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Andrew Harkin
Andrew Harkin
Professor in Pharmacology, Trinity College Dublin
Dirección de correo verificada de tcd.ie - Página principal
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The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
W Beumer, SM Gibney, RC Drexhage, L Pont-Lezica, J Doorduin, ...
Journal of leukocyte biology 92 (5), 959-975, 2012
4032012
Nitric oxide synthase inhibitors have antidepressant-like properties in mice: 1. Acute treatments are active in the forced swim test
AJ Harkin, KH Bruce, B Craft, IA Paul
European journal of pharmacology 372 (3), 207-213, 1999
2801999
Induction of indolamine 2, 3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-γ?
TJ Connor, N Starr, JB O'Sullivan, A Harkin
Neuroscience letters 441 (1), 29-34, 2008
2322008
Poly I: C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression
SM Gibney, B McGuinness, C Prendergast, A Harkin, TJ Connor
Brain, behavior, and immunity 28, 170-181, 2013
2232013
Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test
A Harkin, TJ Connor, MP Burns, JP Kelly
European Neuropsychopharmacology 14 (4), 274-281, 2004
1992004
Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism
V Gigliucci, G O’Dowd, S Casey, D Egan, S Gibney, A Harkin
Psychopharmacology 228, 157-166, 2013
1892013
Gut–brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease
Á Abautret-Daly, E Dempsey, A Parra-Blanco, C Medina, A Harkin
Acta neuropsychiatrica 30 (5), 275-296, 2018
1722018
Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors
A Harkin, TJ Connor, M Walsh, N St John, JP Kelly
Neuropharmacology 44 (5), 616-623, 2003
1602003
Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration
JB O'Sullivan, KM Ryan, NM Curtin, A Harkin, TJ Connor
International Journal of Neuropsychopharmacology 12 (5), 687-699, 2009
1482009
Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test
TJ Connor, P Kelliher, Y Shen, A Harkin, JP Kelly, BE Leonard
Pharmacology Biochemistry and Behavior 65 (4), 591-597, 2000
1392000
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression
A Harkin, JP Kelly, M McNamara, TJ Connor, K Dredge, A Redmond, ...
European journal of pharmacology 364 (2-3), 123-132, 1999
1381999
Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders
K O'Farrell, A Harkin
Neuropharmacology 112, 307-323, 2017
1372017
L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke
MI Cuartero, I Ballesteros, J de la Parra, AL Harkin, A Abautret-Daly, ...
Circulation 130 (23), 2040-2051, 2014
1272014
A review of the relevance and validity of olfactory bulbectomy as a model of depression
A Harkin, JP Kelly, BE Leonard
Clinical Neuroscience Research 3 (4-5), 253-262, 2003
1272003
Acute stress suppresses pro-inflammatory cytokines TNF-α and IL-1β independent of a catecholamine-driven increase in IL-10 production
TJ Connor, C Brewer, JP Kelly, A Harkin
Journal of neuroimmunology 159 (1-2), 119-128, 2005
1262005
Olfactory bulbectomy in mice induces alterations in exploratory behavior
M Zueger, A Urani, S Chourbaji, C Zacher, M Roche, A Harkin, P Gass
Neuroscience letters 374 (2), 142-146, 2005
1162005
Varying responses to the rat forced-swim test under diurnal and nocturnal conditions
P Kelliher, TJ Connor, A Harkin, C Sanchez, JP Kelly, BE Leonard
Physiology & behavior 69 (4-5), 531-539, 2000
1162000
Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation
MM Hughes, A Carballedo, DM McLoughlin, F Amico, A Harkin, T Frodl, ...
Brain, behavior, and immunity 26 (6), 979-987, 2012
1152012
DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic–pituitary–adrenal axis activity and to early …
C Farrell, K Doolin, N O’Leary, C Jairaj, D Roddy, L Tozzi, D Morris, ...
Psychiatry Research 265, 341-348, 2018
1072018
C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy
MM Pertl, D Hevey, NT Boyle, MM Hughes, S Collier, AM O’Dwyer, ...
Brain, behavior, and immunity 34, 108-119, 2013
1062013
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