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Maria Jesus  Almela
Maria Jesus Almela
Senior Scientist, GlaxoSmithKline
Verified email at gsk.com
Title
Cited by
Cited by
Year
Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence “transmission blocking” assay
J Lelièvre, MJ Almela, S Lozano, C Miguel, V Franco, D Leroy, E Herreros
PloS one 7 (4), e35019, 2012
1652012
Sordarins: In Vitro Activities of New Antifungal Derivatives against Pathogenic Yeasts, Pneumocystis carinii, and Filamentous Fungi
E Herreros, CM Martinez, MJ Almela, MS Marriott, FG De Las Heras, ...
Antimicrobial agents and chemotherapy 42 (11), 2863-2869, 1998
981998
Antifungal activities and cytotoxicity studies of six new azasordarins
E Herreros, MJ Almela, S Lozano, F Gomez De Las Heras, ...
Antimicrobial agents and chemotherapy 45 (11), 3132-3139, 2001
752001
A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery
EH Maria Jesus Almela, Sonia Lozano, Joël Lelièvre, Gonzalo Colmenarejo ...
PLOS ONE 10 (8), e0135139, 2015
592015
Inhibitors of poliovirus uncoating efficiently block the early membrane permeabilization induced by virus particles
MEGLC M. Jesús Almela
Journal of Virology 65 (5), 2572-7, 1991
411991
Cyclopropyl carboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen
LM Sanz, MB Jiménez-Díaz, B Crespo, C De-Cozar, MJ Almela, ...
Antimicrobial agents and chemotherapy 55 (12), 5740-5745, 2011
402011
Design, Synthesis, and in Vitro Activity of Novel 2′-O-Substituted 15-Membered Azalides
D Pešić, K Starčević, A Toplak, E Herreros, J Vidal, MJ Almela, D Jelić, ...
Journal of medicinal chemistry 55 (7), 3216-3227, 2012
332012
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites
AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ...
Journal of medicinal chemistry 62 (20), 9217-9235, 2019
302019
Transmission-blocking potential of MEFAS, a hybrid compound derived from artesunate and mefloquine
J Penna-Coutinho, MJ Almela, C Miguel-Blanco, E Herreros, PM Sá, ...
Antimicrobial Agents and Chemotherapy 60 (5), 3145-3147, 2016
202016
Red blood cells derived from peripheral blood and bone marrow CD34+ human haematopoietic stem cells are permissive to Plasmodium parasites infection
C Fernandez-Becerra, J Lelievre, M Ferrer, N Anton, R Thomson, ...
Memorias do Instituto Oswaldo Cruz 108, 801-803, 2013
162013
The discovery of novel antimalarial aminoxadiazoles as a promising nonendoperoxide scaffold
E Sandoval, MJ Lafuente-Monasterio, MJ Almela, P Castaneda, ...
Journal of medicinal chemistry 60 (16), 6880-6896, 2017
122017
Characterization of the phospholipidogenic potential of 4 (1H)-pyridone antimalarial derivatives
MJ Almela, PA Torres, S Lozano, E Herreros
Toxicology in vitro 23 (8), 1528-1534, 2009
102009
6–(3,4–dichlorophenoxy)–3–( thylthio)–2–pyridincarbonitrile inhibits poliovirus uncoating
MYLC M.Eugenia González, M. Jesús Almela
Antimicrobial Agents and Chemotherapy 34 (6), 1259-61, 1990
71990
A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents
N Bahamontes-Rosa, MG Gomez-Lorenzo, J Lelièvre, ...
Malaria Journal 15, 1-11, 2016
62016
Microplate assays for in vitro evaluation of anti-pneumocystis drugs
EMADGV E. Herreros, M.J. Almela, M. Martínez, S. Lozano, H. Jackson
Journal of Eukariotic Microbiology 44 (6), 43S-44S, 1997
5*1997
High-content phenotypic screen of a focused TCAMS drug library identifies novel disruptors of the malaria parasite calcium dynamics
W Chia, MG Gomez-Lorenzo, I Castellote, JX Tong, ...
ACS Chemical Biology 16 (11), 2348-2372, 2021
42021
Orobol: an inhibitor of vesicular stomatitis virus that blocks the synthesis of viral nucleic acids and the glycosylation of G protein
AILC M. J. Almela
Antiviral Chemistry & Chemotherapy 5 (2), 99-104, 1994
31994
In vitro absorption of 4 (1H)-pyridone antimalarial derivative and its pro-drug using a Caco-2 model
MJ Almela, PA Torres, S Lozano, JM Bueno, S Huss, JL Lavandera, ...
Toxicology Letters, S252, 2010
22010
In vitro antimalarial activity of 4 (1H)-pyridone derivatives
E Herreros, MJ Almela, S Lozano, MC Roncales, P Torres, J Gut, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 73 (6), 117-117, 2005
22005
Stage specific effects of antimalarial 4 (1H)-pyridones
E Herreros, MC Roncales, MJ Almela, S Lozano, P Torres, C Lopez, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 73 (6), 118-118, 2005
12005
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