Mohammad Parvez Alam, PhD
Mohammad Parvez Alam, PhD
Glenn/AFAR Research Fellow; Harvard Medical School
Correu electrònic verificat a hms.harvard.edu - Pàgina d'inici
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The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the …
S Kendrick, HJ Kang, MP Alam, MM Madathil, P Agrawal, V Gokhale, ...
Journal of the American Chemical Society 136 (11), 4161-4171, 2014
1672014
Relationship between structure, entropy and diffusivity in water and water-like liquids
M Agarwal, M Singh, R Sharma, MP Alam, C Chakravarty
Journal of Physical Chemistry B 114 (20), 6995-7001, 2010
872010
Thermodynamic, diffusional, and structural anomalies in rigid-body water models
M Agarwal, MP Alam, C Chakravarty
The Journal of Physical Chemistry B 115 (21), 6935-6945, 2011
682011
Cyanotryptophans as novel fluorescent probes for studying protein conformational changes and DNA–protein interaction
P Talukder, S Chen, B Roy, P Yakovchuk, MM Spiering, MP Alam, ...
Biochemistry 54 (51), 7457-7469, 2015
422015
Interaction of Individual Structural Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA
BR , Poulami Talukder, Hyun-Jin Kang, Shujian Sean Tsuen, Mohammad P. Alam ...
J. Am. Chem. Soc., 2016
272016
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair
R Shkhyan, B Van Handel, J Bogdanov, S Lee, Y Yu, M Scheinberg, ...
Annals of the Rheumatic Diseases 77 (5), 760-769, 2018
202018
Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases
MP Alam, OM Khdour, PM Arce, Y Chen, B Roy, WG Johnson, S Dey, ...
Bioorganic & medicinal chemistry 22 (17), 4935-4947, 2014
192014
A short DNA sequence confers strong bleomycin binding to hairpin DNAs
C Tang, A Paul, MP Alam, B Roy, WD Wilson, SM Hecht
Journal of the American Chemical Society 136 (39), 13715-13726, 2014
162014
C-O bond formation in a microfluidic reactor: high yield SNAr substitution of heteroaryl chlorides
MP Alam, B Jagodzinska, J Campagna, P Spilman, V John
Tetrahedron Letters 57 (19), 2059-2062, 2016
152016
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2
T Bilousova, C Elias, E Miyoshi, MP Alam, C Zhu, J Campagna, K Vadivel, ...
Biochemical and biophysical research communications 499 (4), 751-757, 2018
122018
DNA methylation reduces binding and cleavage by bleomycin
B Roy, C Tang, MP Alam, SM Hecht
Biochemistry 53 (38), 6103-6112, 2014
102014
Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability
A Chevalier, MP Alam, OM Khdour, M Schmierer, PM Arce, CD Cripe, ...
Bioorganic & medicinal chemistry 24 (21), 5206-5220, 2016
92016
A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity
MP Alam, T Bilousova, P Spilman, K Vadivel, D Bai, C Elias, D Evseenko, ...
ACS Chemical Neuroscience, 2017
62017
Deformable nanovesicles synthesized through an adaptable microfluidic platform for enhanced localized transdermal drug delivery
N Subbiah, J Campagna, P Spilman, MP Alam, S Sharma, A Hokugo, ...
Journal of drug delivery 2017, 2017
42017
Synthesis of fused indolines by interrupted Fischer indolization in a microfluidic reactor
ATH Duong, BJ Simmons, MP Alam, J Campagna, NK Garg, V John
Tetrahedron letters 60 (3), 322-326, 2019
22019
Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
V John, I Nishimura, N Subbiah, J Campagna, PR Spilman, MP Alam
US Patent App. 16/498,301, 2020
2020
Allosteric corticotropin-releasing factor receptor 1 (crfr1) antagonists that decrease p-tau and improve cognition
MP Alam, V John, B Jagodzinska
US Patent App. 16/330,754, 2019
2019
Gp130 modulators
MP Alam, V John, P Spilman, K Vadivel
US Patent App. 16/323,033, 2019
2019
3d-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids
V John, J Campagna, T Bilousova, PR Spilman, PJ Heinzelman, A Hatami, ...
US Patent App. 16/070,249, 2019
2019
Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
V John, I Nishimura, N Subbiah, J Campagna, PR Spilman, MP Alam
US Patent App. 15/774,575, 2018
2018
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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