Alejandro Buschiazzo
TitleCited byYear
The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
A Buschiazzo, MF Amaya, ML Cremona, AC Frasch, PM Alzari
Molecular cell 10 (4), 757-768, 2002
2402002
Trypanosoma c ruzi Trans-sialidase Operates through a Covalent Sialyl-Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile
AG Watts, I Damager, ML Amaya, A Buschiazzo, P Alzari, AC Frasch, ...
Journal of the American Chemical Society 125 (25), 7532-7533, 2003
2262003
Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase
MF Amaya, AG Watts, I Damager, A Wehenkel, T Nguyen, A Buschiazzo, ...
Structure 12 (5), 775-784, 2004
2202004
Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation
A Buschiazzo, JE Ugalde, ME Guerin, W Shepard, RA Ugalde, PM Alzari
The EMBO journal 23 (16), 3196-3205, 2004
1622004
Structural plasticity and catalysis regulation of a thermosensor histidine kinase
D Albanesi, M Martín, F Trajtenberg, MC Mansilla, A Haouz, PM Alzari, ...
Proceedings of the National Academy of Sciences 106 (38), 16185-16190, 2009
1572009
Structural basis of sialyltransferase activity in trypanosomal sialidases
A Buschiazzo, GA Tavares, O Campetella, S Spinelli, ML Cremona, ...
The EMBO journal 19 (1), 16-24, 2000
1462000
Active nuclear import and cytoplasmic retention of activation-induced deaminase
AM Patenaude, A Orthwein, Y Hu, VA Campo, B Kavli, A Buschiazzo, ...
Nature structural & molecular biology 16 (5), 517-527, 2009
1372009
Identification of the gene (s) coding for the trans‐sialidase of Trypanosoma cruzi.
AJ Parodi, GD Pollevick, M Mautner, A Buschiazzo, DO Sanchez, ...
The EMBO journal 11 (5), 1705-1710, 1992
1301992
What Makes a Bacterial Species Pathogenic?: Comparative Genomic Analysis of the Genus Leptospira
DE Fouts, MA Matthias, H Adhikarla, B Adler, L Amorim-Santos, DE Berg, ...
PLOS Negl Trop Dis 10 (2), e0004403, 2016
1242016
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria
ME Guerin, J Kordulakova, F Schaeffer, Z Svetlikova, A Buschiazzo, ...
Journal of Biological Chemistry 282 (28), 20705-20714, 2007
1132007
Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase
AG Watts, P Oppezzo, SG Withers, PM Alzari, A Buschiazzo
Journal of Biological Chemistry 281 (7), 4149-4155, 2006
992006
A New Generation of Specific Trypanosoma cruzi trans‐Sialidase Inhibitors
S Buchini, A Buschiazzo, SG Withers
Angewandte Chemie International Edition 47 (14), 2700-2703, 2008
962008
Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase
A Buschiazzo, M Goytia, F Schaeffer, W Degrave, W Shepard, C Grégoire, ...
Proceedings of the National Academy of Sciences of the United States of …, 2006
962006
Structural basis of lipid biosynthesis regulation in Gram‐positive bacteria
GE Schujman, M Guerin, A Buschiazzo, F Schaeffer, LI Llarrull, G Reh, ...
The EMBO journal 25 (17), 4074-4083, 2006
942006
Structural insights into sialic acid enzymology
A Buschiazzo, PM Alzari
Current opinion in chemical biology 12 (5), 565-572, 2008
842008
The High Resolution Structures of Free and Inhibitor-bound Trypanosoma rangeli Sialidase and its Comparison with T. cruziTrans-sialidase
MF Amaya, A Buschiazzo, T Nguyen, PM Alzari
Journal of molecular biology 325 (4), 773-784, 2003
782003
Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes
G Moratorio, G Obal, A Dubra, A Correa, S Bianchi, A Buschiazzo, ...
Archives of virology 155 (4), 481-489, 2010
752010
Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis†
I Damager, S Buchini, MF Amaya, A Buschiazzo, P Alzari, AC Frasch, ...
Biochemistry 47 (11), 3507-3512, 2008
712008
The trans‐sialidase from the african trypanosome Trypanosoma brucei
G Montagna, ML Cremona, G Paris, MF Amaya, A Buschiazzo, PM Alzari, ...
The FEBS Journal 269 (12), 2941-2950, 2002
642002
Discovery of novel inhibitors of Trypanosoma cruzitrans-sialidase from in silico screening
J Neres, ML Brewer, L Ratier, H Botti, A Buschiazzo, PN Edwards, ...
Bioorganic & medicinal chemistry letters 19 (3), 589-596, 2009
612009
The system can't perform the operation now. Try again later.
Articles 1–20