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Pedro J. Real
Pedro J. Real
Associate Professor Biochemistry and Molecular Biology. University of Granada/GENyO
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ...
Nature medicine 13 (10), 1203-1210, 2007
10352007
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
10232006
γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
PJ Real, V Tosello, T Palomero, M Castillo, E Hernando, E De Stanchina, ...
Nature medicine 15 (1), 50-58, 2009
4932009
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection
I Gutierrez-Aranda, V Ramos-Mejia, C Bueno, M Munoz-Lopez, PJ Real, ...
Stem cells 28 (9), 1568-1570, 2010
4082010
Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
PJ Real, A Sierra, A De Juan, JC Segovia, JM Lopez-Vega, ...
Oncogene 21 (50), 7611-7618, 2002
3942002
Cannabinoid receptors as novel targets for the treatment of melanoma
C Blázquez, A Carracedo, L Barrado, P José Real, ...
The FASEB journal 20 (14), 2633-2635, 2006
3262006
CUTLL1, a novel human T-cell lymphoma cell line with t (7; 9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors
T Palomero, KC Barnes, PJ Real, JL Glade Bender, ML Sulis, VV Murty, ...
Leukemia 20 (7), 1279-1287, 2006
1742006
The TLX1 oncogene drives aneuploidy in T cell transformation
K De Keersmaecker, PJ Real, GD Gatta, T Palomero, ML Sulis, V Tosello, ...
Nature medicine 16 (11), 1321-1327, 2010
1692010
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL
ML Sulis, O Williams, T Palomero, V Tosello, S Pallikuppam, PJ Real, ...
Blood, The Journal of the American Society of Hematology 112 (3), 733-740, 2008
1692008
NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia
PJ Real, AA Ferrando
Leukemia 23 (8), 1374-1377, 2009
1632009
Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory …
L Sánchez, I Gutierrez-Aranda, G Ligero, R Rubio, M Muñoz-López, ...
Stem cells 29 (2), 251-262, 2011
1542011
WT1 mutations in T-ALL
V Tosello, MR Mansour, K Barnes, M Paganin, ML Sulis, S Jenkinson, ...
Blood, The Journal of the American Society of Hematology 114 (5), 1038-1045, 2009
1492009
Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2
PJ Real, Y Cao, R Wang, Z Nikolovska-Coleska, J Sanz-Ortiz, S Wang, ...
Cancer research 64 (21), 7947-7953, 2004
1372004
HOXA9 promotes hematopoietic commitment of human embryonic stem cells
V Ramos-Mejía, O Navarro-Montero, V Ayllón, C Bueno, T Romero, ...
Blood, The Journal of the American Society of Hematology 124 (20), 3065-3075, 2014
1102014
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors
V Ramos-Mejía, R Montes, C Bueno, V Ayllón, PJ Real, R Rodríguez, ...
PloS one 7 (4), e35824, 2012
882012
SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells
PJ Real, G Ligero, V Ayllon, V Ramos-Mejia, C Bueno, I Gutierrez-Aranda, ...
Molecular Therapy 20 (7), 1443-1453, 2012
802012
Blockade of epidermal growth factor receptors chemosensitizes breast cancer cells through up-regulation of Bnip3L
PJ Real, A Benito, J Cuevas, MT Berciano, A de Juan, P Coffer, ...
Cancer research 65 (18), 8151-8157, 2005
792005
Nodal/Activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage
V Ramos-Mejia, GJ Melen, L Sanchez, I Gutierrez-Aranda, G Ligero, ...
Molecular Therapy 18 (12), 2173-2181, 2010
732010
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification
C Bueno, R Montes, GJ Melen, V Ramos-Mejia, PJ Real, V Ayllón, ...
Cell research 22 (6), 986-1002, 2012
612012
The Notch ligand DLL4 specifically marks human hematoendothelial progenitors and regulates their hematopoietic fate
V Ayllon, C Bueno, V Ramos-Mejia, O Navarro-Montero, C Prieto, PJ Real, ...
Leukemia 29 (8), 1741-1753, 2015
602015
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Artículos 1–20