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Zhengxin (Jason) Cai
Zhengxin (Jason) Cai
Associate Professor of Radiology & Biomedical Imaging, Pharmacology, Yale University
Dirección de correo verificada de yale.edu - Página principal
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PET imaging of synaptic density: a new tool for investigation of neuropsychiatric diseases
Z Cai, S Li, D Matuskey, N Nabulsi, Y Huang
Neuroscience letters 691, 44-50, 2019
1082019
Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals
Z Cai, CJ Anderson
Journal of labelled compounds and radiopharmaceuticals 57 (4), 224-230, 2014
812014
Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
S Li, Z Cai, X Wu, D Holden, R Pracitto, M Kapinos, H Gao, D Labaree, ...
ACS chemical neuroscience 10 (3), 1544-1554, 2018
772018
First-in-human evaluation of 18F-SynVesT-1, a radioligand for PET imaging of synaptic vesicle glycoprotein 2A
M Naganawa, S Li, N Nabulsi, S Henry, MQ Zheng, R Pracitto, Z Cai, ...
Journal of Nuclear Medicine 62 (4), 561-567, 2021
642021
In vivo synaptic density imaging with 11C-UCB-J detects treatment effects of saracatinib in a mouse model of Alzheimer disease
T Toyonaga, LM Smith, SJ Finnema, JD Gallezot, M Naganawa, J Bini, ...
Journal of Nuclear Medicine 60 (12), 1780-1786, 2019
632019
New cross-bridged cyclam derivative CB-TE1K1P, an improved bifunctional chelator for copper radionuclides
D Zeng, Q Ouyang, Z Cai, XQ Xie, CJ Anderson
Chemical communications 50 (1), 43-45, 2014
512014
PET imaging for early detection of Alzheimer’s disease: from pathologic to physiologic biomarkers
W Bao, H Jia, S Finnema, Z Cai, RE Carson, YH Huang
PET clinics 12 (3), 329-350, 2017
492017
In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced …
NE Boutagy, J Wu, Z Cai, W Zhang, CJ Booth, TC Kyriakides, D Pfau, ...
JACC: Basic to Translational Science 3 (3), 378-390, 2018
482018
Approaches to PET imaging of glioblastoma
LR Drake, AT Hillmer, Z Cai
Molecules 25 (3), 568, 2020
452020
64Cu-Labeled Somatostatin Analogues Conjugated with Cross-Bridged Phosphonate-Based Chelators via Strain-Promoted Click Chemistry for PET Imaging: In …
Z Cai, Q Ouyang, D Zeng, KN Nguyen, J Modi, L Wang, AG White, ...
Journal of medicinal chemistry 57 (14), 6019-6029, 2014
452014
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q
J Spurrier, LS Nicholson, XT Fang, AJ Stoner, T Toyonaga, D Holden, ...
Science translational medicine 14 (647), eabi8593, 2022
432022
Comparison of conjugation strategies of cross-bridged macrocyclic chelators with cetuximab for copper-64 radiolabeling and PET imaging of EGFR in colorectal tumor-bearing mice
D Zeng, Y Guo, AG White, Z Cai, J Modi, R Ferdani, CJ Anderson
Molecular pharmaceutics 11 (11), 3980-3987, 2014
422014
Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)
S Li, Z Cai, W Zhang, D Holden, S Lin, SJ Finnema, A Shirali, J Ropchan, ...
European journal of nuclear medicine and molecular imaging 46, 1952-1965, 2019
412019
CH activation in S-alkenyl sulfoximines: an endo 1, 5-hydrogen migration.
X Gao, V Gaddam, E Altenhofer, RR Tata, Z Cai, N Yongpruksa, ...
Angewandte Chemie (International ed. in English) 51 (28), 7016-7019, 2012
402012
Total synthesis of the terpenoid buddledone A: 11-membered ring-closing metathesis
Z Cai, N Yongpruksa, M Harmata
Organic letters 14 (7), 1661-1663, 2012
402012
Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2
Z Cai, S Li, W Zhang, R Pracitto, X Wu, E Baum, SJ Finnema, D Holden, ...
ACS chemical neuroscience 11 (4), 592-603, 2020
392020
Studies directed toward the synthesis of hamigeran b: a catalytic oxidative cyclization
Z Cai, M Harmata
Organic Letters 12 (24), 5668-5670, 2010
372010
Imaging mechanisms of disease progression in multiple sclerosis: beyond brain atrophy
F Bagnato, SA Gauthier, C Laule, GRW Moore, R Bove, Z Cai, ...
Journal of Neuroimaging 30 (3), 251-266, 2020
362020
Novel 18F-labeled κ-opioid receptor antagonist as PET radiotracer: synthesis and in vivo evaluation of 18F-LY2459989 in nonhuman primates
S Li, Z Cai, MQ Zheng, D Holden, M Naganawa, SF Lin, J Ropchan, ...
Journal of Nuclear Medicine 59 (1), 140-146, 2018
292018
Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A
S Li, M Naganawa, R Pracitto, S Najafzadeh, D Holden, S Henry, ...
European Journal of Nuclear Medicine and Molecular Imaging 48, 1327-1338, 2021
282021
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