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Yongyuth Yuthavong
Yongyuth Yuthavong
National Science and Technology Development Agency, Thailand
Dirección de correo verificada de biotec.or.th
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Insights into antifolate resistance from malarial DHFR-TS structures
J Yuvaniyama, P Chitnumsub, S Kamchonwongpaisan, J Vanichtanankul, ...
Nature Structural & Molecular Biology 10 (5), 357-365, 2003
4712003
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu)
SR Meshnick, YZ Yang, V Lima, F Kuypers, S Kamchonwongpaisan, ...
Antimicrobial agents and chemotherapy 37 (5), 1108-1114, 1993
4281993
Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase
W Sirawaraporn, T Sathitkul, R Sirawaraporn, Y Yuthavong, DV Santi
Proceedings of the National Academy of Sciences 94 (4), 1124-1129, 1997
4071997
A research agenda for malaria eradication: vector control
malERA Consultative Group on Vector Control
PLoS medicine 8 (1), e1000401, 2011
369*2011
Possible modes of action of the artemisinin-type compounds
PL Olliaro, RK Haynes, B Meunier, Y Yuthavong
Trends in parasitology 17 (3), 122-126, 2001
3152001
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Y Yuthavong, B Tarnchompoo, T Vilaivan, P Chitnumsub, ...
Proceedings of the National Academy of Sciences 109 (42), 16823-16828, 2012
2752012
Antimalarial sesquiterpenes from tubers of Cyperus rotundus: structure of 10, 12-peroxycalamenene, a sesquiterpene endoperoxide
C Thebtaranonth, Y Thebtaranonth, S Wanauppathamkul, Y Yuthavong
Phytochemistry 40 (1), 125-128, 1995
2671995
An overview of chemotherapeutic targets for antimalarial drug discovery
PL Olliaro, Y Yuthavong
Pharmacology & therapeutics 81 (2), 91-110, 1999
2561999
The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress
SR Krungkrai, Y Yuthavong
Transactions of the Royal Society of Tropical Medicine and Hygiene 81 (5 …, 1987
2561987
Inducible knockdown of Plasmodium gene expression using the glmS ribozyme
P Prommana, C Uthaipibull, C Wongsombat, S Kamchonwongpaisan, ...
PloS one 8 (8), e73783, 2013
2462013
Nimbolide, a constituent of Azadirachta indica, inhibits Plasmodium falciparum in culture.
S Rochanakij, Y Thebtaranonth, C Yenjai, Y Yuthavong
The Southeast Asian journal of tropical medicine and public health 16 (1), 66-72, 1985
2041985
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance
G Rastelli, W Sirawaraporn, P Sompornpisut, T Vilaivan, ...
Bioorganic & medicinal chemistry 8 (5), 1117-1128, 2000
1552000
Kinetic specificity in papain-catalysed hydrolyses
G Lowe, Y Yuthavong
Biochemical Journal 124 (1), 107-115, 1971
1451971
Inhibitors of Multiple Mutants of Plasmodium falciparum Dihydrofolate Reductase and Their Antimalarial Activities
S Kamchonwongpaisan, R Quarrell, N Charoensetakul, R Ponsinet, ...
Journal of medicinal chemistry 47 (3), 673-680, 2004
1382004
A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates
K Ganesan, N Ponmee, L Jiang, JW Fowble, J White, ...
PLoS pathogens 4 (11), e1000214, 2008
1342008
Basis for antifolate action and resistance in malaria
Y Yuthavong
Microbes and infection 4 (2), 175-182, 2002
1302002
Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX
S Paitayatat, B Tarnchompoo, Y Thebtaranonth, Y Yuthavong
Journal of medicinal chemistry 40 (5), 633-638, 1997
1291997
The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants.
W Sirawaraporn, P Prapunwattana, R Sirawaraporn, Y Yuthavong, ...
Journal of biological chemistry 268 (29), 21637-21644, 1993
1241993
Malarial (Plasmodium falciparum) dihydrofolate reductase-thymidylate synthase: structural basis for antifolate resistance and development of effective inhibitors
Y Yuthavong, J Yuvaniyama, P Chitnumsub, J Vanichtanankul, ...
Parasitology 130 (3), 249-259, 2005
1222005
Development of 2, 4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+ S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant …
B Tarnchompoo, C Sirichaiwat, W Phupong, C Intaraudom, ...
Journal of medicinal chemistry 45 (6), 1244-1252, 2002
1142002
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