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Denes Hnisz
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Master transcription factors and mediator establish super-enhancers at key cell identity genes
WA Whyte, DA Orlando, D Hnisz, BJ Abraham, CY Lin, MH Kagey, ...
Cell 153 (2), 307-319, 2013
37552013
Super-enhancers in the control of cell identity and disease
D Hnisz, BJ Abraham, TI Lee, A Lau, V Saint-André, AA Sigova, HA Hoke, ...
Cell 155 (4), 934-947, 2013
34632013
Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
18652018
A phase separation model for transcriptional control
D Hnisz, K Shrinivas, RA Young, AK Chakraborty, PA Sharp
Cell 169 (1), 13-23, 2017
14552017
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science 351 (6280), 1454-1458, 2016
10272016
Transcriptional addiction in cancer
JE Bradner, D Hnisz, RA Young
Cell 168 (4), 629-643, 2017
10212017
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes
JM Dowen, ZP Fan, D Hnisz, G Ren, BJ Abraham, LN Zhang, ...
Cell 159 (2), 374-387, 2014
9202014
YY1 is a structural regulator of enhancer-promoter loops
AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ...
Cell 171 (7), 1573-1588. e28, 2017
8512017
Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers
D Hnisz, J Schuijers, CY Lin, AS Weintraub, BJ Abraham, TI Lee, ...
Molecular cell 58 (2), 362-370, 2015
4762015
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
4412018
Insulated neighborhoods: structural and functional units of mammalian gene control
D Hnisz, DS Day, RA Young
Cell 167 (5), 1188-1200, 2016
4272016
3D chromosome regulatory landscape of human pluripotent cells
X Ji, DB Dadon, BE Powell, ZP Fan, D Borges-Rivera, S Shachar, ...
Cell stem cell 18 (2), 262-275, 2016
4262016
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
VE Clark, AS Harmancı, H Bai, MW Youngblood, TI Lee, JF Baranoski, ...
Nature genetics 48 (10), 1253-1259, 2016
3132016
Transcriptional dysregulation of MYC reveals common enhancer-docking mechanism
J Schuijers, JC Manteiga, AS Weintraub, DS Day, AV Zamudio, D Hnisz, ...
Cell reports 23 (2), 349-360, 2018
1632018
Unblending of transcriptional condensates in human repeat expansion disease
S Basu, SD Mackowiak, H Niskanen, D Knezevic, V Asimi, S Grosswendt, ...
Cell 181 (5), 1062-1079. e30, 2020
1302020
Transcriptional loops meet chromatin: a dual‐layer network controls white–opaque switching in Candida albicans
D Hnisz, T Schwarzmüller, K Kuchler
Molecular microbiology 74 (1), 1-15, 2009
1242009
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans
D Hnisz, O Majer, IE Frohner, V Komnenovic, K Kuchler
PLoS pathogens 6 (5), e1000889, 2010
1222010
Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms
R Schulte-Sasse, S Budach, D Hnisz, A Marsico
Nature Machine Intelligence 3 (6), 513-526, 2021
1072021
A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequences during Candida albicans Morphogenesis
D Hnisz, AF Bardet, CJ Nobile, A Petryshyn, W Glaser, U Schöck, A Stark, ...
PLoS genetics 8 (12), e1003118, 2012
1012012
TNFα shedding and epidermal inflammation are controlled by Jun proteins
J Guinea-Viniegra, R Zenz, H Scheuch, D Hnisz, M Holcmann, L Bakiri, ...
Genes & development 23 (22), 2663-2674, 2009
932009
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Artículos 1–20