Muscle-specific Calpain, p94, Responsible for Limb Girdle Muscular Dystrophy Type 2A, Associates with Connectin through IS2, a p94-specific Sequence (∗) H Sorimachi, K Kinbara, S Kimura, M Takahashi, S Ishiura, N Sasagawa, ... Journal of Biological Chemistry 270 (52), 31158-31162, 1995 | 417 | 1995 |
Selective deficiency of α-dystroglycan in Fukuyama-type congenital muscular dystrophy YK Hayashi, M Ogawa, K Tagawa, S Noguchi, T Ishihara, I Nonaka, ... Neurology 57 (1), 115-121, 2001 | 256 | 2001 |
Mutant huntingtin impairs Ku70-mediated DNA repair Y Enokido, T Tamura, H Ito, A Arumughan, A Komuro, H Shiwaku, M Sone, ... Journal of Cell Biology 189 (3), 425-443, 2010 | 149 | 2010 |
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease K Fujita, K Motoki, K Tagawa, X Chen, H Hama, K Nakajima, H Homma, ... Scientific reports 6 (1), 31895, 2016 | 136 | 2016 |
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases ML Qi, K Tagawa, Y Enokido, N Yoshimura, Y Wada, K Watase, S Ishiura, ... Nature cell biology 9 (4), 402-414, 2007 | 121 | 2007 |
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73 M Hoshino, M Qi, N Yoshimura, T Miyashita, K Tagawa, Y Wada, ... The Journal of cell biology 172 (4), 589-604, 2006 | 99 | 2006 |
The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes K Tagawa, S Marubuchi, ML Qi, Y Enokido, T Tamura, R Inagaki, ... Journal of Neuroscience 27 (4), 868-880, 2007 | 94 | 2007 |
Dysferlin interacts with affixin (β-parvin) at the sarcolemma C Matsuda, K Kameyama, K Tagawa, M Ogawa, A Suzuki, S Yamaji, ... Journal of Neuropathology & Experimental Neurology 64 (4), 334-340, 2005 | 93 | 2005 |
Protein and gene analyses of dysferlinopathy in a large group of Japanese muscular dystrophy patients K Tagawa, M Ogawa, K Kawabe, G Yamanaka, T Matsumura, K Goto, ... Journal of the neurological sciences 211 (1-2), 23-28, 2003 | 93 | 2003 |
Alzheimer's disease amyloid β-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme K Tagawa, T Kunishita, K Maruyama, K Yoshikawa, E Kominami, ... Biochemical and biophysical research communications 177 (1), 377-387, 1991 | 88 | 1991 |
Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain K Tagawa, H Homma, A Saito, K Fujita, X Chen, S Imoto, T Oka, H Ito, ... Human molecular genetics 24 (2), 540-558, 2015 | 85 | 2015 |
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases K Fujita, Y Nakamura, T Oka, H Ito, T Tamura, K Tagawa, T Sasabe, ... Nature communications 4 (1), 1816, 2013 | 84 | 2013 |
Suppression of the novel ER protein Maxer by mutant ataxin‐1 in Bergman glia contributes to non‐cell‐autonomous toxicity H Shiwaku, N Yoshimura, T Tamura, M Sone, S Ogishima, K Watase, ... The EMBO journal 29 (14), 2446-2460, 2010 | 84 | 2010 |
HMGB 1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin‐1 knock‐in mice H Ito, K Fujita, K Tagawa, X Chen, H Homma, T Sasabe, J Shimizu, ... EMBO molecular medicine 7 (1), 78-101, 2015 | 83 | 2015 |
Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo T Okuda, K Tagawa, ML Qi, M Hoshio, H Ueda, H Kawano, I Kanazawa, ... Molecular brain research 132 (1), 18-30, 2004 | 80 | 2004 |
YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology H Tanaka, H Homma, K Fujita, K Kondo, S Yamada, X Jin, M Waragai, ... Nature communications 11 (1), 507, 2020 | 71 | 2020 |
Understanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain K Sato, A Kerever, K Kamagata, K Tsuruta, R Irie, K Tagawa, H Okazawa, ... Acta radiologica open 6 (4), 2058460117703816, 2017 | 70 | 2017 |
Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular … K Tagawa, C Taya, Y Hayashi, M Nakagawa, Y Ono, R Fukuda, ... Human Molecular Genetics 9 (9), 1393-1402, 2000 | 62 | 2000 |
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein M Hoshino, K Tagawa, T Okuda, M Murata, K Oyanagi, N Arai, T Mizutani, ... Journal of neurochemistry 87 (1), 257-267, 2003 | 61 | 2003 |
Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network Y Nakamura, K Tagawa, T Oka, T Sasabe, H Ito, H Shiwaku, AR La Spada, ... Human molecular genetics 21 (5), 1099-1110, 2012 | 60 | 2012 |