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Rafael Mayoral Monibas
Rafael Mayoral Monibas
Associate Director, Translational Science R&D at Corcept Therapeutics
Dirección de correo verificada de corcept.com - Página principal
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Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
A González-Rodríguez, R Mayoral, N Agra, MP Valdecantos, V Pardo, ...
Cell Death & Disease 5 (e1179), 1-13, 2014
5692014
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
B Chaurasia, TS Tippetts, R Mayoral Monibas, J Liu, Y Li, L Wang, ...
Science 365 (6451), 386-392, 2019
3512019
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
P Li, D Oh, G Bandyopadhyay, WS Lagakos, O Osborn, A Johnson, ...
Nature Medicine, 2015
3192015
GPR43 potentiates beta cell function in obesity.
JC McNelis, YS Lee, R Mayoral, R van der Kant, AM Johnson, J Wollam, ...
Diabetes, 2015
2082015
Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice
H Morinaga, R Mayoral, J Heinrichsdorff, O Osborn, N Franck, N Hah, ...
Diabetes 64 (4), 1120-1130, 2015
1862015
Adipocyte SIRT1 Knockout Promotes PPARγ Activity, Adipogenesis and Insulin Sensitivity in Chronic-HFD and Obesity
R Mayoral, O Osborn, J McNelis, AM Johnson, D Oh, C Lorente Izquierdo, ...
Molecular Metabolism, 2015
1582015
Prostaglandin E 2 promotes migration and adhesion in hepatocellular carcinoma cells
R Mayoral, A Fernández-Martínez, L Boscá, P Martín-Sanz
Carcinogenesis 26 (4), 753-761, 2005
1472005
Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C
C García-Monzón, OL Iacono, R Mayoral, Á González-Rodríguez, ...
Journal of hepatology 54 (1), 142-152, 2011
1152011
TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase
RP Matthews, K Lorent, R Mañoral-Mobias, Y Huang, W Gong, IVJ Murray, ...
Oxford University Press for The Company of Biologists Limited 136 (5), 865-875, 2009
982009
Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production Leading to Improved Insulin Sensitivity
ACSKM Wei Ying, Sumana Mahata, Gautam K. Bandyopadhyay, Zhenqi Zhou, Joshua ...
Diabetes, 2018
732018
Protection against Fas‐induced liver apoptosis in transgenic mice expressing cyclooxygenase 2 in hepatocytes
M Casado, B Mollá, R Roy, A Fernández‐Martínez, C Cucarella, ...
Hepatology 45 (3), 631-638, 2007
692007
Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer
H Chung, Y Lee, R Mayoral, D Oh, JT Siu, NJ Webster, DD Sears, ...
Oncogene, 1-10 doi:10.1038/onc.2014.283, 2014
662014
Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity and insulin resistance.
DE Francés, O Motiño, N Agrá, A González-Rodríguez, ...
Diabetes, 2014
622014
Dispensability and dynamics of caveolin‐1 during liver regeneration and in isolated hepatic cells
R Mayoral, A Fernández‐Martínez, R Roy, L Boscá, P Martín‐Sanz
Hepatology 46 (3), 813-822, 2007
592007
COX-2 in liver, from regeneration to hepatocarcinogenesis: what we have learned from animal models?
P Martín-Sanz, R Mayoral, M Casado, L Boscá
World journal of gastroenterology: WJG 16 (12), 1430, 2010
522010
Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice
O Motiño, N Agra, RB Contreras, M Domínguez-Moreno, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016
502016
Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17
J Moreno-Càceres, L Caja, J Mainez, R Mayoral, P Martín-Sanz, ...
Cell Death and Disease 5 (e1326), 2014
502014
Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells
N Agra Andrieu, O Motino, R Mayoral, C Llorente Izquierdo, ...
PLoS One 7 (11), e50935, 2012
472012
Protein tyrosine phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in mice
J Revuelta-Cervantes, R Mayoral, S Miranda, Á González-Rodríguez, ...
The American journal of pathology 178 (4), 1591-1604, 2011
472011
REGULATION OF miR-183 BY CYCLOOXYGENASE-2 IN LIVER IS DEAD BOX HELICASE p68 (DDX5) DEPENDENT. ROLE IN INSULIN SIGNALING.
MSP Motiño O, Francés DE, Mayoral R, Castro-Sánchez L, Fernández-Velasco M ...
Mol Cell Biol, 2015
46*2015
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Artículos 1–20