Siddharth S. Kesharwani, MS (NIPER-Mohali), Ph.D.
Siddharth S. Kesharwani, MS (NIPER-Mohali), Ph.D.
Assistant Professor of Pharmaceutical Sciences
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Hydrophobically modified inulin as an amphiphilic carbohydrate polymer for micellar delivery of paclitaxel for intravenous route
P Muley, S Kumar, F El Kourati, SS Kesharwani, H Tummala
International journal of pharmaceutics 500 (1-2), 32-41, 2016
Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin
S Kumar, SS Kesharwani, H Mathur, M Tyagi, GJ Bhat, H Tummala
European Journal of Pharmaceutical Sciences 82, 86-96, 2016
Multifunctional approaches utilizing polymeric micelles to circumvent multidrug resistant tumors
SS Kesharwani, S Kaur, H Tummala, AT Sangamwar
Colloids and Surfaces B: Biointerfaces 173, 581-590, 2019
Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer
Rakesh Dachineni , D. Ramesh Kumar Eduardo Callegari, Siddharth S ...
International Journal of Oncology, 2017
Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): formulation development, characterization and pharmacological evaluation
SS Kesharwani, R Ahmad, MA Bakkari, MKS Rajput, R Dachineni, ...
Journal of Controlled Release 290, 165-179, 2018
The flavonoid metabolite 2, 4, 6-trihydroxybenzoic acid is a CDK inhibitor and an anti-proliferative agent: A potential role in cancer prevention
R Sankaranarayanan, CK Valiveti, DR Kumar, SS Kesharwani, T Seefeldt, ...
Cancers 11 (3), 427, 2019
Pathogen-mimicking vaccine delivery system designed with a bioactive polymer (inulin acetate) for robust humoral and cellular immune responses
Hemachand Tummala, Sunny Kumar, Siddharth S. Kesharwani, Bhimanna Kuppast ...
Journal of Controlled Release, 2017
Discovery of inulin acetate as a novel immune-active polymer and vaccine adjuvant: synthesis, material characterization, and biological evaluation as a toll-like receptor-4 agonist
S Kumar, SS Kesharwani, B Kuppast, M Rajput, MA Bakkari, H Tummala
Journal of Materials Chemistry B 4 (48), 7950-7960, 2016
Overcoming multiple drug resistance in cancer using polymeric micelles
SS Kesharwani, S Kaur, H Tummala, AT Sangamwar
Expert opinion on drug delivery 15 (11), 1127-1142, 2018
Dendritic cell-targeted nanovaccine delivery system prepared with an immune-active polymer
MKS Rajput, SS Kesharwani, S Kumar, P Muley, S Narisetty, H Tummala
ACS applied materials & interfaces 10 (33), 27589-27602, 2018
Predicting drug metabolism by CYP1A1, CYP1A2, and CYP1B1: insights from MetaSite, molecular docking and quantum chemical calculations
P Pragyan, SS Kesharwani, PP Nandekar, V Rathod, AT Sangamwar
Molecular diversity 18 (4), 865-878, 2014
A review of nanotechnology-based approaches for breast cancer and triple-negative breast cancer
V Jain, H Kumar, HV Anod, P Chand, NV Gupta, S Dey, SS Kesharwani
Journal of Controlled Release, 2020
Characterization of differences in substrate specificity among CYP1A1, CYP1A2 and CYP1B1: an integrated approach employing molecular docking and molecular dynamics simulations
SS Kesharwani, PP Nandekar, P Pragyan, V Rathod, AT Sangamwar
Journal of Molecular Recognition 29 (8), 370-390, 2016
Comparative proteomics among cytochrome p450 family 1 for differential substrate specificity
SS Kesharwani, PP Nandekar, P Pragyan, AT Sangamwar
The protein journal 33 (6), 536-548, 2014
Hydrophobically modified inulin-based micelles: transport mechanisms and drug delivery applications for breast cancer
SS Kesharwani, R Dachineni, GJ Bhat, H Tummala
Journal of Drug Delivery Science and Technology 54, 101254, 2019
Intestinal transport of TRH analogs through PepT1: the role of in silico and in vitro modeling
P Bagul, KS Khomane, SS Kesharwani, P Pragyan, PP Nandekar, ...
Journal of Molecular Recognition 27 (10), 609-617, 2014
Molecular dynamics simulation studies for DNA sequence recognition by reactive metabolites of anticancer compounds
KM Tumbi, PP Nandekar, N Shaikh, SS Kesharwani, AT Sangamwar
Journal of Molecular Recognition 27 (3), 138-150, 2014
Developing polymer-drug complex based toll-like receptor (TLR-2/TLR-4) antagonist for modulating gut innate immune system to prevent/treat IBD and colon cancer
SS Kesharwani, M Rajput, H Tummala
The Journal of Immunology 198 (1 Supplement), 81.20-81.20, 2017
Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer
R Sankaranarayanan, R Dachineni, DR Kumar, E Callegari, ...
Cancer Research 78 (13 Supplement), 2308-2308, 2018
Site specific curcumin-polymer molecular complexes and methods of treating colon diseases and inflammation
H Tummala, S Kesharwani
US Patent App. 15/695,757, 2018
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