Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool P Reddy, L Liu, D Adhikari, K Jagarlamudi, S Rajareddy, Y Shen, C Du, ... Science 319 (5863), 611-613, 2008 | 714 | 2008 |
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 343 | 2015 |
Interspecies chimerism with mammalian pluripotent stem cells J Wu, A Platero-Luengo, M Sakurai, A Sugawara, MA Gil, T Yamauchi, ... Cell 168 (3), 473-486. e15, 2017 | 335 | 2017 |
In vivo amelioration of age-associated hallmarks by partial reprogramming A Ocampo, P Reddy, P Martinez-Redondo, A Platero-Luengo, F Hatanaka, ... Cell 167 (7), 1719-1733. e12, 2016 | 334 | 2016 |
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation HK Liao, F Hatanaka, T Araoka, P Reddy, MZ Wu, Y Sui, T Yamauchi, ... Cell 171 (7), 1495-1507. e15, 2017 | 260 | 2017 |
Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a L Liu, S Rajareddy, P Reddy, C Du, K Jagarlamudi, Y Shen, ... Development 134 (1), 199-209, 2007 | 227 | 2007 |
Control of mammalian oocyte growth and early follicular development by the oocyte PI3 kinase pathway: new roles for an old timer K Liu, S Rajareddy, L Liu, K Jagarlamudi, K Boman, G Selstam, P Reddy Developmental biology 299 (1), 1-11, 2006 | 208 | 2006 |
Selective elimination of mitochondrial mutations in the germline by genome editing P Reddy, A Ocampo, K Suzuki, J Luo, SR Bacman, SL Williams, ... Cell 161 (3), 459-469, 2015 | 207 | 2015 |
PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles P Reddy, D Adhikari, W Zheng, S Liang, T Hämäläinen, V Tohonen, ... Human molecular genetics 18 (15), 2813-2824, 2009 | 205 | 2009 |
Activation of Akt (PKB) and suppression of FKHRL1 in mouse and rat oocytes by stem cell factor during follicular activation and development P Reddy, L Shen, C Ren, K Boman, E Lundin, U Ottander, P Lindgren, ... Developmental biology 281 (2), 160-170, 2005 | 198 | 2005 |
Mechanisms maintaining the dormancy and survival of mammalian primordial follicles P Reddy, W Zheng, K Liu Trends in Endocrinology & Metabolism 21 (2), 96-103, 2010 | 196 | 2010 |
Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development L Kurian, A Aguirre, I Sancho-Martinez, C Benner, T Hishida, TB Nguyen, ... Circulation 131 (14), 1278-1290, 2015 | 167 | 2015 |
p27kip1 (Cyclin-Dependent Kinase Inhibitor 1B) Controls Ovarian Development by Suppressing Follicle Endowment and Activation and Promoting Follicle Atresia … S Rajareddy, P Reddy, C Du, L Liu, K Jagarlamudi, W Tang, Y Shen, ... Molecular endocrinology 21 (9), 2189-2202, 2007 | 140 | 2007 |
Formation of E-cadherin-mediated cell-cell adhesion activates AKT and mitogen activated protein kinase via phosphatidylinositol 3 kinase and ligand-independent activation of … P Reddy, L Liu, C Ren, P Lindgren, K Boman, Y Shen, E Lundin, ... Molecular Endocrinology 19 (10), 2564-2578, 2005 | 133 | 2005 |
Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation K Jagarlamudi, L Liu, D Adhikari, P Reddy, A Idahl, U Ottander, E Lundin, ... PloS one 4 (7), e6186, 2009 | 115 | 2009 |
Genetically modified mouse models for premature ovarian failure (POF) K Jagarlamudi, P Reddy, D Adhikari, K Liu Molecular and cellular endocrinology 315 (1-2), 1-10, 2010 | 72 | 2010 |
Actin cytoskeleton regulates Hippo signaling P Reddy, M Deguchi, Y Cheng, AJW Hsueh PloS one 8 (9), e73763, 2013 | 63 | 2013 |
Multi-functional norrin is a ligand for the LGR4 receptor C Deng, P Reddy, Y Cheng, CW Luo, CL Hsiao, AJW Hsueh Journal of cell science 126 (9), 2060-2068, 2013 | 63 | 2013 |
Single-dose CRISPR–Cas9 therapy extends lifespan of mice with Hutchinson–Gilford progeria syndrome E Beyret, HK Liao, M Yamamoto, R Hernandez-Benitez, Y Fu, G Erikson, ... Nature medicine 25 (3), 419-422, 2019 | 59 | 2019 |
Anti-aging strategies based on cellular reprogramming A Ocampo, P Reddy, JCI Belmonte Trends in molecular medicine 22 (8), 725-738, 2016 | 50 | 2016 |