| Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression B Phipson, S Lee, IJ Majewski, WS Alexander, GK Smyth The annals of applied statistics 10 (2), 946, 2016 | 895 | 2016 |
| SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ... Cancer cell 27 (5), 617-630, 2015 | 600 | 2015 |
| Therapeutic targeting of splicing in cancer SCW Lee, O Abdel-Wahab Nature medicine 22 (9), 976-986, 2016 | 521 | 2016 |
| BET inhibitor resistance emerges from leukaemia stem cells CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ... Nature 525 (7570), 538-542, 2015 | 510 | 2015 |
| H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers M Seiler, A Yoshimi, R Darman, B Chan, G Keaney, M Thomas, ... Nature medicine 24 (4), 497-504, 2018 | 466 | 2018 |
| Diverse and targetable kinase alterations drive histiocytic neoplasms EL Diamond, BH Durham, J Haroche, Z Yao, J Ma, SA Parikh, Z Wang, ... Cancer discovery 6 (2), 154-165, 2016 | 444 | 2016 |
| Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ... Nature medicine 22 (6), 672-678, 2016 | 358 | 2016 |
| Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 248 | 2019 |
| Therapeutic targeting of RNA splicing catalysis through inhibition of protein arginine methylation JY Fong, L Pignata, PA Goy, KC Kawabata, SCW Lee, CM Koh, D Musiani, ... Cancer cell 36 (2), 194-209. e9, 2019 | 212 | 2019 |
| Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ... Cancer cell 34 (2), 225-241. e8, 2018 | 208 | 2018 |
| DNA methylation disruption reshapes the hematopoietic differentiation landscape F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ... Nature genetics 52 (4), 378-387, 2020 | 196 | 2020 |
| Spliceosomal disruption of the non-canonical BAF complex in cancer D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ... Nature 574 (7778), 432-436, 2019 | 182 | 2019 |
| Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 177 | 2019 |
| Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of clinical investigation 130 (2), 981-997, 2020 | 163 | 2020 |
| Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices J Lipski, TIH Park, D Li, SCW Lee, AJ Trevarton, KKH Chung, ... Brain research 1077 (1), 187-199, 2006 | 151 | 2006 |
| Recurrent CDKN1B (p27) mutations in hairy cell leukemia S Dietrich, J Hüllein, SCW Lee, B Hutter, D Gonzalez, S Jayne, MJS Dyer, ... Blood, The Journal of the American Society of Hematology 126 (8), 1005-1008, 2015 | 96 | 2015 |
| Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis SCW Lee, S Miller, C Hyland, M Kauppi, M Lebois, L Di Rago, D Metcalf, ... Blood, The Journal of the American Society of Hematology 126 (2), 167-175, 2015 | 87 | 2015 |
| Mutations in the RNA splicing factor SF3B1 promote tumorigenesis through MYC stabilization Z Liu, A Yoshimi, J Wang, H Cho, S Chun-Wei Lee, M Ki, L Bitner, T Chu, ... Cancer Discovery 10 (6), 806-821, 2020 | 84 | 2020 |
| Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML A Yoshimi, ME Balasis, A Vedder, K Feldman, Y Ma, H Zhang, SCW Lee, ... Blood, The Journal of the American Society of Hematology 130 (4), 397-407, 2017 | 81 | 2017 |
| A non‐canonical function of Ezh2 preserves immune homeostasis A Vasanthakumar, D Xu, ATL Lun, AJ Kueh, KPJM van Gisbergen, ... EMBO reports 18 (4), 619-631, 2017 | 78 | 2017 |
