| Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases VA Risso, JA Gavira, DF Mejia-Carmona, EA Gaucher, JM Sanchez-Ruiz Journal of the American Chemical Society 135 (8), 2899-2902, 2013 | 289 | 2013 |
| Conformational dynamics and enzyme evolution D Petrović, VA Risso, SCL Kamerlin, JM Sanchez-Ruiz Journal of the Royal Society Interface 15 (144), 20180330, 2018 | 167 | 2018 |
| Evolution of conformational dynamics determines the conversion of a promiscuous generalist into a specialist enzyme T Zou, VA Risso, JA Gavira, JM Sanchez-Ruiz, SB Ozkan Molecular biology and evolution 32 (1), 132-143, 2015 | 146 | 2015 |
| Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history VA Risso, F Manssour-Triedo, A Delgado-Delgado, R Arco, ... Molecular biology and evolution 32 (2), 440-455, 2015 | 94 | 2015 |
| Cooperativity and flexibility in enzyme evolution A Pabis, VA Risso, JM Sanchez-Ruiz, SCL Kamerlin Current opinion in structural biology 48, 83-92, 2018 | 83 | 2018 |
| De novo active sites for resurrected Precambrian enzymes VA Risso, S Martinez-Rodriguez, AM Candel, DM Krüger, ... Nature Communications 8 (1), 16113, 2017 | 74 | 2017 |
| Biotechnological and protein-engineering implications of ancestral protein resurrection VA Risso, JM Sanchez-Ruiz, SB Ozkan Current opinion in structural biology 51, 106-115, 2018 | 71 | 2018 |
| Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins VA Risso, JA Gavira, EA Gaucher, JM Sanchez‐Ruiz Proteins: Structure, Function, and Bioinformatics 82 (6), 887-896, 2014 | 69 | 2014 |
| Manipulating conformational dynamics to repurpose ancient proteins for modern catalytic functions JM Gardner, M Biler, VA Risso, JM Sanchez-Ruiz, SCL Kamerlin ACS Catalysis 10 (9), 4863-4870, 2020 | 52 | 2020 |
| Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity T Modi, VA Risso, S Martinez-Rodriguez, JA Gavira, MD Mebrat, ... Nature communications 12 (1), 1852, 2021 | 39 | 2021 |
| Thermostable and promiscuous Precambrian proteins VA Risso, JA Gavira Gallardo, JM Sánchez Ruiz WILEY, 2014 | 38 | 2014 |
| Radiation synthesis of seroalbumin nanoparticles SLS Espinoza, ML Sánchez, V Risso, EE Smolko, M Grasselli Radiation Physics and Chemistry 81 (9), 1417-1421, 2012 | 37 | 2012 |
| Effects of serine-to-cysteine mutations on β-lactamase folding J Santos, VA Risso, MP Sica, MR Ermácora Biophysical journal 93 (5), 1707-1718, 2007 | 36 | 2007 |
| Enhancing a de novo enzyme activity by computationally-focused ultra-low-throughput screening VA Risso, A Romero-Rivera, LI Gutierrez-Rus, M Ortega-Muñoz, ... Chemical Science 11 (24), 6134-6148, 2020 | 31 | 2020 |
| Enhancing a de novo enzyme activity by computationally-focused ultra-low-throughput screening VA Risso, A Romero-Rivera, LI Gutierrez-Rus, M Ortega-Muñoz, ... Chemical Science 11 (24), 6134-6148, 2020 | 31 | 2020 |
| Engineering ancestral protein hyperstability ML Romero-Romero, VA Risso, S Martinez-Rodriguez, B Ibarra-Molero, ... Biochemical Journal 473 (20), 3611-3620, 2016 | 31 | 2016 |
| Directed -in vitro- evolution of Precambrian and extant Rubiscos BJ Gomez-Fernandez, E Garcia-Ruiz, J Martin-Diaz, P Gomez de Santos, ... Scientific Reports 8 (1), 5532, 2018 | 29 | 2018 |
| Mapping the distribution of conformational information throughout a protein sequence LG Gebhard, VA Risso, J Santos, RG Ferreyra, ME Noguera, ... Journal of molecular biology 358 (1), 280-288, 2006 | 28 | 2006 |
| Ancestral resurrection and directed evolution of fungal mesozoic laccases BJ Gomez-Fernandez, VA Risso, A Rueda, JM Sanchez-Ruiz, M Alcalde Applied and Environmental Microbiology 86 (14), e00778-20, 2020 | 27 | 2020 |
| Consensus design of an evolved high-redox potential laccase BJ Gomez-Fernandez, VA Risso, JM Sanchez-Ruiz, M Alcalde Frontiers in Bioengineering and Biotechnology 8, 354, 2020 | 24 | 2020 |
