David Hafler
David Hafler
Professor of Neurology and Immunobiology, Yale University
Dirección de correo verificada de yale.edu - Página principal
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Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
33442015
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
Y Chen, VK Kuchroo, J Inobe, DA Hafler, HL Weiner
Science 265 (5176), 1237-1240, 1994
23501994
CD4+ CD25high regulatory cells in human peripheral blood
C Baecher-Allan, JA Brown, GJ Freeman, DA Hafler
The Journal of Immunology 167 (3), 1245-1253, 2001
23212001
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
S Sawcer, G Hellenthal, M Pirinen, CCA Spencer, NA Patsopoulos, ...
Nature 476 (7359), 214, 2011
22072011
FOXP3+ regulatory T cells in the human immune system
S Sakaguchi, M Miyara, CM Costantino, DA Hafler
Nature Reviews Immunology 10 (7), 490-500, 2010
20942010
Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis
V Viglietta, C Baecher-Allan, HL Weiner, DA Hafler
The Journal of experimental medicine 199 (7), 971-979, 2004
19762004
Risk alleles for multiple sclerosis identified by a genomewide study
International Multiple Sclerosis Genetics Consortium
New England Journal of Medicine 357 (9), 851-862, 2007
17822007
Risk alleles for multiple sclerosis identified by a genomewide study
D Hafler
New England Journal of Medicine 357, 851, 2007
17822007
Genetic and epigenetic fine mapping of causal autoimmune disease variants
KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ...
Nature 518 (7539), 337-343, 2015
11622015
IL-21 and TGF-β are required for differentiation of human TH 17 cells
L Yang, DE Anderson, C Baecher-Allan, WD Hastings, E Bettelli, M Oukka, ...
Nature 454 (7202), 350-352, 2008
11222008
Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens
HL Weiner, A Friedman, A Miller, SJ Khoury, A Al-Sabbagh, L Santos, ...
Annual review of immunology 12 (1), 809-837, 1994
10621994
T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis
K Ota, M Matsui, EL Milford, GA Mackin, HL Weiner, DA Hafler
Nature 346 (6280), 183-187, 1990
9891990
Sodium chloride drives autoimmune disease by the induction of pathogenic TH 17 cells
M Kleinewietfeld, A Manzel, J Titze, H Kvakan, N Yosef, RA Linker, ...
Nature 496 (7446), 518-522, 2013
9152013
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
AH Beecham, NA Patsopoulos, DK Xifara, MF Davis, A Kemppinen, ...
Nature genetics 45 (11), 1353-1360, 2013
8422013
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
PL De Jager, X Jia, J Wang, PIW De Bakker, L Ottoboni, NT Aggarwal, ...
Nature genetics 41 (7), 776, 2009
8102009
Induction and molecular signature of pathogenic TH 17 cells
Y Lee, A Awasthi, N Yosef, FJ Quintana, S Xiao, A Peters, C Wu, ...
Nature immunology 13 (10), 991-999, 2012
7832012
Erratum: Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
SB Wilson, SC Kent, KT Patton, T Orban, RA Jackson, M Exley, S Porcelli, ...
Nature 399 (6731), 84-84, 1999
7831999
Effects of oral administration of type II collagen on rheumatoid arthritis
DE Trentham, RA Dynesius-Trentham, EJ Orav, D Combitchi, C Lorenzo, ...
Science 261 (5129), 1727-1730, 1993
7801993
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
PIW De Bakker, G McVean, PC Sabeti, MM Miretti, T Green, J Marchini, ...
Nature genetics 38 (10), 1166-1172, 2006
7772006
Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis
HL Weiner, GA Mackin, M Matsui, EJ Orav, SJ Khoury, DM Dawson, ...
Science 259 (5099), 1321-1324, 1993
7081993
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Artículos 1–20