| Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription T Shimohata, T Nakajima, M Yamada, C Uchida, O Onodera, S Naruse, ... Nature genetics 26 (1), 29-36, 2000 | 489 | 2000 |
| A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease? R Koide, S Kobayashi, T Shimohata, T Ikeuchi, M Maruyama, M Saito, ... Human molecular genetics 8 (11), 2047-2053, 1999 | 457 | 1999 |
| Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch S Igarashi, R Koide, T Shimohata, M Yamada, Y Hayashi, H Takano, ... Nature genetics 18 (2), 111-117, 1998 | 415 | 1998 |
| Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats H Zhao, T Shimohata, JQ Wang, G Sun, DW Schaal, RM Sapolsky, ... Journal of Neuroscience 25 (42), 9794-9806, 2005 | 352 | 2005 |
| Microglia and monocytes/macrophages polarization reveal novel therapeutic mechanism against stroke M Kanazawa, I Ninomiya, M Hatakeyama, T Takahashi, T Shimohata International journal of molecular sciences 18 (10), 2135, 2017 | 347 | 2017 |
| Close associations between prevalences of dominantly inherited spinocerebellar ataxias with CAG-repeat expansions and frequencies of large normal CAG alleles in Japanese and … H Takano, G Cancel, T Ikeuchi, D Lorenzetti, R Mawad, G Stevanin, ... The American Journal of Human Genetics 63 (4), 1060-1066, 1998 | 260 | 1998 |
| Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial M Katsuno, H Banno, K Suzuki, Y Takeuchi, M Kawashima, I Yabe, ... The Lancet Neurology 9 (9), 875-884, 2010 | 187 | 2010 |
| Cerebellar involvement in progressive supranuclear palsy: a clinicopathological study M Kanazawa, T Shimohata, Y Toyoshima, M Tada, A Kakita, T Morita, ... Movement disorders: official journal of the Movement Disorder Society 24 (9 …, 2009 | 141 | 2009 |
| Huntington's disease–like 2 (HDL2) in North America and Japan RL Margolis, SE Holmes, A Rosenblatt, L Gourley, E O'Hearn, CA Ross, ... Annals of Neurology: Official Journal of the American Neurological …, 2004 | 140 | 2004 |
| Symptomatic narcolepsy in patients with neuromyelitis optica and multiple sclerosis: new neurochemical and immunological implications T Kanbayashi, T Shimohata, I Nakashima, H Yaguchi, I Yabe, ... Archives of neurology 66 (12), 1563-1566, 2009 | 131 | 2009 |
| Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA … T Sato, M Oyake, K Nakamura, K Nakao, Y Fukusima, O Onodera, ... Human molecular genetics 8 (1), 99-106, 1999 | 128 | 1999 |
| Clinical characteristics of autoimmune GFAP astrocytopathy A Kimura, A Takekoshi, N Yoshikura, Y Hayashi, T Shimohata Journal of neuroimmunology 332, 91-98, 2019 | 123 | 2019 |
| Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke M Kanazawa, K Kawamura, T Takahashi, M Miura, Y Tanaka, M Koyama, ... Brain 138 (7), 1932-1948, 2015 | 121 | 2015 |
| Daytime hypoxemia, sleep-disordered breathing, and laryngopharyngeal findings in multiple system atrophy T Shimohata, H Shinoda, H Nakayama, T Ozawa, K Terajima, ... Archives of Neurology 64 (6), 856-861, 2007 | 121 | 2007 |
| Angiogenesis in the ischemic core: A potential treatment target? M Kanazawa, T Takahashi, M Ishikawa, O Onodera, T Shimohata, ... Journal of Cerebral Blood Flow & Metabolism 39 (5), 753-769, 2019 | 120 | 2019 |
| Reduction rate of body mass index predicts prognosis for survival in amyotrophic lateral sclerosis: a multicenter study in Japan T Shimizu, U Nagaoka, Y Nakayama, A Kawata, C Kugimoto, Y Kuroiwa, ... Amyotrophic Lateral Sclerosis 13 (4), 363-366, 2012 | 118 | 2012 |
| COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion M Hayashi, Y Sahashi, Y Baba, H Okura, T Shimohata Journal of the neurological sciences 415, 2020 | 115 | 2020 |
| Atrophy of the cerebellum and brainstem in dentatorubral pallidoluysian atrophy: influence of CAG repeat size on MRI findings R Koide, O Onodera, T Ikeuchi, R Kondo, H Tanaka, S Tokiguchi, ... Neurology 49 (6), 1605-1612, 1997 | 106 | 1997 |
| Frequency of nocturnal sudden death in patients with multiple system atrophy T Shimohata, T Ozawa, H Nakayama, M Tomita, H Shinoda, M Nishizawa Journal of neurology 255, 1483-1485, 2008 | 105 | 2008 |
| Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease K Kasuga, T Shimohata, A Nishimura, A Shiga, T Mizuguchi, J Tokunaga, ... Journal of Neurology, Neurosurgery & Psychiatry 80 (9), 1050-1052, 2009 | 103 | 2009 |
