| Human induced pluripotent stem cell–derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes I Karakikes, M Ameen, V Termglinchan, JC Wu Circulation research 117 (1), 80-88, 2015 | 480 | 2015 |
| Therapeutic Cardiac‐Targeted Delivery of miR‐1 Reverses Pressure Overload–Induced Cardiac Hypertrophy and Attenuates Pathological Remodeling I Karakikes, AH Chaanine, S Kang, BN Mukete, D Jeong, S Zhang, ... Journal of the American Heart Association 2 (2), e000078, 2013 | 352 | 2013 |
| Acute β-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells GM Ellison, D Torella, I Karakikes, S Purushothaman, A Curcio, ... Journal of Biological Chemistry 282 (15), 11397-11409, 2007 | 218 | 2007 |
| Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy I Karakikes, F Stillitano, M Nonnenmacher, C Tzimas, D Sanoudou, ... Nature communications 6 (1), 6955, 2015 | 200 | 2015 |
| Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ... Cell stem cell 20 (4), 490-504. e5, 2017 | 198 | 2017 |
| Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes I Karakikes, GD Senyei, J Hansen, CW Kong, EU Azeloglu, F Stillitano, ... Stem cells translational medicine 3 (1), 18-31, 2014 | 198 | 2014 |
| Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium IC Turnbull, I Karakikes, GW Serrao, P Backeris, JJ Lee, C Xie, G Senyei, ... The FASEB Journal 28 (2), 644, 2014 | 180 | 2014 |
| iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy K Kodo, SG Ong, F Jahanbani, V Termglinchan, K Hirono, ... Nature cell biology 18 (10), 1031-1042, 2016 | 179 | 2016 |
| Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro E Matsa, PW Burridge, KH Yu, JH Ahrens, V Termglinchan, H Wu, C Liu, ... Cell stem cell 19 (3), 311-325, 2016 | 169 | 2016 |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 159 | 2019 |
| Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. A Chen, DK Lieu, L Freschauf, V Lew, H Sharma, J Wang, D Nguyen, ... Advanced materials (Deerfield Beach, Fla.) 23 (48), 5785-5791, 2011 | 152 | 2011 |
| A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes JC Borah, S Mujtaba, I Karakikes, L Zeng, M Muller, J Patel, N Moshkina, ... Chemistry & biology 18 (4), 531-541, 2011 | 152 | 2011 |
| Fetal cells traffic to injured maternal myocardium and undergo cardiac differentiation RJ Kara, P Bolli, I Karakikes, I Matsunaga, J Tripodi, O Tanweer, P Altman, ... Circulation research 110 (1), 82-93, 2012 | 147 | 2012 |
| Passive stretch induces structural and functional maturation of engineered heart muscle as predicted by computational modeling OJ Abilez, E Tzatzalos, H Yang, MT Zhao, G Jung, AM Zöllner, M Tiburcy, ... Stem cells 36 (2), 265-277, 2018 | 144 | 2018 |
| A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells Z Weng, CW Kong, L Ren, I Karakikes, L Geng, J He, MZY Chow, CF Mok, ... Stem cells and development 23 (14), 1704-1716, 2014 | 121 | 2014 |
| Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells E Galende, I Karakikes, L Edelmann, RJ Desnick, T Kerenyi, G Khoueiry, ... Cellular Reprogramming (Formerly" Cloning and Stem Cells") 12 (2), 117-125, 2010 | 119 | 2010 |
| Cardiovascular development: towards biomedical applicability: Resident cardiac stem cells D Torella, GM Ellison, I Karakikes, B Nadal-Ginard Cellular and molecular life sciences 64, 661-673, 2007 | 115 | 2007 |
| A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay T Seeger, R Shrestha, CK Lam, C Chen, WL McKeithan, E Lau, ... Circulation 139 (6), 799-811, 2019 | 106 | 2019 |
| Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells F Stillitano, J Hansen, CW Kong, I Karakikes, C Funck-Brentano, L Geng, ... Elife 6, e19406, 2017 | 96 | 2017 |
| Myocyte death and renewal: modern concepts of cardiac cellular homeostasis GM Ellison, D Torella, I Karakikes, B Nadal-Ginard Nature Clinical Practice Cardiovascular Medicine 4 (Suppl 1), S52-S59, 2007 | 95 | 2007 |
