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Sadhak Sengupta, Ph.D.
Sadhak Sengupta, Ph.D.
Triumvira Immunology Inc., USA
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Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor–modified T cells
S Kong, S Sengupta, B Tyler, AJ Bais, Q Ma, S Doucette, J Zhou, A Sahin, ...
Clinical Cancer Research 18 (21), 5949-5960, 2012
1782012
Significance of interleukin-13 receptor alpha 2–targeted glioblastoma therapy
B Thaci, CE Brown, E Binello, K Werbaneth, P Sampath, S Sengupta
Neuro-oncology 16 (10), 1304-1312, 2014
1642014
Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors
DA Wainwright, S Sengupta, Y Han, MS Lesniak
Neuro-oncology 13 (12), 1308-1323, 2011
1292011
Impact of temozolomide on immune response during malignant glioma chemotherapy
S Sengupta, J Marrinan, C Frishman, P Sampath
Journal of Immunology Research 2012, 2012
1252012
Mechanisms of immune evasion by gliomas
CE Rolle, S Sengupta, MS Lesniak
Glioma: Immunotherapeutic Approaches, 53-76, 2012
1162012
Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma
IV Balyasnikova, SD Ferguson, S Sengupta, Y Han, MS Lesniak
PloS one 5 (3), e9750, 2010
952010
Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model
AU Ahmed, CE Rolle, MA Tyler, Y Han, S Sengupta, DA Wainwright, ...
Molecular Therapy 18 (10), 1846-1856, 2010
842010
The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma
DA Wainwright, S Sengupta, Y Han, IV Ulasov, MS Lesniak
PloS one 5 (10), e15390, 2010
662010
Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model
S Sengupta, S Nandi, ES Hindi, DA Wainwright, Y Han, MS Lesniak
Neoplasia 12 (10), 837-847, 2010
632010
Challenges in clinical design of immunotherapy trials for malignant glioma
CE Rolle, S Sengupta, MS Lesniak
Neurosurgery Clinics 21 (1), 201-214, 2010
562010
Interleukin-13 receptor alpha 2-targeted glioblastoma immunotherapy
S Sengupta, B Thaci, AC Crawford, P Sampath
BioMed Research International 2014, 2014
512014
Glycogen synthase kinase 3 inhibition lowers PD-1 expression, promotes long-term survival and memory generation in antigen-specific CAR-T cells
S Sengupta, SC Katz, S Sengupta, P Sampath
Cancer Letters 433, 131-139, 2018
502018
Unrestrained glycogen synthase kinase-3β activity leads to activated T cell death and can be inhibited by natural adjuvant
S Sengupta, P Jayaraman, PM Chilton, CR Casella, TC Mitchell
The Journal of Immunology 178 (10), 6083-6091, 2007
322007
Chimeric antigen receptors for treatment of glioblastoma: a practical review of challenges and ways to overcome them
S Sengupta, G Mao, ZS Gokaslan, P Sampath
Cancer gene therapy 24 (3), 121-129, 2017
282017
Development of a function-blocking antibody against fibulin-3 as a targeted reagent for glioblastoma
MS Nandhu, P Behera, V Bhaskaran, SL Longo, LM Barrera-Arenas, ...
Clinical Cancer Research 24 (4), 821-833, 2018
272018
Enhanced transduction and replication of RGD-fiber modified adenovirus in primary T cells
S Sengupta, IV Ulasov, B Thaci, AU Ahmed, MS Lesniak
PLoS One 6 (3), e18091, 2011
232011
Adjuvant-induced survival signaling in clonally expanded T cells is associated with transient increases in pAkt levels and sustained uptake of glucose
S Sengupta, PM Chilton, TC Mitchell
Immunobiology 210 (9), 647-659, 2005
142005
Methods and compositions for treating cancer
P Sampath, S Sengupta, RP Junghans
US Patent 9,650,428, 2017
82017
Updates on chimeric antigen receptor-mediated glioblastoma immunotherapy
G Mao, P Sampath
Rhode Island Medical Journal 100 (6), 39, 2017
52017
Inhibition of GSK3beta leads to increased survival, proliferation and memory phenotype generation of GBM-specific CAR T cells (VAC5P. 1125)
S Sengupta, P Guha, S Katz, P Sampath
The Journal of Immunology 194 (1_Supplement), 73.10-73.10, 2015
42015
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Artículos 1–20