Thomas Evangelidis
Thomas Evangelidis
Institute of Organic Chemistry and Biochemistry, Prague, CZ
Verified email at uochb.cas.cz - Homepage
Title
Cited by
Cited by
Year
Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir
L Xie, T Evangelidis, L Xie, PE Bourne
PLoS computational biology 7 (4), e1002037, 2011
1732011
Investigating the Structure and Dynamics of the PIK3CA Wild-Type and H1047R Oncogenic Mutant
P Gkeka, T Evangelidis, M Pavlaki, V Lazani, S Christoforidis, B Agianian, ...
PLoS computational biology 10 (10), e1003895, 2014
672014
De novo design of a non-local β-sheet protein with high stability and accuracy
E Marcos, TM Chidyausiku, AC McShan, T Evangelidis, S Nerli, L Carter, ...
Nature structural & molecular biology 25 (11), 1028-1034, 2018
552018
Origin, diversification and substrate specificity in the family of NCS 1/FUR transporters
E Krypotou, T Evangelidis, J Bobonis, AA Pittis, T Gabaldón, ...
Molecular microbiology 96 (5), 927-950, 2015
512015
Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA
E Krypotou, G Lambrinidis, T Evangelidis, E Mikros, G Diallinas
Molecular microbiology 93 (1), 129-145, 2014
302014
Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra
T Evangelidis, S Nerli, J Nováček, AE Brereton, PA Karplus, RR Dotas, ...
Nature communications 9 (1), 1-13, 2018
262018
The Aspergillus nidulans proline permease as a model for understanding the factors determining substrate binding and specificity of fungal amino acid transporters
C Gournas, T Evangelidis, A Athanasopoulos, E Mikros, ...
Journal of Biological Chemistry 290 (10), 6141-6155, 2015
192015
Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli
M Botou, P Lazou, K Papakostas, G Lambrinidis, T Evangelidis, E Mikros, ...
Molecular microbiology 108 (2), 204-219, 2018
132018
An integrated workflow for proteome-wide off-target identification and polypharmacology drug design
T Evangelidis, L Xie
Tsinghua Science and Technology 19 (3), 275-284, 2014
52014
Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
K Yperman, AC Papageorgiou, R Merceron, S De Munck, Y Bloch, ...
Nature communications 12 (1), 1-11, 2021
32021
Discovery of new aminosubstituted pyrrolopyrimidines with antiproliferative activity against breast cancer cells and investigation of their effect towards the PI3Kα enzyme
K Daniilides, N Lougiakis, T Evangelidis, IK Kostakis, N Pouli, P Marakos, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2017
32017
Structural studies of the oncoproteins c-Myc and PI3Kα and development of new synthetic molecules inhibiting their function
T Evangelidis
Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Σχολή Επιστημών Υγείας …, 2017
2017
Structure-function analysis of the different selectivity preferences of pyrimidine and/or purine transporters in the Nucleobase: Cation Symporter-2 (NCS2) family: P32-001-SH
M Botou, K Papakostas, T Evangelidis, E Mikros, S Frillingos
The Febs Journal 282, 2015
2015
The Aspergillus nidulans Proline Permease as a Model for Understanding the Factors Determining Substrate Binding and Specificity of Fungal Amino Acid Transporters
T Evangelidis, A Athanasopoulos, E Mikros, V Sophianopoulou
2015
Substrate binding and specificity of fungal aa transporters
C Gournas, T Evangelidis, A Athanasopoulos, E Mikros, ...
regulation 12, 14, 2015
2015
Allosteric Modulation of WT and H1047R Mutant PI3Kα Investigated by MD Simulations
P Gkeka, T Evangelidis, Z Cournia
Biophysical Journal 104 (2), 402a, 2013
2013
MD simulations of the PI3K alpha wild type and mutant forms: Implications for drug design
T Evangelidis, P Gkeka, Z Cournia
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012
2012
Homology Modeling and Molecular Dynamics Simulations of the Human Wild Type and H1047R Mutant Form of the Catalytic Subunit of PI3K
T Evangelidis, P Gkeka, Z Cournia
Fast Methods for Long-Range Interactions in Complex Systems, 7, 2011
2011
Comparison of the Charge Distribution of Protein Molecules via Multipole Parameterizations
A Gramada, T Evangelidis, PE Bourne
Biophysical Journal 100 (3), 320a, 2011
2011
Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the
L Xie, T Evangelidis, L Xie, PE Bourne
2011
The system can't perform the operation now. Try again later.
Articles 1–20