| The anaplastic lymphoma kinase in the pathogenesis of cancer R Chiarle, C Voena, C Ambrogio, R Piva, G Inghirami Nature Reviews Cancer 8 (1), 11-23, 2008 | 1022 | 2008 |
| Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death A Zamo, R Chiarle, R Piva, J Howes, Y Fan, M Chilosi, DE Levy, ... Oncogene 21 (7), 1038-1047, 2002 | 482 | 2002 |
| Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma R Crescenzo, F Abate, E Lasorsa, M Gaudiano, N Chiesa, F Di Giacomo, ... Cancer cell 27 (4), 516-532, 2015 | 440 | 2015 |
| CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib R Piva, B Ruggeri, M Williams, G Costa, I Tamagno, D Ferrero, V Giai, ... Blood, The Journal of the American Society of Hematology 111 (5), 2765-2775, 2008 | 327 | 2008 |
| NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors R Chiarle, JZ Gong, I Guasparri, A Pesci, J Cai, J Liu, WJ Simmons, ... Blood, The Journal of the American Society of Hematology 101 (5), 1919-1927, 2003 | 311 | 2003 |
| NF-κB: a stress-regulated switch for cell survival R Piva, G Belardo, MG Santoro Antioxidants & redox signaling 8 (3-4), 478-486, 2006 | 229 | 2006 |
| c-Jun, JNK/SAPK kinases and transcription factor NF-κB are selectively activated in astrocytes, but not motor neurons, in amyotrophic lateral sclerosis A Migheli, R Piva, C Atzori, D Troost, D Schiffer Journal of Neuropathology & Experimental Neurology 56 (12), 1314-1322, 1997 | 201 | 1997 |
| Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis C Atzori, B Ghetti, R Piva, AN Srinivasan, P Zolo, MB Delisle, SS Mirra, ... Journal of Neuropathology & Experimental Neurology 60 (12), 1190-1197, 2001 | 196 | 2001 |
| Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and Bcl2A1 as critical target genes R Piva, E Pellegrino, M Mattioli, L Agnelli, L Lombardi, F Boccalatte, ... The Journal of clinical investigation 116 (12), 3171-3182, 2006 | 190 | 2006 |
| Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ... J Clin Oncol 28 (9), 1583-1590, 2010 | 181 | 2010 |
| Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas R Piva, R Chiarle, AD Manazza, R Taulli, W Simmons, C Ambrogio, ... Blood 107 (2), 689-697, 2006 | 178 | 2006 |
| New and old functions of STAT3: a pivitol target for individualized treatment of cancer G Inghirami, R Chiarle, WJ Simmons, R Piva, K Schlessinger, DE Levy Cell cycle 4 (9), 1131-1133, 2005 | 173 | 2005 |
| Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition MR Sapienza, F Fuligni, C Agostinelli, C Tripodo, S Righi, MA Laginestra, ... Leukemia 28 (8), 1606-1616, 2014 | 171 | 2014 |
| Anaplastic lymphoma kinase in human cancer A Barreca, E Lasorsa, L Riera, R Machiorlatti, R Piva, M Ponzoni, I Kwee, ... Journal of molecular endocrinology 47 (1), R11-R23, 2011 | 165 | 2011 |
| S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase R Chiarle, Y Fan, R Piva, H Boggino, J Skolnik, D Novero, G Palestro, ... The American journal of pathology 160 (4), 1457-1466, 2002 | 143 | 2002 |
| PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas D Laimer, H Dolznig, K Kollmann, PW Vesely, M Schlederer, O Merkel, ... Nature medicine 18 (11), 1699-1704, 2012 | 141 | 2012 |
| Molecular profiling improves classification and prognostication of nodal peripheral T-cell lymphomas: results of a phase III diagnostic accuracy study PP Piccaluga, F Fuligni, A De Leo, C Bertuzzi, M Rossi, F Bacci, ... J Clin Oncol 31 (24), 3019-3025, 2013 | 140 | 2013 |
| 15-Deoxy-Δ12, 14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-κB activity and down-regulation of antiapoptotic proteins R Piva, P Gianferretti, A Ciucci, R Taulli, G Belardo, MG Santoro Blood 105 (4), 1750-1758, 2005 | 135 | 2005 |
| Activated p38MAPK is a novel component of the intracellular inclusions found in human amyotrophic lateral sclerosis and mutant SOD1 transgenic mice C Bendotti, C Atzori, R Piva, M Tortarolo, MJ Strong, S Debiasi, A Migheli Journal of Neuropathology & Experimental Neurology 63 (2), 113-119, 2004 | 131 | 2004 |
| PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma M Boi, A Rinaldi, I Kwee, P Bonetti, M Todaro, F Tabbo, R Piva, ... Blood, The Journal of the American Society of Hematology 122 (15), 2683-2693, 2013 | 130 | 2013 |
