Andrew Holland
Andrew Holland
Assistant Professor, Johns Hopkins University School of Medicine
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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
AJ Holland, DW Cleveland
Nature reviews Molecular cell biology 10 (7), 478, 2009
Losing balance: the origin and impact of aneuploidy in cancer: ‘Exploring aneuploidy: the significance of chromosomal imbalance’review series
AJ Holland, DW Cleveland
EMBO reports 13 (6), 501-514, 2012
Cep152 interacts with Plk4 and is required for centriole duplication
EM Hatch, A Kulukian, AJ Holland, DW Cleveland, T Stearns
Journal of Cell Biology 191 (4), 721-729, 2010
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E
Y Kim, AJ Holland, W Lan, DW Cleveland
Cell 142 (3), 444-455, 2010
Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability
AJ Holland, W Lan, S Niessen, H Hoover, DW Cleveland
Journal of Cell Biology 188 (2), 191-198, 2010
A two-step mechanism for epigenetic specification of centromere identity and function
D Fachinetti, HD Folco, Y Nechemia-Arbely, LP Valente, K Nguyen, ...
Nature cell biology 15 (9), 1056-1066, 2013
Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells
AJ Holland, D Fachinetti, JS Han, DW Cleveland
Proceedings of the National Academy of Sciences 109 (49), E3350-E3357, 2012
Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements
AJ Holland, DW Cleveland
Nature medicine 18 (11), 1630-1638, 2012
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
AD Silk, LM Zasadil, AJ Holland, B Vitre, DW Cleveland, BA Weaver
Proceedings of the National Academy of Sciences 110 (44), E4134-E4141, 2013
The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation
SS Taylor, MIF Scott, AJ Holland
Chromosome Research 12 (6), 599-616, 2004
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells
R Gassmann, AJ Holland, D Varma, X Wan, F Çivril, DW Cleveland, ...
Genes & development 24 (9), 957-971, 2010
Requirements for NuMA in maintenance and establishment of mammalian spindle poles
AD Silk, AJ Holland, DW Cleveland
Journal of Cell Biology 184 (5), 677-690, 2009
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle
AJ Holland, D Fachinetti, Q Zhu, M Bauer, IM Verma, EA Nigg, ...
Genes & development 26 (24), 2684-2689, 2012
Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction
AJ Holland, SS Taylor
Journal of cell science 119 (16), 3325-3336, 2006
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20
JS Han, AJ Holland, D Fachinetti, A Kulukian, B Cetin, DW Cleveland
Molecular cell 51 (1), 92-104, 2013
Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F
MDJ Gurden, AJ Holland, W Van Zon, A Tighe, MA Vergnolle, DA Andres, ...
Journal of cell science 123 (3), 321-330, 2010
Protein phosphatase 2A and separase form a complex regulated by separase autocleavage
AJ Holland, F Böttger, O Stemmann, SS Taylor
Journal of Biological Chemistry 282 (34), 24623-24632, 2007
Disease-associated mutations cause premature oligomerization of myelin proteolipid protein in the endoplasmic reticulum
E Swanton, A Holland, S High, P Woodman
Proceedings of the National Academy of Sciences 102 (12), 4342-4347, 2005
Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis
AJ Holland, D Fachinetti, S Da Cruz, Q Zhu, B Vitre, M Lince-Faria, ...
Molecular biology of the cell 23 (10), 1838-1845, 2012
Polo-like kinase 4 inhibition: a strategy for cancer therapy?
AJ Holland, DW Cleveland
Cancer Cell 26 (2), 151-153, 2014
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Artículos 1–20