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Ildem Akerman
Ildem Akerman
Associate Professor of Functional Genomics, University of Birmingham
Verified email at bham.ac.uk - Homepage
Title
Cited by
Cited by
Year
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ...
Nature genetics 46 (2), 136-143, 2014
5652014
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ...
Cell metabolism 16 (4), 435-448, 2012
4812012
GATA6 haploinsufficiency causes pancreatic agenesis in humans
HL Allen, SE Flanagan, C Shaw-Smith, E De Franco, I Akerman, ...
Nature genetics 44 (1), 20-22, 2012
3062012
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
3042019
Human pancreatic β cell lncRNAs control cell-specific regulatory networks
I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ...
Cell metabolism 25 (2), 400-411, 2017
2202017
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis
I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ...
Proceedings of the National Academy of Sciences 107 (7), 3105-3110, 2010
2182010
Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase
DA Dart, KE Adams, I Akerman, ND Lakin
Journal of Biological Chemistry 279 (16), 16433-16440, 2004
1712004
Argonaute2 mediates compensatory expansion of the pancreatic β cell
SG Tattikota, T Rathjen, SJ McAnulty, HH Wessels, I Akerman, ...
Cell metabolism 19 (1), 122-134, 2014
1652014
βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function
L Arnes, I Akerman, DA Balderes, J Ferrer, L Sussel
Genes & development 30 (5), 502-507, 2016
1262016
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
D Nasteska, NHF Fine, FB Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ...
Nature communications 12 (1), 674, 2021
662021
Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension
CSJ Westgate, HF Botfield, Z Alimajstorovic, A Yiangou, M Walsh, G Smith, ...
JCI insight 6 (10), 2021
512021
Metazoan DNA replication origins
O Ganier, P Prorok, I Akerman, M Méchali
Current opinion in cell biology 58, 134-141, 2019
462019
A predictable conserved DNA base composition signature defines human core DNA replication origins
I Akerman, B Kasaai, A Bazarova, PB Sang, I Peiffer, M Artufel, R Derelle, ...
Nature communications 11 (1), 4826, 2020
442020
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage
AL Medhurst, DO Warmerdam, I Akerman, EH Verwayen, R Kanaar, ...
Journal of cell science 121 (23), 3933-3940, 2008
422008
GATA believe it: new essential regulators of pancreas development
S Rodríguez-Seguí, I Akerman, J Ferrer
The Journal of clinical investigation 122 (10), 3469-3471, 2012
302012
Hepatic nuclear factor 1α (HNF1α) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes β-cells to endoplasmic reticulum stress
CL Kirkpatrick, A Wiederkehr, M Baquié, D Akhmedov, H Wang, ...
Journal of Biological Chemistry 286 (37), 32300-32312, 2011
282011
Vitamin-D-binding protein contributes to the maintenance of α cell function and glucagon secretion
K Viloria, D Nasteska, LJB Briant, S Heising, DP Larner, NHF Fine, ...
Cell Reports 31 (11), 2020
232020
Neonatal Diabetes International Group
I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ...
Johnstone K, Flanagan SE, Martinez R, Castano C, Patch AM, Fernandez-Rebollo …, 2010
202010
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens
L Schiffer, A Bossey, P Kempegowda, AE Taylor, I Akerman, ...
European Journal of Endocrinology 184 (3), 353-363, 2021
152021
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
F Fantuzzi, S Toivonen, AA Schiavo, H Chae, M Tariq, T Sawatani, ...
Frontiers in Cell and Developmental Biology 10, 967765, 2022
132022
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