An HIF-1α/VEGF-A axis in cytotoxic T cells regulates tumor progression A Palazon, PA Tyrakis, D Macias, P Veliça, H Rundqvist, S Fitzpatrick, ... Cancer cell 32 (5), 669-683. e5, 2017 | 406 | 2017 |
S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate PA Tyrakis, A Palazon, D Macias, KL Lee, AT Phan, P Veliça, J You, ... Nature 540 (7632), 236-241, 2016 | 352 | 2016 |
Remodeling of bone marrow hematopoietic stem cell niches promotes myeloid cell expansion during premature or physiological aging YH Ho, R Del Toro, J Rivera-Torres, J Rak, C Korn, A García-García, ... Cell stem cell 25 (3), 407-418. e6, 2019 | 233 | 2019 |
HIF2α–arginase axis is essential for the development of pulmonary hypertension AS Cowburn, A Crosby, D Macias, C Branco, RDDR Colaço, ... Proceedings of the National Academy of Sciences 113 (31), 8801-8806, 2016 | 169 | 2016 |
Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity E González‐Gualda, M Pàez‐Ribes, B Lozano‐Torres, D Macias, ... Aging cell 19 (4), e13142, 2020 | 157 | 2020 |
The factor inhibiting HIF asparaginyl hydroxylase regulates oxidative metabolism and accelerates metabolic adaptation to hypoxia J Sim, AS Cowburn, A Palazon, B Madhu, PA Tyrakis, D Macías, ... Cell metabolism 27 (4), 898-913. e7, 2018 | 71 | 2018 |
Oxygen-sensing by arterial chemoreceptors: mechanisms and medical translation J López-Barneo, P Ortega-Sáenz, P González-Rodríguez, ... Molecular Aspects of Medicine 47, 90-108, 2016 | 67 | 2016 |
HIF-2α is essential for carotid body development and function D Macias, AS Cowburn, H Torres-Torrelo, P Ortega-Saenz, ... Elife 7, e34681, 2018 | 61 | 2018 |
Deletion of the von Hippel–Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor‐mediated adaptation to hypoxia D Macías, MC Fernández‐Agüera, V Bonilla‐Henao, J López‐Barneo EMBO molecular medicine 6 (12), 1577-1592, 2014 | 57 | 2014 |
The role of Olfr78 in the breathing circuit of mice H Torres-Torrelo, P Ortega-Sáenz, D Macías, M Omura, T Zhou, ... Nature 561 (7724), E33-E40, 2018 | 56 | 2018 |
A sensor for low environmental oxygen in the mouse main olfactory epithelium K Bleymehl, A Pérez-Gómez, M Omura, A Moreno-Perez, D Macías, Z Bai, ... Neuron 92 (6), 1196-1203, 2016 | 53 | 2016 |
Cardiovascular adaptation to hypoxia and the role of peripheral resistance AS Cowburn, D Macias, C Summers, ER Chilvers, RS Johnson Elife 6, e28755, 2017 | 45 | 2017 |
Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells R Talaverón, ER Matarredona, RR de la Cruz, D Macías, V Gálvez, ... Glia 62 (4), 623-638, 2014 | 34 | 2014 |
Carotid body oxygen sensing and adaptation to hypoxia J López-Barneo, D Macías, A Platero-Luengo, P Ortega-Sáenz, R Pardal Pflügers Archiv-European Journal of Physiology 468, 59-70, 2016 | 31 | 2016 |
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer S Haston, E Gonzalez-Gualda, S Morsli, J Ge, V Reen, A Calderwood, ... Cancer Cell 41 (7), 1242-1260. e6, 2023 | 29 | 2023 |
Identification of a gene involved in the juvenile-to-adult transition (JAT) in cultivated olive trees A Fernández-Ocaña, M Carmen García-López, J Jiménez-Ruiz, L Saniger, ... Tree genetics & genomes 6, 891-903, 2010 | 26 | 2010 |
Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension D Macias, S Moore, A Crosby, M Southwood, X Du, H Tan, S Xie, ... European Respiratory Journal 57 (3), 2021 | 25 | 2021 |
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion P Ortega‐Sáenz, D Macías, KL Levitsky, JA Rodríguez‐Gómez, ... The Journal of Physiology 594 (24), 7229-7248, 2016 | 23 | 2016 |
Glycolytic response to inflammation over time: role of myeloid HIF-1alpha SF Fitzpatrick, M Gojkovic, D Macias, T Tegnebratt, L Lu, E Samén, ... Frontiers in physiology 9, 1624, 2018 | 14 | 2018 |
Gene therapy for HIV-1 infection: are lethal genes a valuable tool F Luque, R Oya, D Macias, L Saniger Cell Mol Biol 51, 93-101, 2005 | 12 | 2005 |