| PLCζ: a sperm-specific trigger of Ca2+ oscillations in eggs and embryo development CM Saunders, MG Larman, J Parrington, LJ Cox, J Royse, LM Blayney, ... Oxford University Press for The Company of Biologists Limited 129 (15), 3533 …, 2002 | 1253 | 2002 |
| NAADP mobilizes calcium from acidic organelles through two-pore channels PJ Calcraft, M Ruas, Z Pan, X Cheng, A Arredouani, X Hao, J Tang, ... Nature 459 (7246), 596-600, 2009 | 866 | 2009 |
| Calcium oscillations in mammalian eggs triggered by a soluble sperm protein J Parrington, K Swann, VI Shevchenko, AK Sesay, FA Lai Nature 379 (6563), 364-368, 1996 | 472 | 1996 |
| Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development SY Yoon, T Jellerette, AM Salicioni, HC Lee, M Yoo, K Coward, ... The Journal of clinical investigation 118 (11), 3671-3681, 2008 | 368 | 2008 |
| Reduced amounts and abnormal forms of phospholipase C zeta (PLCζ) in spermatozoa from infertile men E Heytens, J Parrington, K Coward, C Young, S Lambrecht, SY Yoon, ... Human Reproduction 24 (10), 2417-2428, 2009 | 350 | 2009 |
| Oocyte activation, phospholipase C zeta and human infertility J Kashir, B Heindryckx, C Jones, P De Sutter, J Parrington, K Coward Human reproduction update 16 (6), 690-703, 2010 | 311 | 2010 |
| Purified TPC isoforms form NAADP receptors with distinct roles for Ca2+ signaling and endolysosomal trafficking M Ruas, K Rietdorf, A Arredouani, LC Davis, E Lloyd-Evans, H Koegel, ... Current biology 20 (8), 703-709, 2010 | 284 | 2010 |
| Gamete physiology, fertilization and egg activation in teleost fish K Coward, NR Bromage, O Hibbitt, J Parrington Reviews in Fish Biology and Fisheries 12, 33-58, 2002 | 265 | 2002 |
| TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ SJ Pitt, TM Funnell, M Sitsapesan, E Venturi, K Rietdorf, M Ruas, ... Journal of Biological Chemistry 285 (45), 35039-35046, 2010 | 247 | 2010 |
| VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2–dependent Ca2+ signaling A Favia, M Desideri, G Gambara, A D’Alessio, M Ruas, B Esposito, ... Proceedings of the National Academy of Sciences 111 (44), E4706-E4715, 2014 | 186 | 2014 |
| Expression of Ca2+‐permeable two‐pore channels rescues NAADP signalling in TPC‐deficient cells M Ruas, LC Davis, CC Chen, AJ Morgan, KT Chuang, TF Walseth, ... The EMBO journal 34 (13), 1743-1758, 2015 | 183 | 2015 |
| Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles AJ Morgan, LC Davis, SKTY Wagner, AM Lewis, J Parrington, ... Journal of Cell Biology 200 (6), 789-805, 2013 | 171 | 2013 |
| The pattern of localization of the putative oocyte activation factor, phospholipase Cζ, in uncapacitated, capacitated, and ionophore-treated human spermatozoa P Grasa, K Coward, C Young, J Parrington Human Reproduction 23 (11), 2513-2522, 2008 | 171 | 2008 |
| Calcium signaling via two-pore channels: local or global, that is the question MX Zhu, J Ma, J Parrington, PJ Calcraft, A Galione, AM Evans American Journal of Physiology-Cell Physiology 298 (3), C430-C441, 2010 | 166 | 2010 |
| A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility J Kashir, M Konstantinidis, C Jones, B Lemmon, H Chang Lee, R Hamer, ... Human reproduction 27 (1), 222-231, 2012 | 163 | 2012 |
| NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing LC Davis, AJ Morgan, JL Chen, CM Snead, D Bloor-Young, E Shenderov, ... Current Biology 22 (24), 2331-2337, 2012 | 150 | 2012 |
| Mammalian sperm contain a Ca2+-sensitive phospholipase C activity that can generate InsP3 from PIP2 associated with intracellular organelles A Rice, J Parrington, KT Jones, K Swann Developmental biology 228 (1), 125-135, 2000 | 144 | 2000 |
| PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence A Hachem, J Godwin, M Ruas, HC Lee, M Ferrer Buitrago, G Ardestani, ... Development 144 (16), 2914-2924, 2017 | 142 | 2017 |
| Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg*♦ TF Walseth, Y Lin-Moshier, P Jain, M Ruas, J Parrington, A Galione, ... Journal of Biological Chemistry 287 (4), 2308-2315, 2012 | 141 | 2012 |
| Ca2+‐stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea‐pig sino‐atrial node cells and modulates the If pacemaker current P Mattick, J Parrington, E Odia, A Simpson, T Collins, D Terrar The Journal of physiology 582 (3), 1195-1203, 2007 | 141 | 2007 |
