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Katherine Holzem
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Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine
S Rajamani, LL Eckhardt, CR Valdivia, CA Klemens, BM Gillman, ...
British journal of pharmacology 149 (5), 481-489, 2006
2352006
Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome
AS Amin, LJ Herfst, BP Delisle, CA Klemens, MB Rook, CR Bezzina, ...
The Journal of clinical investigation 118 (7), 2552-2561, 2008
1142008
Arrhythmogenic Remodeling of β2 Versus β1 Adrenergic Signaling in the Human Failing Heart
D Lang, K Holzem, C Kang, M Xiao, HJ Hwang, GA Ewald, KA Yamada, ...
Circulation: Arrhythmia and Electrophysiology 8 (2), 409-419, 2015
992015
Associations between clinical diagnostic criteria and pretreatment patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic …
J Balderman, K Holzem, BJ Field, MM Bottros, AA Abuirqeba, C Vemuri, ...
Journal of Vascular Surgery 66 (2), 533-544. e2, 2017
652017
Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure
KM Holzem, JF Gomez, AV Glukhov, EJ Madden, AC Koppel, GA Ewald, ...
Journal of molecular and cellular cardiology 96, 82-92, 2016
472016
Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease
B Hsueh, VM Burns, P Pauerstein, K Holzem, L Ye, K Engberg, AC Wang, ...
Scientific reports 7 (1), 5899, 2017
382017
Right ventricular arrhythmogenesis in failing human heart: the role of conduction and repolarization remodeling
Q Lou, DL Janks, KM Holzem, D Lang, B Onal, CM Ambrosi, VV Fedorov, ...
American Journal of Physiology-Heart and Circulatory Physiology 303 (12 …, 2012
362012
Three-dimensional printing physiology laboratory technology
MS Sulkin, E Widder, C Shao, KM Holzem, C Gloschat, SR Gutbrod, ...
American Journal of Physiology-Heart and Circulatory Physiology 305 (11 …, 2013
292013
Adverse remodeling of the electrophysiological response to ischemia–reperfusion in human heart failure is associated with remodeling of metabolic gene expression
FS Ng, KM Holzem, AC Koppel, D Janks, F Gordon, AL Wit, NS Peters, ...
Circulation: Arrhythmia and Electrophysiology 7 (5), 875-882, 2014
262014
Arrhythmogenic remodelling of activation and repolarization in the failing human heart
KM Holzem, IR Efimov
Europace 14 (suppl_5), v50-v57, 2012
262012
Properties of WT and mutant hERG K+ channels expressed in neonatal mouse cardiomyocytes
EC Lin, KM Holzem, BD Anson, BM Moungey, SY Balijepalli, DJ Tester, ...
American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010
242010
Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts
KM Holzem, KC Vinnakota, VK Ravikumar, EJ Madden, GA Ewald, ...
The FASEB journal 30 (8), 2698, 2016
232016
Arrhythmogenic and metabolic remodelling of failing human heart
CR Gloschat, AC Koppel, KK Aras, JA Brennan, KM Holzem, IR Efimov
The Journal of Physiology 594 (14), 3963-3980, 2016
202016
Diet‐induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload
KM Holzem, JT Marmerstein, EJ Madden, IR Efimov
Physiological reports 3 (8), e12489, 2015
202015
Nanoscale three-dimensional imaging of the human myocyte
MS Sulkin, F Yang, KM Holzem, B Van Leer, C Bugge, JI Laughner, ...
Journal of structural biology 188 (1), 55-60, 2014
162014
Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation
KM Holzem, EJ Madden, IR Efimov
Europace 16 (suppl_4), iv77-iv85, 2014
72014
The role of IKr in transmural repolarization abnormalities in human heart failure
KM Holzem, AV Glukhov, IR Efimov
Circulation 124 (suppl_21), A16014-A16014, 2011
72011
Surgical planning with three-dimensional printing of a complex renal artery aneurysm
KM Holzem, S Jayarajan, MA Zayed
Journal of Vascular Surgery Cases, Innovations and Techniques 4 (1), 19, 2018
62018
New cardiac magnetic resonance imaging modalities aid in the detection of myocardial fibrosis
KM Holzem
Physiological Reports 5 (6), 2017
12017
Remodeling of Energetics and Electrophysiology in Cardiac Hypertrophy and Failure: from Function to Structure
KM Holzem
Washington University in St. Louis, 2017
12017
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