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Douglas Vinson Laurents
Douglas Vinson Laurents
Senior Staff Scientist, "Rocasolano" Institute of Physical Chemistry, Spanish National Research
Correu electrònic verificat a iqfr.csic.es
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pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1
CN Pace, DV Laurents, JA Thomson
Biochemistry 29 (10), 2564-2572, 1990
4451990
The cadherin cytoplasmic domain is unstructured in the absence of β-catenin: a possible mechanism for regulating cadherin turnover
AH Huber, DB Stewart, DV Laurents, WJ Nelson, WI Weis
Journal of Biological Chemistry 276 (15), 12301-12309, 2001
3602001
A new method for determining the heat capacity change for protein folding
CN Pace, DV Laurents
Biochemistry 28 (6), 2520-2525, 1989
2641989
Structural similarity of DNA-binding domains of bacteriophage repressors and the globin core
S Subbiah, DV Laurents, M Levitt
Current Biology 3 (3), 141-148, 1993
2461993
Urea denaturation of barnase: pH dependence and characterization of the unfolded state
CN Pace, DV Laurents, RE Erickson
Biochemistry 31 (10), 2728-2734, 1992
1821992
The TDP‐43 N‐terminal domain structure at high resolution
M Mompeán, V Romano, D Pantoja‐Uceda, C Stuani, FE Baralle, ...
The FEBS journal 283 (7), 1242-1260, 2016
1432016
Charge–charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI= 3.5) and a basic variant (pI= 10.2)
DV Laurents, BMP Huyghues-Despointes, M Bruix, RL Thurlkill, D Schell, ...
Journal of molecular biology 325 (5), 1077-1092, 2003
1312003
Structural characterization of the minimal segment of TDP-43 competent for aggregation
M Mompeán, E Buratti, C Guarnaccia, RMM Brito, A Chakrabartty, ...
Archives of biochemistry and biophysics 545, 53-62, 2014
852014
Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions
M Mompeán, V Romano, D Pantoja-Uceda, C Stuani, FE Baralle, E Buratti, ...
Journal of Biological Chemistry 292 (28), 11992-12006, 2017
812017
Molecular basis of Orb2 amyloidogenesis and blockade of memory consolidation
R Hervas, L Li, A Majumdar, MDC Fernandez-Ramirez, JR Unruh, ...
PLoS biology 14 (1), e1002361, 2016
812016
Characterization of the unfolding pathway of hen egg white lysozyme
DV Laurents, RL Baldwin
Biochemistry 36 (6), 1496-1504, 1997
791997
Structural evidence of amyloid fibril formation in the putative aggregation domain of TDP-43
M Mompeán, R Hervás, Y Xu, TH Tran, C Guarnaccia, E Buratti, F Baralle, ...
The journal of physical chemistry letters 6 (13), 2608-2615, 2015
782015
Common features at the start of the neurodegeneration cascade
R Hervas, J Oroz, A Galera-Prat, O Goni, A Valbuena, AM Vera, ...
PLoS biology 10 (5), e1001335, 2012
762012
Protein folding: matching theory and experiment
DV Laurents, RL Baldwin
Biophysical journal 75 (1), 428-434, 1998
761998
NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping
JP Lopez-Alonso, M Bruix, J Font, M Ribo, M Vilanova, MA Jimenez, ...
Journal of the American Chemical Society 132 (5), 1621-1630, 2010
712010
Charge substitution shows that repulsive electrostatic interactions impede the oligomerization of Alzheimer amyloid peptides
M Guo, PM Gorman, M Rico, A Chakrabartty, DV Laurents
FEBS letters 579 (17), 3574-3578, 2005
652005
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and …
G Gotte, DV Laurents, M Libonati
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (1), 44-54, 2006
532006
Alzheimer's Aβ40 studied by NMR at low pH reveals that sodium 4, 4-dimethyl-4-silapentane-1-sulfonate (DSS) binds and promotes β-ball oligomerization
DV Laurents, PM Gorman, M Guo, M Rico, A Chakrabartty, M Bruix
Journal of Biological Chemistry 280 (5), 3675-3685, 2005
532005
Different protein sequences can give rise to highly similar folds through different stabilizing interactions
DV Laurents, S Subbiah, M Levitt
Protein Science 3 (11), 1938-1944, 1994
531994
Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity
JP Lopez-Alonso, F Diez-Garcia, J Font, M Ribó, M Vilanova, JM Scholtz, ...
Bioconjugate chemistry 20 (8), 1459-1473, 2009
492009
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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