| The pharmacology of leishmaniasis R Balaña-Fouce, RM Reguera, JC Cubrıa, D Ordóñez General Pharmacology: The Vascular System 30 (4), 435-443, 1998 | 231 | 1998 |
| Current status on prevention and treatment of canine leishmaniasis RM Reguera, M Moran, Y Perez-Pertejo, C Garcia-Estrada, ... Veterinary parasitology 227, 98-114, 2016 | 144 | 2016 |
| New approaches from nanomedicine for treating leishmaniasis V Gutiérrez, AB Seabra, RM Reguera, J Khandare, M Calderón Chemical Society Reviews 45 (1), 152-168, 2016 | 128 | 2016 |
| Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice RM Reguera, R Balaña-Fouce, M Showalter, S Hickerson, SM Beverley Molecular and biochemical parasitology 165 (1), 48-56, 2009 | 106 | 2009 |
| Polyamine transport in parasites: a potential target for new antiparasitic drug development RM Reguera, BL Tekwani, R Balaña-Fouce Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2005 | 106 | 2005 |
| A novel active DNA topoisomerase I in Leishmania donovani H Villa, ARO Marcos, RM Reguera, R Balana-Fouce, C Garcıa-Estrada, ... Journal of Biological Chemistry 278 (6), 3521-3526, 2003 | 100 | 2003 |
| The transcriptome of Leishmania majorin the axenic promastigote stage: transcript annotation and relative expression levels by RNA-seq A Rastrojo, F Carrasco-Ramiro, D Martín, A Crespillo, RM Reguera, ... BMC genomics 14, 1-13, 2013 | 99 | 2013 |
| Leishmania uses mincle to target an inhibitory ITAM signaling pathway in dendritic cells that dampens adaptive immunity to infection S Iborra, M Martínez-López, FJ Cueto, R Conde-Garrosa, C Del Fresno, ... Immunity 45 (4), 788-801, 2016 | 96 | 2016 |
| Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease … HM Muleme, RM Reguera, A Berard, R Azinwi, P Jia, IB Okwor, ... The Journal of Immunology 183 (12), 8068-8076, 2009 | 91 | 2009 |
| Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis R Balaña-Fouce, E Calvo-Álvarez, R Álvarez-Velilla, CF Prada, ... Molecular and biochemical parasitology 181 (2), 85-93, 2012 | 76 | 2012 |
| Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis E Calvo-Alvarez, K Stamatakis, C Punzon, R Alvarez-Velilla, A Tejeria, ... PLoS neglected tropical diseases 9 (3), e0003666, 2015 | 74 | 2015 |
| Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis D Caridha, B Vesely, K van Bocxlaer, B Arana, CE Mowbray, S Rafati, ... International Journal for Parasitology: Drugs and Drug Resistance 11, 106-117, 2019 | 73 | 2019 |
| DNA topoisomerase I from parasitic protozoa: a potential target for chemotherapy RM Reguera, CM Redondo, RG De Prado, Y Pérez-Pertejo, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1759 (3-4 …, 2006 | 72 | 2006 |
| Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf? RM Reguera, E Calvo-Álvarez, R Álvarez-Velilla, R Balaña-Fouce International Journal for Parasitology: Drugs and Drug Resistance 4 (3), 355-357, 2014 | 65 | 2014 |
| Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery R Balaña-Fouce, R Álvarez-Velilla, C Fernández-Prada, C García-Estrada, ... International Journal for Parasitology: Drugs and Drug Resistance 4 (3), 326-337, 2014 | 62 | 2014 |
| Alterations of the glutathione–redox balance induced by metals in CHO-K1 cells AJ Garcıa-Fernandez, AE Bayoumi, Y Pérez-Pertejo, M Motas, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2002 | 62 | 2002 |
| Targeting atypical trypanosomatid DNA topoisomerase I R Balaña-Fouce, CM Redondo, Y Pérez-Pertejo, R Díaz-González, ... Drug Discovery Today 11 (15-16), 733-740, 2006 | 61 | 2006 |
| Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect CF Prada, R Alvarez-Velilla, R Balana-Fouce, C Prieto, E Calvo-Alvarez, ... Biochemical pharmacology 85 (10), 1433-1440, 2013 | 60 | 2013 |
| Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine … E Calvo-Alvarez, NA Guerrero, R Alvarez-Velilla, CF Prada, JM Requena, ... PLoS neglected tropical diseases 6 (11), e1927, 2012 | 60 | 2012 |
| Indotecan (LMP400) and AM13-55: two novel indenoisoquinolines show potential for treating visceral leishmaniasis R Balaña-Fouce, CF Prada, JM Requena, M Cushman, Y Pommier, ... Antimicrobial agents and chemotherapy 56 (10), 5264-5270, 2012 | 59 | 2012 |
