| Structure of full-length Drosophila cryptochrome BD Zoltowski, AT Vaidya, D Top, J Widom, MW Young, BR Crane Nature 480 (7377), 396-399, 2011 | 195 | 2011 |
| Bovine lactoferricin causes apoptosis in Jurkat T-leukemia cells by sequential permeabilization of the cell membrane and targeting of mitochondria JS Mader, A Richardson, J Salsman, D Top, R de Antueno, R Duncan, ... Experimental cell research 313 (12), 2634-2650, 2007 | 135 | 2007 |
| Flavin reduction activates Drosophila cryptochrome AT Vaidya, D Top, CC Manahan, JM Tokuda, S Zhang, L Pollack, ... Proceedings of the National Academy of Sciences 110 (51), 20455-20460, 2013 | 131 | 2013 |
| Extensive syncytium formation mediated by the reovirus FAST proteins triggers apoptosis-induced membrane instability J Salsman, D Top, J Boutilier, R Duncan Journal of virology 79 (13), 8090-8100, 2005 | 127 | 2005 |
| Updated structure of Drosophila cryptochrome C Levy, BD Zoltowski, AR Jones, AT Vaidya, D Top, J Widom, MW Young, ... Nature 495 (7441), E3-E4, 2013 | 113 | 2013 |
| Coordination between differentially regulated circadian clocks generates rhythmic behavior D Top, MW Young Cold Spring Harbor Perspectives in Biology 10 (7), a033589, 2018 | 73 | 2018 |
| Circadian clock activity of cryptochrome relies on tryptophan-mediated photoreduction C Lin, D Top, CC Manahan, MW Young, BR Crane Proceedings of the National Academy of Sciences 115 (15), 3822-3827, 2018 | 72 | 2018 |
| Liposome reconstitution of a minimal protein‐mediated membrane fusion machine D Top, R de Antueno, J Salsman, J Corcoran, J Mader, D Hoskin, ... The EMBO journal 24 (17), 2980-2988, 2005 | 67 | 2005 |
| Myristoylation, a protruding loop, and structural plasticity are essential features of a nonenveloped virus fusion peptide motif JA Corcoran, R Syvitski, D Top, RM Epand, RF Epand, D Jakeman, ... Journal of Biological Chemistry 279 (49), 51386-51394, 2004 | 63 | 2004 |
| A virus-encoded cell–cell fusion machine dependent on surrogate adhesins J Salsman, D Top, C Barry, R Duncan PLoS pathogens 4 (3), e1000016, 2008 | 60 | 2008 |
| Changes in active site histidine hydrogen bonding trigger cryptochrome activation A Ganguly, CC Manahan, D Top, EF Yee, C Lin, MW Young, W Thiel, ... Proceedings of the National Academy of Sciences 113 (36), 10073-10078, 2016 | 56 | 2016 |
| GSK-3 and CK2 kinases converge on timeless to regulate the master clock D Top, E Harms, S Syed, EL Adams, L Saez Cell reports 16 (2), 357-367, 2016 | 56 | 2016 |
| Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome J Kummeling, DE Stremmelaar, N Raun, MRF Reijnders, MH Willemsen, ... Molecular psychiatry 26 (6), 2013-2024, 2021 | 52 | 2021 |
| Cell-cell membrane fusion induced by p15 fusion-associated small transmembrane (FAST) protein requires a novel fusion peptide motif containing a myristoylated polyproline type … D Top, JA Read, SJ Dawe, RT Syvitski, R Duncan Journal of Biological Chemistry 287 (5), 3403-3414, 2012 | 44 | 2012 |
| Enhanced Fusion Pore Expansion Mediated by the Trans-Acting Endodomain of the Reovirus FAST Proteins D Top, C Barry, T Racine, CL Ellis, R Duncan PLoS pathogens 5 (3), e1000331, 2009 | 36 | 2009 |
| Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network M Ahmad, W Li, D Top Journal of Biological Rhythms 36 (3), 203-220, 2021 | 27 | 2021 |
| CK1/Doubletime activity delays transcription activation in the circadian clock D Top, JL O'Neil, GE Merz, K Dusad, BR Crane, MW Young Elife 7, e32679, 2018 | 26 | 2018 |
| A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock A Giesecke, PS Johnstone, A Lamaze, J Landskron, E Atay, KF Chen, ... Current Biology 33 (2), 336-350. e5, 2023 | 9 | 2023 |
| The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder D Rots, TE Jakub, C Keung, A Jackson, S Banka, R Pfundt, BBA de Vries, ... The American Journal of Human Genetics 110 (6), 963-978, 2023 | 5 | 2023 |
| Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster PS Johnstone, M Ogueta, O Akay, I Top, S Syed, R Stanewsky, D Top Elife 11, e77029, 2022 | 4 | 2022 |
