Follow
Yinmeng Yang
Yinmeng Yang
Beam Therapeutics, NIH
Verified email at beamtx.com
Title
Cited by
Cited by
Year
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
A Terunuma, N Putluri, P Mishra, EA Mathé, TH Dorsey, M Yi, TA Wallace, ...
The Journal of clinical investigation 124 (1), 398-412, 2014
4142014
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ...
Nature communications 7 (1), 12320, 2016
4052016
TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
Y Yang, ME Kohler, CD Chien, CT Sauter, E Jacoby, C Yan, Y Hu, ...
Science translational medicine 9 (417), eaag1209, 2017
1822017
MicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer
RS Hudson, M Yi, D Esposito, SA Glynn, AM Starks, Y Yang, AJ Schetter, ...
Oncogene 32 (35), 4139-4147, 2013
1432013
Basal-like breast cancer cells induce phenotypic and genomic changes in macrophages
DA Stewart, Y Yang, L Makowski, MA Troester
Molecular Cancer Research 10 (6), 727-738, 2012
1192012
Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD
E Jacoby, Y Yang, H Qin, CD Chien, JN Kochenderfer, TJ Fry
Blood, The Journal of the American Society of Hematology 127 (10), 1361-1370, 2016
1142016
Challenges and opportunities of allogeneic donor-derived CAR T cells
Y Yang, E Jacoby, TJ Fry
Current opinion in hematology 22 (6), 509-515, 2015
1142015
Immunobiology of chimeric antigen receptor T cells and novel designs
Z Walsh, Y Yang, ME Kohler
Immunological Reviews 290 (1), 100-113, 2019
222019
CD4 CAR T cells mediate CD8-like cytotoxic anti-leukemic effects resulting in leukemic clearance and are less susceptible to attenuation by endogenous TCR activation than CD8 …
Y Yang, T Lin, E Jacoby, H Qin, EG Gardner, CD Chien, DW Lee III, TJ Fry
Blood 126 (23), 100, 2015
162015
Effect of chronic endogenous antigen stimulation on CAR T cell persistence and memory formation
Y Yang, ME Kohler, TJ Fry
Blood 130, 166, 2017
102017
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity. Nat Commun 2016; 7: 12320
E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ...
Curr Opin Hematol 26 (6), 427-433, 2019
72019
Lineage switch as a relapse mechanism of pre-B acute lymphoblastic leukemia following CD19 CAR
E Jacoby, SM Nguyen, KM Welp, H Qin, Y Yang, CD Chien, J Shern, ...
Blood 126 (23), 2524, 2015
52015
A direct comparison of the in vivo efficacy and in vitro signaling of chimeric antigen receptors and endogenous T cell receptors
ME Kohler, Y Yang, G Sepulveda, TJ Fry
Blood 130, 4451, 2017
42017
Modeling retreatment of acute lymphoblastic leukemia with anti-CD19 chimeric antigen receptor T cell therapy
Y Yang, ME Kohler, TJ Fry
Blood 128 (22), 2806, 2016
22016
Late ALL relapse following CD19 CAR immune-pressure demonstrates reversible pan-antigen loss
E Jacoby, Y Yang, CD Chien, W Haso, H Qin, TJ Fry
Cancer Research 75 (15_Supplement), 4705-4705, 2015
22015
CD19 CAR T Cells Maintain Efficacy in the Allogeneic Environment but Mediate Acute Graft-Versus-Host-Disease Only in the Presence CD19+ Acute Lymphoblastic Leukemia
E Jacoby, H Qin, Y Yang, CD Chien, TJ Fry
Blood, The Journal of the American Society of Hematology 124 (21), 1115-1115, 2014
22014
Il-6 is non-essential to murine CD19 CAR efficacy, but can mediate acute GVHD following allogeneic BMT with CAR T cell infusion
E Jacoby, H Qin, J Kochenderfer, Y Yang, C Chien, T Fry
Journal for ImmunoTherapy of Cancer 3, 1-1, 2015
2015
Presence of Endogenous TCR Antigen in Vivo Attenuates Efficacy of Anti-CD19 Targeted CAR T Cell Therapy
Y Yang, CD Chien, E Jacoby, H Qin, W Haso, TJ Fry
Blood 124 (21), 3721, 2014
2014
The system can't perform the operation now. Try again later.
Articles 1–18