CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion JM Lee, EM Ramos, JH Lee, T Gillis, JS Mysore, MR Hayden, SC Warby, ... Neurology 78 (10), 690-695, 2012 | 421 | 2012 |
Identification of genetic factors that modify clinical onset of Huntington’s disease JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ... Cell 162 (3), 516-526, 2015 | 412 | 2015 |
Mitochondria and degenerative disorders M Orth, AHV Schapira American journal of medical genetics 106 (1), 27-36, 2001 | 359 | 2001 |
The cortical silent period: intrinsic variability and relation to the waveform of the transcranial magnetic stimulation pulse M Orth, JC Rothwell Clinical neurophysiology 115 (5), 1076-1082, 2004 | 320 | 2004 |
Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY) E van Duijn, D Craufurd, AAM Hubers, EJ Giltay, R Bonelli, H Rickards, ... Journal of Neurology, Neurosurgery & Psychiatry 85 (12), 1411-1418, 2014 | 305 | 2014 |
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study DJH Moss, AF Pardiñas, D Langbehn, K Lo, BR Leavitt, R Roos, A Durr, ... The Lancet Neurology 16 (9), 701-711, 2017 | 289 | 2017 |
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 276 | 2019 |
Observing Huntington's disease: the European Huntington's disease network's REGISTRY M Orth, European Huntington's Disease Network Journal of Neurology, Neurosurgery & Psychiatry 82 (12), 1409-1412, 2011 | 273 | 2011 |
Expression of mutant α-synuclein causes increased susceptibility to dopamine toxicity SJ Tabrizi, M Orth, JM Wilkinson, JW Taanman, TT Warner, JM Cooper, ... Human molecular genetics 9 (18), 2683-2689, 2000 | 253 | 2000 |
Mitochondrial involvement in Parkinson’s disease M Orth, AHV Schapira Neurochemistry international 40 (6), 533-541, 2002 | 247 | 2002 |
The variability of intracortical inhibition and facilitation M Orth, AH Snijders, JC Rothwell Clinical neurophysiology 114 (12), 2362-2369, 2003 | 243 | 2003 |
Motor inhibition in patients with Gilles de la Tourette syndrome: functional activation patterns as revealed by EEG coherence DJ Serrien, M Orth, AH Evans, AJ Lees, P Brown Brain 128 (1), 116-125, 2005 | 220 | 2005 |
The Gilles de la Tourette syndrome–Quality of Life Scale (GTS-QOL) development and validation AE Cavanna, A Schrag, D Morley, M Orth, MM Robertson, E Joyce, ... Neurology 71 (18), 1410-1416, 2008 | 217 | 2008 |
Multispectral brain morphometry in Tourette syndrome persisting into adulthood B Draganski, D Martino, AE Cavanna, C Hutton, M Orth, MM Robertson, ... Brain 133 (12), 3661-3675, 2010 | 167 | 2010 |
Structural changes in the somatosensory system correlate with tic severity in Gilles de la Tourette syndrome G Thomalla, HR Siebner, M Jonas, T Bäumer, K Biermann-Ruben, ... Brain 132 (3), 765-777, 2009 | 167 | 2009 |
An exploratory double‐blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with H untington's disease SD Süssmuth, S Haider, GB Landwehrmeyer, R Farmer, C Frost, ... British journal of clinical pharmacology 79 (3), 465-476, 2015 | 164 | 2015 |
Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders A Berardelli, G Abbruzzese, R Chen, M Orth, MC Ridding, C Stinear, ... Brain stimulation 1 (3), 183-191, 2008 | 154 | 2008 |
Primary focal dystonia: evidence for distinct neuropsychiatric and personality profiles R Lencer, S Steinlechner, J Stahlberg, H Rehling, M Orth, T Baeumer, ... Journal of Neurology, Neurosurgery & Psychiatry 80 (10), 1176-1179, 2009 | 152 | 2009 |
Excitability of motor cortex inhibitory circuits in Tourette syndrome before and after single dose nicotine M Orth, B Amann, MM Robertson, JC Rothwell Brain 128 (6), 1292-1300, 2005 | 149 | 2005 |
The HTT CAG-expansion mutation determines age at death but not disease duration in Huntington disease JW Keum, A Shin, T Gillis, JS Mysore, KA Elneel, D Lucente, T Hadzi, ... The American Journal of Human Genetics 98 (2), 287-298, 2016 | 148 | 2016 |