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Mohamad Hamieh
Mohamad Hamieh
Assistant Professor, Weill Cornell Medicine
Dirección de correo verificada de med.cornell.edu
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Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
J Eyquem, J Mansilla-Soto, T Giavridis, SJC van der Stegen, M Hamieh, ...
Nature 543 (7643), 113-117, 2017
16912017
CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
T Giavridis, SJC van der Stegen, J Eyquem, M Hamieh, A Piersigilli, ...
Nature medicine 24 (6), 731-738, 2018
10632018
Integrative analyses of colorectal cancer show immunoscore is a stronger predictor of patient survival than microsatellite instability
B Mlecnik, G Bindea, HK Angell, P Maby, M Angelova, D Tougeron, ...
Immunity 44 (3), 698-711, 2016
9612016
The pharmacology of second-generation chimeric antigen receptors
SJC Van Der Stegen, M Hamieh, M Sadelain
Nature reviews Drug discovery 14 (7), 499-509, 2015
5482015
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
M Hamieh, A Dobrin, A Cabriolu, SJC van der Stegen, T Giavridis, ...
Nature 568 (7750), 112-116, 2019
4822019
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency
J Feucht, J Sun, J Eyquem, YJ Ho, Z Zhao, J Leibold, A Dobrin, A Cabriolu, ...
Nature medicine 25 (1), 82-88, 2019
4162019
Integrating proteomics and transcriptomics for systematic combinatorial chimeric antigen receptor therapy of AML
F Perna, SH Berman, RK Soni, J Mansilla-Soto, J Eyquem, M Hamieh, ...
Cancer cell 32 (4), 506-519. e5, 2017
2722017
Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized …
P Maby, D Tougeron, M Hamieh, B Mlecnik, H Kora, G Bindea, HK Angell, ...
Cancer research 75 (17), 3446-3455, 2015
2692015
Low-dose radiation conditioning enables CAR T cells to mitigate antigen escape
C DeSelm, ML Palomba, J Yahalom, M Hamieh, J Eyquem, ...
Molecular Therapy 26 (11), 2542-2552, 2018
1902018
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools
O Soukarieh, P Gaildrat, M Hamieh, A Drouet, S Baert-Desurmont, ...
PLoS genetics 12 (1), e1005756, 2016
1722016
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic …
J Feucht, S Kayser, D Gorodezki, M Hamieh, M Döring, F Blaeschke, ...
Oncotarget 7 (47), 76902, 2016
1662016
Immunogenicity of CAR T cells in cancer therapy
DL Wagner, E Fritsche, MA Pulsipher, N Ahmed, M Hamieh, M Hegde, ...
Nature reviews Clinical oncology 18 (6), 379-393, 2021
1632021
HLA-independent T cell receptors for targeting tumors with low antigen density
J Mansilla-Soto, J Eyquem, S Haubner, M Hamieh, J Feucht, N Paillon, ...
Nature medicine 28 (2), 345-352, 2022
882022
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells
SJC van der Stegen, PL Lindenbergh, RM Petrovic, H Xie, MP Diop, ...
Nature biomedical engineering 6 (11), 1284-1297, 2022
342022
Programming CAR T cell tumor recognition: tuned antigen sensing and logic gating
M Hamieh, J Mansilla-Soto, I Rivière, M Sadelain
Cancer Discovery 13 (4), 829-843, 2023
282023
Artificial antigen‐presenting cells expressing HLA class II molecules as an effective tool for amplifying human specific memory CD4+ T cells
A Garnier, M Hamieh, A Drouet, J Leprince, D Vivien, T Frébourg, ...
Immunology and Cell Biology 94 (7), 662-672, 2016
212016
Ferromagnetism and magnetoresistance of nanocomposite ZnO-Co thin films
M Hamieh, N Jedrecy, C Hebert, D Demaille, J Perriere
Physical Review B 92 (15), 155302, 2015
192015
The ADAMTS131239–1253 peptide is a dominant HLA-DR1-restricted CD4+ T-cell epitope
L Gilardin, S Delignat, I Peyron, M Ing, YC Lone, B Gangadharan, ...
haematologica 102 (11), 1833, 2017
162017
Sizing of the physical layer of a rf intra-chip communications
M Hamieh, M Ariaudo, S Quintanel, Y Louët
2014 21st IEEE International Conference on Electronics, Circuits and Systems …, 2014
152014
CD19 CAR antigen engagement mechanisms and affinity tuning
C He, J Mansilla-Soto, N Khanra, M Hamieh, V Bustos, AJ Paquette, ...
Science immunology 8 (81), eadf1426, 2023
132023
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Artículos 1–20