonçalves Nucleic acids research 49 (2), 1173-1198, 2021 | 31 | 2021 |
| Cell-extrinsic defective lymphocyte development in Lmna-/-mice JS Hale, RL Frock, SA Mamman, PJ Fink, BK Kennedy PLoS One 5 (4), e10127, 2010 | 31 | 2010 |
| Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking X Chen, F Tasca, Q Wang, J Liu, JM Janssen, MD Brescia, M Bellin, ... Nucleic Acids Research 48 (2), 974-995, 2020 | 30 | 2020 |
| Ku70 suppresses alternative end joining in G1-arrested progenitor B cells Z Liang, V Kumar, M Le Bouteiller, J Zurita, J Kenrick, SG Lin, J Lou, J Hu, ... Proceedings of the National Academy of Sciences 118 (21), e2103630118, 2021 | 22 | 2021 |
