| Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition V Limongelli, M Bonomi, L Marinelli, FL Gervasio, A Cavalli, E Novellino, ... Proceedings of the National Academy of Sciences 107 (12), 5411-5416, 2010 | 235 | 2010 |
| Docking Studies on αvβ3 Integrin Ligands: Pharmacophore Refinement and Implications for Drug Design L Marinelli, A Lavecchia, KE Gottschalk, E Novellino, H Kessler Journal of medicinal chemistry 46 (21), 4393-4404, 2003 | 167 | 2003 |
| The G‐Triplex DNA V Limongelli, S De Tito, L Cerofolini, M Fragai, B Pagano, R Trotta, ... Angewandte Chemie International Edition 52 (8), 2269-2273, 2013 | 162 | 2013 |
| Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic … R Ottanà, R Maccari, M Giglio, A Del Corso, M Cappiello, U Mura, ... European journal of medicinal chemistry 46 (7), 2797-2806, 2011 | 132 | 2011 |
| Characterizing the 1,4-Dihydropyridines Binding Interactions in the L-Type Ca2+ Channel: Model Construction and Docking Calculations S Cosconati, L Marinelli, A Lavecchia, E Novellino Journal of medicinal chemistry 50 (7), 1504-1513, 2007 | 127 | 2007 |
| Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action R Di Santo, R Costi, A Roux, M Artico, A Lavecchia, L Marinelli, ... Journal of medicinal chemistry 49 (6), 1939-1945, 2006 | 122 | 2006 |
| Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor. D Heckmann, A Meyer, L Marinelli, G Zahn, R Stragies, H Kessler ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46 (19), 3571-3574, 2007 | 120 | 2007 |
| Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle S Cosconati, L Marinelli, R Trotta, A Virno, S De Tito, R Romagnoli, ... Journal of the American Chemical Society 132 (18), 6425-6433, 2010 | 118 | 2010 |
| Sampling protein motion and solvent effect during ligand binding V Limongelli, L Marinelli, S Cosconati, C La Motta, S Sartini, L Mugnaini, ... Proceedings of the National Academy of Sciences 109 (5), 1467-1472, 2012 | 117 | 2012 |
| Imidazo[2,1-b]thiazole System: A Scaffold Endowing Dihydropyridines with Selective Cardiodepressant Activity R Budriesi, P Ioan, A Locatelli, S Cosconati, A Leoni, MP Ugenti, ... Journal of medicinal chemistry 51 (6), 1592-1600, 2008 | 107 | 2008 |
| Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4 O Demmer, I Dijkgraaf, U Schumacher, L Marinelli, S Cosconati, E Gourni, ... Journal of medicinal chemistry 54 (21), 7648-7662, 2011 | 106 | 2011 |
| Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells S Daniele, B Costa, E Zappelli, E Da Pozzo, S Sestito, G Nesi, ... Scientific reports 5 (1), 9956, 2015 | 104 | 2015 |
| Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders S Cosconati, L Marinelli, R Trotta, A Virno, L Mayol, E Novellino, AJ Olson, ... Journal of the American Chemical Society 131 (45), 16336-16337, 2009 | 104 | 2009 |
| Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch AO Frank, E Otto, C Mas-Moruno, HB Schiller, L Marinelli, S Cosconati, ... Angew. Chem. Int. Ed 49 (9278), e9281, 2010 | 98 | 2010 |
| Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a γδ-T lymphocytes-mediated activation mechanism D Simoni, N Gebbia, FP Invidiata, M Eleopra, P Marchetti, R Rondanin, ... Journal of medicinal chemistry 51 (21), 6800-6807, 2008 | 96 | 2008 |
| Ligand binding analysis for human α5β1 integrin: strategies for designing new α5β1 integrin antagonists L Marinelli, A Meyer, D Heckmann, A Lavecchia, E Novellino, H Kessler Journal of medicinal chemistry 48 (13), 4204-4207, 2005 | 94 | 2005 |
| Multiple N-methylation by a designed approach enhances receptor selectivity J Chatterjee, O Ovadia, G Zahn, L Marinelli, A Hoffman, C Gilon, ... Journal of medicinal chemistry 50 (24), 5878-5881, 2007 | 89 | 2007 |
| Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides JD Hegemann, M De Simone, M Zimmermann, TA Knappe, X Xie, ... Journal of Medicinal Chemistry 57 (13), 5829-5834, 2014 | 88 | 2014 |
| Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function VG D’Agostino, P Lal, B Mantelli, C Tiedje, C Zucal, N Thongon, ... Scientific reports 5 (1), 16478, 2015 | 83 | 2015 |
| N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential … E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ... Journal of medicinal chemistry 52 (15), 4757-4773, 2009 | 80 | 2009 |
