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haridha shivram
haridha shivram
Genentech
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Year
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
X Deng, MA Garcia-Knight, MM Khalid, V Servellita, C Wang, MK Morris, ...
Cell 184 (13), 3426-3437. e8, 2021
4382021
Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation
X Deng, MA Garcia-Knight, MM Khalid, V Servellita, C Wang, MK Morris, ...
MedRxiv, 2021
2692021
Species-and site-specific genome editing in complex bacterial communities
BE Rubin, S Diamond, BF Cress, A Crits-Christoph, YC Lou, AL Borges, ...
Nature microbiology 7 (1), 34-47, 2022
1542022
Synthetic evolutionary origin of a proofreading reverse transcriptase
JW Ellefson, J Gollihar, R Shroff, H Shivram, VR Iyer, AD Ellington
Science 352 (6293), 1590-1593, 2016
1362016
Controlling and enhancing CRISPR systems
H Shivram, BF Cress, GJ Knott, JA Doudna
Nature chemical biology 17 (1), 10-19, 2021
1332021
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
KE Watters, H Shivram, C Fellmann, RJ Lew, B McMahon, JA Doudna
Proceedings of the National Academy of Sciences 117 (12), 6531-6539, 2020
552020
Bivalent chromatin domains in glioblastoma reveal a subtype-specific signature of glioma stem cells
AW Hall, AM Battenhouse, H Shivram, AR Morris, MC Cowperthwaite, ...
Cancer research 78 (10), 2463-2474, 2018
422018
Chd1 co-localizes with early transcription elongation factors independently of H3K36 methylation and releases stalled RNA polymerase II at introns
D Park, H Shivram, VR Iyer
Epigenetics & chromatin 7, 1-11, 2014
292014
Identification and removal of sequencing artifacts produced by mispriming during reverse transcription in multiple RNA-seq technologies
H Shivram, VR Iyer
Rna 24 (9), 1266-1274, 2018
202018
ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State
A Kosti, L Du, H Shivram, M Qiao, S Burns, JG Garcia, A Pertsemlidis, ...
Molecular Cancer Research 18 (1), 68-78, 2020
172020
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network
H Shivram, SV Le, VR Iyer
Genome Research 29 (2), 184-192, 2019
172019
Targeting novel sites: The amino-terminal DNA binding domain of non-LTR retrotransposons is an adaptable module that is implicated in changing site specificities.
H Shivram, D Cawley, SM Christensen
Mobile Genetic Elements 1 (3), 169-178, 2011
122011
Diverse ATPase proteins in mobilomes constitute a large potential sink for prokaryotic host ATP
H Shim, H Shivram, S Lei, JA Doudna, JF Banfield
Frontiers in Microbiology 12, 691847, 2021
102021
A protein antagonist of activation-induced cytidine deaminase encoded by a complex mouse retrovirus
GB Singh, H Byun, AF Ali, F Medina, D Wylie, H Shivram, AK Nash, ...
MBio 10 (4), 10.1128/mbio. 01678-19, 2019
72019
PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma
H Shivram, SV Le, VR Iyer
Plos one 14 (9), e0222435, 2019
62019
Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19
H Shivram, JA Hackney, CM Rosenberger, A Teterina, A Qamra, ...
bioRxiv, 2022.10. 27.514096, 2022
32022
IgG immune complexes inhibit naïve T cell proliferation and suppress effector function in cytotoxic T cells
W Charab, MG Rosenberger, H Shivram, JM Mirazee, M Donkor, ...
Frontiers in Immunology 12, 713704, 2021
32021
Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19
RN Bauer, A Teterina, H Shivram, J McBride, CM Rosenberger, F Cai, ...
Clinical and Translational Science 16 (6), 1049-1062, 2023
22023
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling
JA Hackney, H Shivram, J Vander Heiden, C Overall, L Orozco, X Gao, ...
Iscience 26 (10), 2023
12023
Transcriptomic and proteomic assessment of tocilizumab response in a randomized controlled trial of patients hospitalized with COVID-19
H Shivram, JA Hackney, CM Rosenberger, A Teterina, A Qamra, ...
Iscience 26 (9), 107597, 2023
12023
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Articles 1–20