| Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ... Cell 178 (5), 1189-1204. e23, 2019 | 226 | 2019 |
| AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ... Nature neuroscience 20 (10), 1329-1341, 2017 | 216 | 2017 |
| Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes NG Ravindra, MM Alfajaro, V Gasque, NC Huston, H Wan, K Szigeti-Buck, ... PLoS biology 19 (3), e3001143, 2021 | 187 | 2021 |
| Parent stem cells can serve as niches for their daughter cells A Pardo-Saganta, PR Tata, BM Law, B Saez, RDW Chow, M Prabhu, ... Nature 523 (7562), 597-601, 2015 | 174 | 2015 |
| Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms E Song, CM Bartley, RD Chow, TT Ngo, R Jiang, CR Zamecnik, ... Cell Reports Medicine 2 (5), 2021 | 172* | 2021 |
| Nonsteroidal anti-inflammatory drugs dampen the cytokine and antibody response to SARS-CoV-2 infection JS Chen, MM Alfajaro, RD Chow, J Wei, RB Filler, SC Eisenbarth, ... Journal of virology 95 (7), 10.1128/jvi. 00014-21, 2021 | 169* | 2021 |
| In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ... Nature biotechnology 37 (11), 1302-1313, 2019 | 136 | 2019 |
| Myoepithelial cells of submucosal glands can function as reserve stem cells to regenerate airways after injury A Tata, Y Kobayashi, RD Chow, J Tran, A Desai, AJ Massri, TJ McCord, ... Cell stem cell 22 (5), 668-683. e6, 2018 | 129 | 2018 |
| A web tool for the design of prime-editing guide RNAs RD Chow, JS Chen, J Shen, S Chen Nature biomedical engineering 5 (2), 190-194, 2021 | 106 | 2021 |
| Cancer CRISPR screens in vivo RD Chow, S Chen Trends in cancer 4 (5), 349-358, 2018 | 98 | 2018 |
| Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 92 | 2019 |
| Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening G Wang, RD Chow, L Ye, CD Guzman, X Dai, MB Dong, F Zhang, ... Science advances 4 (2), eaao5508, 2018 | 88 | 2018 |
| Developmental history provides a roadmap for the emergence of tumor plasticity PR Tata, RD Chow, SV Saladi, A Tata, A Konkimalla, A Bara, D Montoro, ... Developmental cell 44 (6), 679-693. e5, 2018 | 87 | 2018 |
| CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ... Cancer discovery 10 (12), 1912-1933, 2020 | 82 | 2020 |
| A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell metabolism 34 (4), 595-614. e14, 2022 | 81 | 2022 |
| The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2 RD Chow, M Majety, S Chen Nature Communications, 2020 | 60 | 2020 |
| In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens RD Chow, G Wang, L Ye, A Codina, HR Kim, L Shen, MB Dong, Y Errami, ... Nature methods 16 (5), 405-408, 2019 | 49 | 2019 |
| High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells JS Chen, RD Chow, E Song, T Mao, B Israelow, K Kamath, J Bozekowski, ... Science immunology 7 (68), eabl5652, 2021 | 37* | 2021 |
| Sno-derived RNAs are prevalent molecular markers of cancer immunity RD Chow, S Chen Oncogene 37 (50), 6442-6462, 2018 | 36 | 2018 |
| Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti–PD-1 Immunotherapy in Endometrial Carcinoma RD Chow, T Michaels, S Bellone, TMP Hartwich, E Bonazzoli, A Iwasaki, ... Cancer discovery 13 (2), 312-331, 2023 | 28 | 2023 |
Sidi Chen, PhDYale University (Previous: MIT, Broad Institute, University of Chicago)Verified email at yale.edu
