| Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer S Signoretti, L Di Marcotullio, A Richardson, S Ramaswamy, B Isaac, ... The Journal of clinical investigation 110 (5), 633-641, 2002 | 413 | 2002 |
| Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells E Ferretti, E De Smaele, E Miele, P Laneve, A Po, M Pelloni, A Paganelli, ... The EMBO journal 27 (19), 2616-2627, 2008 | 398 | 2008 |
| Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation G Canettieri, L Di Marcotullio, A Greco, S Coni, L Antonucci, P Infante, ... Nature cell biology 12 (2), 132-142, 2010 | 375 | 2010 |
| Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination LD Marcotullio, E Ferretti, A Greco, E De Smaele, A Po, MA Sico, ... Nature cell biology 8 (12), 1415-1423, 2006 | 347 | 2006 |
| MicroRNA profiling in human medulloblastoma E Ferretti, E De Smaele, A Po, L Di Marcotullio, E Tosi, MSB Espinola, ... International journal of cancer 124 (3), 568-577, 2009 | 346 | 2009 |
| p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis G Rodier, A Montagnoli, L Di Marcotullio, P Coulombe, GF Draetta, ... The EMBO journal, 2001 | 346 | 2001 |
| Hedgehog controls neural stem cells through p53‐independent regulation of Nanog A Po, E Ferretti, E Miele, E De Smaele, A Paganelli, G Canettieri, S Coni, ... The EMBO journal 29 (15), 2646-2658, 2010 | 255 | 2010 |
| The multiple functions of Numb A Gulino, L Di Marcotullio, I Screpanti Experimental cell research 316 (6), 900-906, 2010 | 234 | 2010 |
| RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma L Di Marcotullio, E Ferretti, E De Smaele, B Argenti, C Mincione, ... Proceedings of the National Academy of Sciences 101 (29), 10833-10838, 2004 | 218 | 2004 |
| The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells P Laneve, L Di Marcotullio, U Gioia, ME Fiori, E Ferretti, A Gulino, ... Proceedings of the National Academy of Sciences 104 (19), 7957-7962, 2007 | 188 | 2007 |
| Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 183 | 2015 |
| Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal L Di Marcotullio, A Greco, D Mazzà, G Canettieri, L Pietrosanti, P Infante, ... Oncogene 30 (1), 65-76, 2011 | 136 | 2011 |
| Targeting GLI factors to inhibit the Hedgehog pathway P Infante, R Alfonsi, B Botta, M Mori, L Di Marcotullio Trends in pharmacological sciences 36 (8), 547-558, 2015 | 116 | 2015 |
| Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma A Po, M Silvano, E Miele, C Capalbo, A Eramo, V Salvati, M Todaro, ... Oncogene 36 (32), 4641-4652, 2017 | 100 | 2017 |
| Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma E De Smaele, L Di Marcotullio, M Moretti, M Pelloni, MA Occhione, ... Neoplasia 13 (4), 374-IN23, 2011 | 98 | 2011 |
| PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress D Mazza, P Infante, V Colicchia, A Greco, R Alfonsi, M Siler, L Antonucci, ... Cell Death & Differentiation 20 (12), 1688-1697, 2013 | 95 | 2013 |
| Hedgehog antagonist RENKCTD11 regulates proliferation and apoptosis of developing granule cell progenitors B Argenti, R Gallo, L Di Marcotullio, E Ferretti, M Napolitano, S Canterini, ... Journal of Neuroscience 25 (36), 8338-8346, 2005 | 93 | 2005 |
| Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm E Ferretti, E De Smaele, L Di Marcotullio, I Screpanti, A Gulino Trends in molecular medicine 11 (12), 537-545, 2005 | 92 | 2005 |
| EGF‐ and cell‐cycle–regulated STAG1/PMEPA1/ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer G Giannini, MI Ambrosini, L Di Marcotullio, F Cerignoli, M Zani, ... Molecular Carcinogenesis: Published in cooperation with the University of …, 2003 | 90 | 2003 |
| New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer G La Regina, R Bai, A Coluccia, V Famiglini, S Pelliccia, S Passacantilli, ... Journal of medicinal chemistry 57 (15), 6531-6552, 2014 | 84 | 2014 |
