| GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling CA Johnston, JP Taylor, Y Gao, AJ Kimple, JC Grigston, JG Chen, ... Proceedings of the National Academy of Sciences 104 (44), 17317-17322, 2007 | 246 | 2007 |
| Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells CA Johnston, K Hirono, KE Prehoda, CQ Doe Cell 138 (6), 1150-1163, 2009 | 239 | 2009 |
| RIC-8 is required for GPR-1/2-dependent Gα function during asymmetric division of C. elegans embryos K Afshar, FS Willard, K Colombo, CA Johnston, CR McCudden, ... Cell 119 (2), 219-230, 2004 | 221 | 2004 |
| Receptor-mediated activation of heterotrimeric G-proteins: current structural insights CA Johnston, DP Siderovski Molecular pharmacology 72 (2), 219-230, 2007 | 204 | 2007 |
| Molecular pathways regulating mitotic spindle orientation in animal cells MS Lu, CA Johnston Development 140 (9), 1843-1856, 2013 | 203 | 2013 |
| The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish M Ségalen, CA Johnston, CA Martin, JG Dumortier, KE Prehoda, ... Developmental cell 19 (5), 740-752, 2010 | 157 | 2010 |
| Comment on" AG Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid" CA Johnston, BR Temple, JG Chen, Y Gao, EN Moriyama, AM Jones, ... Science 318 (5852), 914-914, 2007 | 137 | 2007 |
| Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization MM Paing, CA Johnston, DP Siderovski, JA Trejo Molecular and cellular biology 26 (8), 3231-3242, 2006 | 132 | 2006 |
| Structure of Gαi1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange CA Johnston, FS Willard, MR Jezyk, Z Fredericks, ET Bodor, MB Jones, ... Structure 13 (7), 1069-1080, 2005 | 105 | 2005 |
| Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity NA Lambert, CA Johnston, SD Cappell, S Kuravi, AJ Kimple, FS Willard, ... Proceedings of the National Academy of Sciences 107 (15), 7066-7071, 2010 | 102 | 2010 |
| Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner A Sepahi, A Kraus, E Casadei, CA Johnston, J Galindo-Villegas, C Kelly, ... Proceedings of the National Academy of Sciences 116 (25), 12428-12436, 2019 | 82 | 2019 |
| Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation B Wee, CA Johnston, KE Prehoda, CQ Doe Journal of Cell Biology 195 (3), 369-376, 2011 | 74 | 2011 |
| The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face AJ Kimple, FS Willard, PM Giguère, CA Johnston, V Mocanu, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774 (9), 1213-1220, 2007 | 61 | 2007 |
| Structural basis for nucleotide exchange on Gαi subunits and receptor coupling specificity CA Johnston, DP Siderovski Proceedings of the National Academy of Sciences 104 (6), 2001-2006, 2007 | 58 | 2007 |
| A direct fluorescence-based assay for RGS domain GTPase accelerating activity FS Willard, AJ Kimple, CA Johnston, DP Siderovski Analytical biochemistry 340 (2), 341-351, 2005 | 56 | 2005 |
| A point mutation to Gαi selectively blocks GoLoco motif binding: Direct evidence for Gα· GoLoco complexes in mitotic spindle dynamics FS Willard, Z Zheng, J Guo, GJ Digby, AJ Kimple, JM Conley, ... Journal of biological chemistry 283 (52), 36698-36710, 2008 | 53 | 2008 |
| Multiple tail domain interactions stabilize nonmuscle myosin II bipolar filaments D Ricketson, CA Johnston, KE Prehoda Proceedings of the National Academy of Sciences 107 (49), 20964-20969, 2010 | 52 | 2010 |
| Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN CR McCudden, FS Willard, RJ Kimple, CA Johnston, MD Hains, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1745 (2), 254-264, 2005 | 52 | 2005 |
| Minimal Determinants for Binding Activated Gα from the Structure of a Gαi1−Peptide Dimer, CA Johnston, ES Lobanova, AS Shavkunov, J Low, JK Ramer, R Blaesius, ... Biochemistry 45 (38), 11390-11400, 2006 | 51 | 2006 |
| Sensitization of adenylate cyclase: a general mechanism of neuroadaptation to persistent activation of Gαi/o-coupled receptors? CA Johnston, VJ Watts Life sciences 73 (23), 2913-2925, 2003 | 47 | 2003 |
