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Christopher D. Aretz
Christopher D. Aretz
Postdoctoral Fellow, University of Colorado Medical Campus
Dirección de correo verificada de cuanschutz.edu
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Synthesis and SAR Studies of 1H-Pyrrolo[2,3-b]pyridine-2-carboxamides as Phosphodiesterase 4B (PDE4B) Inhibitors
AK Vadukoot, S Sharma, CD Aretz, S Kumar, N Gautam, Y Alnouti, ...
ACS Medicinal Chemistry Letters 11 (10), 1848-1854, 2020
152020
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics …
CD Aretz, AK Vadukoot, CR Hopkins
Journal of Medicinal Chemistry 62 (19), 8682-8694, 2019
72019
Cyclopentane Formation from Flexible Precursors Using Samarium (II) Reagents
CD Aretz, H Escobedo, BJ Cowen
European Journal of Organic Chemistry 2018 (16), 1880-1884, 2018
72018
Further SAR on the (Phenylsulfonyl)piperazine Scaffold as Inhibitors of the Aedes aegypti Kir1 (AeKir) Channel and Larvicides
CD Aretz, SV Kharade, K Chronister, R Rusconi Trigueros, ...
ChemMedChem 16 (2), 319-327, 2021
52021
Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 (AeKir1 …
CD Aretz, MJ Morwitzer, AG Sanford, AM Hogan, MV Portillo, SV Kharade, ...
ACS infectious diseases 5 (6), 917-931, 2019
52019
Mechanism of SmI2 Reduction of 5-Bromo-6-oxo-6-phenylhexyl Methanesulfonate Studied by Spin Trapping with 2-Methyl-2-nitrosopropane
CD Aretz, JE McPeak, GR Eaton, SS Eaton, BJ Cowen
The Journal of Organic Chemistry 83 (17), 10688-10692, 2018
52018
Synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of mrgX1
S Sharma, Q Peng, AK Vadukoot, CD Aretz, AA Jensen, AI Wallick, ...
ACS Medicinal Chemistry Letters 13 (5), 841-847, 2022
12022
Further synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of MrgX1
S Sharma, Q Peng, A Vadukoot, C Aretz, A Jensen, A Wallick, X Dong, ...
2021
Discovery, synthesis and biological characterization of a series of N-(1-(1, 1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1 H-pyrazol-5-yl) acetamide ethers as novel GIRK1/2 …
S Sharma, L Lesiak, CD Aretz, Y Du, S Kumar, N Gautam, Y Alnouti, ...
RSC Medicinal Chemistry 12 (8), 1366-1373, 2021
2021
Discovery and characterization of a novel class of phenylsulfonylpiperazine containing compounds as inhibitors of the Aedes aegypti Kir1 (AeKir1) potassium …
JB Mccarthey, CD Aretz, MD Morwitzer, AG Sanford, AM Hogan, ...
The FASEB Journal 33 (S1), 862.8-862.8, 2019
2019
Selective Carbon-Carbon Bond Formation Promoted by Divalent Samarium Reagents
CDJ Aretz
2018
Stereoselective samarium diiodide promoted carbon carbon bond forming reactions
C Aretz, H Escobedo, B Cowen
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
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