| Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria L Griparic, NN Van Der Wel, IJ Orozco, PJ Peters, AM Van Der Bliek Journal of Biological Chemistry 279 (18), 18792-18798, 2004 | 555 | 2004 |
| FoxO1 target Gpr17 activates AgRP neurons to regulate food intake H Ren, IJ Orozco, Y Su, S Suyama, R Gutiérrez-Juárez, TL Horvath, ... Cell 149 (6), 1314-1326, 2012 | 184 | 2012 |
| A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism FL Fernandes-Rosa, G Daniil, IJ Orozco, C Göppner, R El Zein, V Jain, ... Nature genetics 50 (3), 355-361, 2018 | 181 | 2018 |
| Structures of human pannexin 1 reveal ion pathways and mechanism of gating Z Ruan, IJ Orozco, J Du, W Lü Nature 584 (7822), 646-651, 2020 | 149 | 2020 |
| A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment L Liu, IJ Orozco, E Planel, Y Wen, A Bretteville, P Krishnamurthy, L Wang, ... Neurobiology of disease 31 (1), 46-57, 2008 | 133 | 2008 |
| Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction MB Hoegg-Beiler, S Sirisi, IJ Orozco, I Ferrer, S Hohensee, M Auberson, ... Nature communications 5 (1), 3475, 2014 | 109 | 2014 |
| Preparation of oligomeric β-amyloid1-42 and induction of synaptic plasticity impairment on hippocampal slices M Fa, IJ Orozco, YI Francis, F Saeed, Y Gong, O Arancio JoVE (Journal of Visualized Experiments), e1884, 2010 | 88 | 2010 |
| Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease L Lee, E Dale, A Staniszewski, H Zhang, F Saeed, M Sakurai, M Fa', ... Scientific reports 4 (1), 7190, 2014 | 82 | 2014 |
| The poly (A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template IJ Orozco, SJ Kim, HG Martinson Journal of Biological Chemistry 277 (45), 42899-42911, 2002 | 66 | 2002 |
| Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer’s disease P Koppensteiner, F Trinchese, M Fà, D Puzzo, W Gulisano, S Yan, ... Scientific reports 6 (1), 32553, 2016 | 59 | 2016 |
| Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism C Göppner, IJ Orozco, MB Hoegg-Beiler, AH Soria, CA Hübner, ... Nature communications 10 (1), 4678, 2019 | 31 | 2019 |
| Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition Z Ruan, E Haley, IJ Orozco, M Sabat, R Myers, R Roth, J Du, W Lü Nature structural & molecular biology 28 (7), 604-613, 2021 | 30 | 2021 |
| The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice IJ Orozco, P Koppensteiner, I Ninan, O Arancio Molecular and Cellular Neuroscience 58, 76-84, 2014 | 27 | 2014 |
| KCNQ potassium channels modulate sensitivity of skin down-hair (D-hair) mechanoreceptors S Schütze, IJ Orozco, TJ Jentsch Journal of Biological Chemistry 291 (11), 5566-5575, 2016 | 24 | 2016 |
| Corrigendum: regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer’s disease L Lee, E Dale, A Staniszewski, H Zhang, F Saeed, M Sakurai, I Orozco, ... Scientific Reports 5, 2015 | 4 | 2015 |
| Ion pathways in the human pannexin 1 channel IJ Orozco, Z Ruan, J Du, W Lu Biophysical Journal 121 (3), 505a, 2022 | | 2022 |
| Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition ED Haley, Z Ruan, IJ Orozco, B Roth, M Sabat, R Myers, J Du, W Lu Biophysical Journal 121 (3), 14a, 2022 | | 2022 |
| Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition (vol 28, pg 604, 2021) Z Ruan, E Haley, IJ Orozco, M Sabat, R Myers, R Roth, J Du, W Lu NATURE STRUCTURAL & MOLECULAR BIOLOGY 28 (8), 702-702, 2021 | | 2021 |
| XErratum: FoxO1 target Gpr17 activates AgRP neurons to regulate food intake (Cell (2012) 149 (1314-1326)) H Ren, IJ Orozco, Y Su, S Suyama, R Gutiérrez-Juárez, TL Horvath, ... Cell 153 (5), X1166, 2013 | | 2013 |
| Poster# 125 ASSOCIATION OF HYPERPROLINEMIA WITH SCHIZOPHRENIA: IMPLICATIONS FOR THE ETIOLOGY, CLINICAL MANAGEMENT AND TREATMENT OF SCHIZOPHRENIA PATIENTS CL Clelland, V Drouet, I Orozco, A Kelly, A Kaon, L Liu, R Suckow, ... Schizophrenia Research, S136-S137, 2012 | | 2012 |
