Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance DE Francés, O Motiño, N Agrá, Á González-Rodríguez, ... Diabetes 64 (5), 1522-1531, 2015 | 62 | 2015 |
Protective role of hepatocyte cyclooxygenase‐2 expression against liver ischemia–reperfusion injury in mice O Motiño, DE Francés, N Casanova, M Fuertes‐Agudo, C Cucarella, ... Hepatology 70 (2), 650-665, 2019 | 56 | 2019 |
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p R Brea, O Motiño, D Francés, C García-Monzón, J Vargas, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (2), 325-337, 2018 | 50 | 2018 |
Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice O Motiño, N Agra, RB Contreras, M Domínguez-Moreno, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016 | 50 | 2016 |
Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver is DEAD-Box Helicase p68 (DDX5) Dependent: role in insulin signaling O Motiño, DE Francés, R Mayoral, L Castro-Sánchez, ... Molecular and Cellular Biology 35 (14), 2554-2567, 2015 | 47 | 2015 |
Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells N Agra Andrieu, O Motino, R Mayoral, C Llorente Izquierdo, ... PLoS One 7 (11), e50935, 2012 | 47 | 2012 |
Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet F Lambertucci, A Arboatti, MG Sedlmeier, O Motiño, M de Luján Alvarez, ... The Journal of nutritional biochemistry 58, 17-27, 2018 | 26 | 2018 |
Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis F Lambertucci, O Motiño, S Villar, JP Rigalli, M de Luján Alvarez, ... Toxicology and applied pharmacology 315, 12-22, 2017 | 19 | 2017 |
Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma L Castro-Sánchez, N Agra, CL Izquierdo, O Motiño, M Casado, L Boscá, ... The International Journal of Biochemistry & Cell Biology 45 (11), 2501-2511, 2013 | 19 | 2013 |
Effects of acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI) on body mass index A Joseph, H Chen, G Anagnostopoulos, L Montégut, A Lafarge, O Motiño, ... Cell Death & Disease 12 (6), 599, 2021 | 18 | 2021 |
ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis O Motiño, F Lambertucci, G Anagnostopoulos, S Li, J Nah, F Castoldi, ... Proceedings of the National Academy of Sciences 119 (41), e2207344119, 2022 | 13 | 2022 |
Full-spectrum CARS microscopy of cells and tissues with ultrashort white-light continuum pulses F Vernuccio, R Vanna, C Ceconello, A Bresci, F Manetti, S Sorrentino, ... The Journal of Physical Chemistry B 127 (21), 4733-4745, 2023 | 9 | 2023 |
High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP L Montégut, A Joseph, H Chen, M Abdellatif, C Ruckenstuhl, O Motiño, ... Aging Cell 22 (1), e13751, 2023 | 9 | 2023 |
Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects V Sica, I Martins, O Motiño, JM Bravo-San Pedro, G Kroemer Adipocyte 9 (1), 116-119, 2020 | 8 | 2020 |
An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABAA receptor G Anagnostopoulos, O Motiño, S Li, V Carbonnier, H Chen, V Sica, ... Cell death & disease 13 (4), 356, 2022 | 7 | 2022 |
Paradoxical implication of BAX/BAK in the persistence of tetraploid cells J Deng, LG Gutiérrez, G Stoll, O Motiño, I Martins, L Núñez, ... Cell Death & Disease 12 (11), 1039, 2021 | 7 | 2021 |
Involvement of Bcl-2 Family Proteins in Tetraploidization-Related Senescence D Barriuso, L Alvarez-Frutos, L Gonzalez-Gutierrez, O Motiño, G Kroemer, ... International Journal of Molecular Sciences 24 (7), 6374, 2023 | 5 | 2023 |
Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin L Montegut, H Chen, JM Bravo-San Pedro, O Motiño, I Martins, G Kroemer STAR protocols 3 (1), 101095, 2022 | 4 | 2022 |
Acyl coenzyme A binding protein (ACBP): An aging‐and disease‐relevant “autophagy checkpoint” L Montégut, M Abdellatif, O Motiño, F Madeo, I Martins, V Quesada, ... Aging Cell 22 (9), e13910, 2023 | 3 | 2023 |
Cardio-, hepato-and pneumoprotective effects of autophagy checkpoint inhibition by targeting DBI/ACBP O Motiño, F Lambertucci, G Anagnostopoulos, S Li, I Martins, G Kroemer Autophagy 19 (5), 1604-1606, 2023 | 3 | 2023 |