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D. Thomas Rutkowski
D. Thomas Rutkowski
Department of Anatomy and Cell Biology University of Iowa
Dirección de correo verificada de uiowa.edu - Página principal
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A trip to the ER: coping with stress
DT Rutkowski, RJ Kaufman
Trends in cell biology 14 (1), 20-28, 2004
17652004
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
K Zhang, X Shen, J Wu, K Sakaki, T Saunders, DT Rutkowski, SH Back, ...
Cell 124 (3), 587-599, 2006
9342006
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
DT Rutkowski, SM Arnold, CN Miller, J Wu, J Li, KM Gunnison, K Mori, ...
PLoS biology 4 (11), e374, 2006
9282006
ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
J Wu, DT Rutkowski, M Dubois, J Swathirajan, T Saunders, J Wang, ...
Developmental cell 13 (3), 351-364, 2007
7702007
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
DT Rutkowski, J Wu, SH Back, MU Callaghan, SP Ferris, J Iqbal, R Clark, ...
Developmental cell 15 (6), 829-840, 2008
6502008
That which does not kill me makes me stronger: adapting to chronic ER stress
DT Rutkowski, RJ Kaufman
Trends in biochemical sciences 32 (10), 469-476, 2007
5042007
Regulation of basal cellular physiology by the homeostatic unfolded protein response
DT Rutkowski, RS Hegde
Journal of Cell Biology 189 (5), 783-794, 2010
4372010
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex
J Wu, JL Ruas, JL Estall, KA Rasbach, JH Choi, L Ye, P Boström, HM Tyra, ...
Cell metabolism 13 (2), 160-169, 2011
3512011
The Role of p58IPK in Protecting the Stressed Endoplasmic Reticulum
DT Rutkowski, SW Kang, AG Goodman, JL Garrison, J Taunton, MG Katze, ...
Molecular biology of the cell 18 (9), 3681-3691, 2007
2482007
All roads lead to ATF4
DT Rutkowski, RJ Kaufman
Developmental cell 4 (4), 442-444, 2003
2312003
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway
IH Hassan, MS Zhang, LS Powers, JQ Shao, J Baltrusaitis, DT Rutkowski, ...
Journal of Biological Chemistry 287 (7), 4679-4689, 2012
1722012
Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS
J Wang, GW Farr, CJ Zeiss, DJ Rodriguez-Gil, JH Wilson, K Furtak, ...
Proceedings of the National Academy of Sciences 106 (5), 1392-1397, 2009
1682009
C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver
MR Chikka, DDZ McCabe, HM Tyra, DT Rutkowski
Journal of biological chemistry 288 (6), 4405-4415, 2013
1192013
Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences
AM Arensdorf, D Diedrichs, DT Rutkowski
Frontiers in genetics 4, 256, 2013
912013
ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
D DeZwaan-McCabe, RD Sheldon, MC Gorecki, DF Guo, ER Gansemer, ...
Cell reports 19 (9), 1794-1806, 2017
892017
Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen
DT Rutkowski, CM Ott, JR Polansky, VR Lingappa
Journal of Biological Chemistry 278 (32), 30365-30372, 2003
862003
Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen
DT Rutkowski, CM Ott, JR Polansky, VR Lingappa
Journal of Biological Chemistry 278 (32), 30365-30372, 2003
862003
Substrate-specific regulation of the ribosome–translocon junction by N-terminal signal sequences
DT Rutkowski, VR Lingappa, RS Hegde
Proceedings of the National Academy of Sciences 98 (14), 7823-7828, 2001
862001
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis
D DeZwaan-McCabe, JD Riordan, AM Arensdorf, MS Icardi, AJ Dupuy, ...
PLoS genetics 9 (12), e1003937, 2013
852013
2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines
O Zagorodna, SM Martin, DT Rutkowski, T Kuwana, DR Spitz, ...
Oncogene 31 (22), 2738-2749, 2012
802012
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Artículos 1–20