A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors E Doumazane, P Scholler, JM Zwier, E Trinquet, P Rondard, JP Pin The FASEB Journal 25 (1), 66-77, 2011 | 332 | 2011 |
Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling D El Moustaine, S Granier, E Doumazane, P Scholler, R Rahmeh, P Bron, ... Proceedings of the National Academy of Sciences 109 (40), 16342-16347, 2012 | 211 | 2012 |
Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors E Doumazane, P Scholler, L Fabre, JM Zwier, E Trinquet, JP Pin, ... Proceedings of the National Academy of Sciences 110 (15), E1416-E1425, 2013 | 124 | 2013 |
Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy L Olofsson, S Felekyan, E Doumazane, P Scholler, L Fabre, JM Zwier, ... Nature communications 5 (1), 5206, 2014 | 105 | 2014 |
BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues M Cottet, O Faklaris, D Maurel, P Scholler, E Doumazane, E Trinquet, ... Frontiers in endocrinology 3, 92, 2012 | 84 | 2012 |
HTS-compatible FRET-based conformational sensors clarify membrane receptor activation P Scholler, D Moreno-Delgado, N Lecat-Guillet, E Doumazane, ... Nature chemical biology 13 (4), 372-380, 2017 | 52 | 2017 |
Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling C Duquenne, S Gimenez, A Guigues, B Viala, C Boulouis, C Mettling, ... AIDS 31 (18), 2443-2454, 2017 | 8 | 2017 |
Time-resolved FRET approaches to study GPCR complexes JP Pin, D Maurel, L Comps-Agrar, C Monnier, ML Rives, E Doumazane, ... G Protein-Coupled Receptors: Structure, Signaling, and Physiology, 67-89, 2010 | 4 | 2010 |
Method for detecting compounds modulating dimers of VFT domain membrane proteins E Doumazane, J Zwier, E Trinquet, JP Pin US Patent 8,697,380, 2014 | 2 | 2014 |
Specific Regulation of Transition Rates between Active and Inactive States of the Metabotropic Glutamate Receptor Determines Agonist Efficacy L Olofsson, E Doumazane, P Scholler, L Fabre, J Zwier, JP Pin, C Seidel, ... Biophysical Journal 106 (2), 100a-101a, 2014 | | 2014 |
Towards Functional and Pharmacological Characterization of mGlu Heterodimers D Moreno, P Scholler, E Doumazane, P Rondard, JP Pin CURRENT NEUROPHARMACOLOGY 12, 44-44, 2014 | | 2014 |
The metabotropic glutamate receptors: complex machines for new drugs JP Pin, D El-Moustaine, S Granier, E Doumazane, P Scholler, JL Baneres, ... JOURNAL OF NEUROCHEMISTRY 125, 46-46, 2013 | | 2013 |
A new Approach to Analyze Cell Surface mGluRs Reveals Allosteric Switches During Activation and Possible Heterodimers P Scholler, E Doumazane, L Fabre, G Donsimoni, JM Zwier, E Trinquet, ... CURRENT NEUROPHARMACOLOGY 9, 58-58, 2011 | | 2011 |
Structural Insights into Metabotropic Glutamate Receptors Activation D El-Moustaine, S Huang, E Doumazane, P Scholler, JL Baneres, ... CURRENT NEUROPHARMACOLOGY 9, 17-17, 2011 | | 2011 |
Structural Dynamics of Metabotropic Glutamate Receptors JP Pin, E Doumazane, P Scholler, D El-Moustaine, S Granier, B Mouillac, ... CURRENT NEUROPHARMACOLOGY 9, 53-53, 2011 | | 2011 |
mGluRs FRET sensors as new tools for high-throughput drug screening E Doumazane, P Scholler, L Fabre, G Donsimoni, A Jean, P Rondard, ... CURRENT NEUROPHARMACOLOGY 9, 16-16, 2011 | | 2011 |
mGlu receptors: complex allosteric machines to tune up synaptic transmission P Rondard, E Doumazane, P Scholler, E Trinquet, S Granier, JP Pin Program and Abstracts of the 2~(nd) International and 11~(th) National …, 2010 | | 2010 |
The allosteric conformation change of Cysteine-Rich Domains in activation process of Metabotropic Glutamate-like Receptor G Labesse, C Monnier, E Doumazane, JP Pin, P Rondard Abstracts of the First International Symposium on Membrane Biology--The …, 2009 | | 2009 |
upon complexation to G-proteins: a putative activation mode of GPCRs? P Scholler, E Doumazane, L Fabre, G Donsimoni, F Charrier-Savournin, ... | | |