mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer G Cafri, JJ Gartner, T Zaks, K Hopson, N Levin, BC Paria, MR Parkhurst, ... The Journal of clinical investigation 130 (11), 5976-5988, 2020 | 269 | 2020 |
Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers MR Parkhurst, PF Robbins, E Tran, TD Prickett, JJ Gartner, L Jia, G Ivey, ... Cancer discovery 9 (8), 1022-1035, 2019 | 204 | 2019 |
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy R Yossef, E Tran, DC Deniger, A Gros, A Pasetto, MR Parkhurst, ... JCI insight 3 (19), 2018 | 202 | 2018 |
Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients G Cafri, R Yossef, A Pasetto, DC Deniger, YC Lu, M Parkhurst, JJ Gartner, ... Nature communications 10 (1), 449, 2019 | 133 | 2019 |
Antigen experienced T cells from peripheral blood recognize p53 neoantigens P Malekzadeh, R Yossef, G Cafri, BC Paria, FJ Lowery, M Jafferji, ... Clinical Cancer Research 26 (6), 1267-1276, 2020 | 91 | 2020 |
Membrane-anchored β2-microglobulin stabilizes a highly receptive state of MHC class I molecules D Berko, Y Carmi, G Cafri, S Ben-Zaken, HM Sheikhet, E Tzehoval, ... The Journal of Immunology 174 (4), 2116-2123, 2005 | 45 | 2005 |
Cryoimmunotherapy with local co-administration of ex vivo generated dendritic cells and CpG-ODN immune adjuvant, elicits a specific antitumor immunity Z Alteber, M Azulay, G Cafri, E Vadai, E Tzehoval, L Eisenbach Cancer Immunology, Immunotherapy 63, 369-380, 2014 | 40 | 2014 |
Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy N Levin, BC Paria, NR Vale, R Yossef, FJ Lowery, MR Parkhurst, Z Yu, ... Clinical Cancer Research 27 (18), 5084-5095, 2021 | 26 | 2021 |
mRNA-transfected dendritic cells expressing polypeptides that link MHC-I presentation to constitutive TLR4 activation confer tumor immunity G Cafri, A Sharbi-Yunger, E Tzehoval, Z Alteber, T Gross, E Vadai, ... Molecular Therapy 23 (8), 1391-1400, 2015 | 22 | 2015 |
Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models M Grees, A Sharbi-Yunger, C Evangelou, D Baumann, G Cafri, ... Oncoimmunology 7 (7), e1445457, 2018 | 21 | 2018 |
Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma V Leko, G Cafri, R Yossef, B Paria, V Hill, D Gurusamy, Z Zheng, ... Journal for Immunotherapy of Cancer 9 (7), 2021 | 20 | 2021 |
Production of LacZ Inducible T Cell Hybridoma Specific for Human and Mouse gp10025–33 Peptides G Cafri, A Sharbi-Yunger, E Tzehoval, L Eisenbach PloS one 8 (2), e55583, 2013 | 19 | 2013 |
Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers. Cancer Discov. 2019; 9: 1022–1035. doi: 10.1158/2159-8290 MR Parkhurst, PF Robbins, E Tran, TD Prickett, JJ Gartner, L Jia, G Ivey, ... CD-18-1494.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 19 | |
Messenger RNA encoding constitutively active toll-like receptor 4 enhances effector functions of human T cells A Pato, G Eisenberg, A Machlenkin, A Margalit, G Cafri, S Frankenburg, ... Clinical & Experimental Immunology 182 (2), 220-229, 2015 | 18 | 2015 |
Immunogenicity and tolerability of personalized mRNA vaccine mRNA-4650 encoding defined neoantigens expressed by the autologous cancer. G Cafri, JJ Gartner, K Hopson, RS Meehan, TZ Zaks, P Robbins, ... Journal of Clinical Oncology 37 (15_suppl), 2643-2643, 2019 | 16 | 2019 |
Spontaneous activation of antigen-presenting cells by genes encoding truncated homo-oligomerizing derivatives of CD40 N Levin, A Pato, G Cafri, G Eisenberg, T Peretz, A Margalit, M Lotem, ... Journal of Immunotherapy 40 (2), 39-50, 2017 | 15 | 2017 |
Coupling presentation of MHC class I peptides to constitutive activation of antigen-presenting cells through the product of a single gene G Cafri, E Amram, G Rinott, G Koifman, S Fishman, Y Keisari, E Tzehoval, ... International immunology 23 (7), 453-461, 2011 | 15 | 2011 |
A universal anti‐cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survival A Sharbi‐Yunger, M Grees, G Cafri, D Bassan, SB Eichmüller, E Tzehoval, ... International journal of cancer 144 (4), 909-921, 2019 | 10 | 2019 |
Development of novel genetic cancer vaccines based on membrane‐attached β2 microglobulin G Cafri, A Margalit, E Tzehoval, L Eisenbach, G Gross Annals of the New York Academy of Sciences 1283 (1), 87-90, 2013 | 7 | 2013 |
Uncovering the modified immunopeptidome reveals insights into principles of PTM-driven antigenicity A Kacen, A Javitt, MP Kramer, D Morgenstern, T Tsaban, A Solomon, ... Biorxiv, 2021.04. 10.438991, 2021 | 6 | 2021 |