| IDO1 in cancer: a Gemini of immune checkpoints L Zhai, E Ladomersky, A Lenzen, B Nguyen, R Patel, KL Lauing, M Wu, ... Cellular & molecular immunology 15 (5), 447-457, 2018 | 305 | 2018 |
| Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy L Zhai, S Spranger, DC Binder, G Gritsina, KL Lauing, FJ Giles, ... Clinical cancer research 21 (24), 5427-5433, 2015 | 289 | 2015 |
| Metabolically activated adipose tissue macrophages perform detrimental and beneficial functions during diet-induced obesity BR Coats, KQ Schoenfelt, VC Barbosa-Lorenzi, E Peris, C Cui, A Hoffman, ... Cell reports 20 (13), 3149-3161, 2017 | 258 | 2017 |
| IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma E Ladomersky, L Zhai, A Lenzen, KL Lauing, J Qian, DM Scholtens, ... Clinical cancer research 24 (11), 2559-2573, 2018 | 165 | 2018 |
| Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival L Zhai, E Ladomersky, KL Lauing, M Wu, M Genet, G Gritsina, B Győrffy, ... Clinical Cancer Research 23 (21), 6650-6660, 2017 | 146 | 2017 |
| Immunosuppressive IDO in cancer: mechanisms of action, animal models, and targeting strategies L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, JA Sosman, B Zhang, ... Frontiers in immunology 11, 1185, 2020 | 144 | 2020 |
| Hepatitis E virus genotyping based on full-length genome and partial genomic regions L Zhai, X Dai, J Meng Virus Research 120 (1-2), 57-69, 2006 | 139 | 2006 |
| The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma E Ladomersky, DM Scholtens, M Kocherginsky, EA Hibler, ET Bartom, ... Frontiers in pharmacology 10, 200, 2019 | 112 | 2019 |
| The role of IDO in brain tumor immunotherapy L Zhai, KL Lauing, AL Chang, M Dey, J Qian, Y Cheng, MS Lesniak, ... Journal of neuro-oncology 123, 395-403, 2015 | 100 | 2015 |
| Advanced age increases immunosuppression in the brain and decreases immunotherapeutic efficacy in subjects with glioblastoma E Ladomersky, L Zhai, KL Lauing, A Bell, J Xu, M Kocherginsky, B Zhang, ... Clinical Cancer Research 26 (19), 5232-5245, 2020 | 69 | 2020 |
| The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy L Zhai, M Dey, KL Lauing, G Gritsina, R Kaur, RV Lukas, MK Nicholas, ... Journal of Clinical Neuroscience 22 (12), 1964-1968, 2015 | 67 | 2015 |
| Tumor cell IDO enhances immune suppression and decreases survival independent of tryptophan metabolism in glioblastoma L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, B Nguyen, M Genet, ... Clinical cancer research 27 (23), 6514-6528, 2021 | 60 | 2021 |
| Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma L Zhai, E Ladomersky, CR Dostal, KL Lauing, K Swoap, LK Billingham, ... Brain, behavior, and immunity 62, 24-29, 2017 | 54 | 2017 |
| An RNA aptamer-based microcantilever sensor to detect the inflammatory marker, mouse lipocalin-2 L Zhai, T Wang, K Kang, Y Zhao, P Shrotriya, M Nilsen-Hamilton Analytical chemistry 84 (20), 8763-8770, 2012 | 36 | 2012 |
| A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors S Otto-Meyer, R DeFaccio, C Dussold, E Ladomersky, L Zhai, KL Lauing, ... Brain, Behavior, & Immunity-Health 2, 100025, 2020 | 31 | 2020 |
| Fusion of C3d molecule with neutralization epitope (s) of hepatitis E virus enhances antibody avidity maturation and neutralizing activity following DNA immunization S Yang, C Wang, X Fang, L Zhai, C Dong, L Ding, J Meng, L Wang Virus research 151 (2), 162-169, 2010 | 30 | 2010 |
| Advanced age negatively impacts survival in an experimental brain tumor model E Ladomersky, L Zhai, G Gritsina, M Genet, KL Lauing, M Wu, CD James, ... Neuroscience letters 630, 203-208, 2016 | 28 | 2016 |
| The interplay among psychological distress, the immune system, and brain tumor patient outcomes S Otto-Meyer, J Lumibao, E Kim, E Ladomersky, L Zhai, KL Lauing, ... Current opinion in behavioral sciences 28, 44-50, 2019 | 26 | 2019 |
| Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry TT Nguyen, DH Shin, S Sohoni, SK Singh, Y Rivera-Molina, H Jiang, ... Journal for immunotherapy of cancer 10 (7), 2022 | 25 | 2022 |
| Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma DC Binder, E Ladomersky, A Lenzen, L Zhai, KL Lauing, SD Otto-Meyer, ... Translational cancer research 7 (Suppl 4), S510, 2018 | 24 | 2018 |
