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Jacqueline S. Dron
Jacqueline S. Dron
Center for Genomic Medicine, Massachusetts General Hospital; Broad Research Institute of MIT and
Dirección de correo verificada de broadinstitute.org
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Improving reporting standards for polygenic scores in risk prediction studies
H Wand, SA Lambert, C Tamburro, MA Iacocca, JW O’Sullivan, C Sillari, ...
Nature 591 (7849), 211-219, 2021
3202021
Polygenic versus monogenic causes of hypercholesterolemia ascertained clinically
J Wang, JS Dron, MR Ban, JF Robinson, AD McIntyre, M Alazzam, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2439-2445, 2016
2152016
Severe hypertriglyceridemia is primarily polygenic
JS Dron, J Wang, H Cao, AD McIntyre, MA Iacocca, JR Menard, ...
Journal of clinical lipidology 13 (1), 80-88, 2019
1802019
Genetics of hypertriglyceridemia
JS Dron, RA Hegele
Frontiers in endocrinology 11, 538521, 2020
1282020
Genetics of triglycerides and the risk of atherosclerosis
JS Dron, RA Hegele
Current atherosclerosis reports 19, 1-10, 2017
1152017
PCSK9: regulation and target for drug development for dyslipidemia
AC Burke, JS Dron, RA Hegele, MW Huff
Annual review of pharmacology and toxicology 57, 223-244, 2017
862017
Targeted next generation sequencing as a tool for precision medicine
M Gulilat, T Lamb, WA Teft, J Wang, JS Dron, JF Robinson, RG Tirona, ...
BMC medical genomics 12, 1-17, 2019
822019
Complexity of mechanisms among human proprotein convertase subtilisin–kexin type 9 variants
JS Dron, RA Hegele
Current opinion in lipidology 28 (2), 161-169, 2017
822017
Use of next-generation sequencing to detect LDLR gene copy number variation in familial hypercholesterolemia
MA Iacocca, J Wang, JS Dron, JF Robinson, AD McIntyre, H Cao, ...
Journal of lipid research 58 (11), 2202-2209, 2017
752017
Erratum to: Genetics of Lipid and Lipoprotein Disorders and Traits
JS Dron, RA Hegele
Current Genetic Medicine Reports 5, 115-115, 2017
68*2017
Polygenic determinants in extremes of high-density lipoprotein cholesterol
JS Dron, J Wang, C Low-Kam, SA Khetarpal, JF Robinson, AD McIntyre, ...
Journal of lipid research 58 (11), 2162-2170, 2017
652017
Six years’ experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias
JS Dron, J Wang, AD McIntyre, MA Iacocca, JF Robinson, MR Ban, H Cao, ...
BMC Medical Genomics 13, 1-15, 2020
632020
Polygenic influences on dyslipidemias
JS Dron, RA Hegele
Current Opinion in Lipidology, 2018
602018
The evolution of genetic-based risk scores for lipids and cardiovascular disease
JS Dron, RA Hegele
Current opinion in lipidology 30 (2), 71-81, 2019
592019
Whole-gene duplication of PCSK9 as a novel genetic mechanism for severe familial hypercholesterolemia
MA Iacocca, J Wang, S Sarkar, JS Dron, T Lagace, AD McIntyre, P Lau, ...
Canadian Journal of Cardiology 34 (10), 1316-1324, 2018
462018
The polygenic nature of mild-to-moderate hypertriglyceridemia
JS Dron, J Wang, AD McIntyre, H Cao, RA Hegele
Journal of clinical lipidology 14 (1), 28-34. e2, 2020
392020
Design and user experience testing of a polygenic score report: a qualitative study of prospective users
DG Brockman, L Petronio, JS Dron, BC Kwon, T Vosburg, L Nip, A Tang, ...
BMC Medical Genomics 14, 1-20, 2021
362021
Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia
JS Dron, J Wang, AJ Berberich, MA Iacocca, H Cao, P Yang, J Knoll, ...
Journal of Lipid Research 59 (8), 1529-1535, 2018
312018
Targeted sequencing reveals expanded genetic diversity of human transfer RNAs
MD Berg, DJ Giguere, JS Dron, JT Lant, J Genereaux, C Liao, J Wang, ...
RNA biology 16 (11), 1574-1585, 2019
292019
Genetics of hypertriglyceridemia and atherosclerosis
PK Gill, JS Dron, RA Hegele
Current opinion in cardiology 36 (3), 264-271, 2021
282021
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Artículos 1–20