Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13254* | 2016 |
Lassa virus entry requires a trigger-induced receptor switch LT Jae, M Raaben, AS Herbert, AI Kuehne, AS Wirchnianski, TK Soh, ... Science 344 (6191), 1506-1510, 2014 | 293 | 2014 |
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy K Bartsch, K Knittler, C Borowski, S Rudnik, M Damme, K Aden, ... Human molecular genetics 26 (20), 3960-3972, 2017 | 208 | 2017 |
Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis JK Götzl, K Mori, M Damme, K Fellerer, S Tahirovic, G Kleinberger, ... Acta neuropathologica 127 (6), 845-860, 2014 | 200 | 2014 |
In vivo evidence for lysosome depletion and impaired autophagic clearance in hereditary spastic paraplegia type SPG11 RE Varga, M Khundadze, M Damme, S Nietzsche, B Hoffmann, T Stauber, ... PLoS genetics 11 (8), e1005454, 2015 | 130 | 2015 |
Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo S Beel, M Moisse, M Damme, L De Muynck, W Robberecht, ... Human molecular genetics 26 (15), 2850-2863, 2017 | 125 | 2017 |
Autophagy in neuronal cells: general principles and physiological and pathological functions M Damme, T Suntio, P Saftig, EL Eskelinen Acta neuropathologica 129 (3), 337-362, 2015 | 112 | 2015 |
Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome R De Pace, M Skirzewski, M Damme, R Mattera, J Mercurio, AM Foster, ... PLoS genetics 14 (4), e1007363, 2018 | 100 | 2018 |
Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice B Kowalewski, WC Lamanna, R Lawrence, M Damme, S Stroobants, ... Proceedings of the National Academy of Sciences 109 (26), 10310-10315, 2012 | 95 | 2012 |
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing AL Gavin, D Huang, C Huber, A Mårtensson, V Tardif, PD Skog, TR Blane, ... Nature immunology 19 (9), 942-953, 2018 | 93 | 2018 |
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis ARA Marques, A Di Spiezio, N Thießen, L Schmidt, J Grötzinger, ... Autophagy 16 (5), 811-825, 2020 | 92 | 2020 |
Lysosomal dysfunction causes neurodegeneration in mucolipidosis II ‘knock-in’mice K Kollmann, M Damme, S Markmann, W Morelle, M Schweizer, ... Brain 135 (9), 2661-2675, 2012 | 91 | 2012 |
Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease P Lüningschrör, B Binotti, B Dombert, P Heimann, A Perez-Lara, C Slotta, ... Nature communications 8 (1), 678, 2017 | 73 | 2017 |
Mannose 6-dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5 G Makrypidi, M Damme, S Müller-Loennies, M Trusch, B Schmidt, ... Molecular and cellular biology, MCB. 06195-11, 2011 | 62 | 2011 |
Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease M Damme, L Brandenstein, S Fehr, W Jankowiak, U Bartsch, M Schweizer, ... Neurobiology of disease 65, 12-24, 2014 | 57 | 2014 |
A homozygous founder missense variant in arylsulfatase G abolishes its enzymatic activity causing atypical Usher syndrome in humans S Khateb, B Kowalewski, N Bedoni, M Damme, N Pollack, A Saada, ... Genetics in Medicine, 2018 | 55 | 2018 |
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 55* | 2016 |
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons P Lüningschrör, G Werner, S Stroobants, S Kakuta, B Dombert, D Sinske, ... Cell Reports 30 (10), 3506-3519. e6, 2020 | 44 | 2020 |
Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks AT Reinicke, K Laban, M Sachs, V Kraus, M Walden, M Damme, W Sachs, ... Proceedings of the National Academy of Sciences 116 (16), 7963-7972, 2019 | 41 | 2019 |
Mannose 6‐phosphate‐independent Lysosomal Sorting of LIMP‐2 J Blanz, F Zunke, S Markmann, M Damme, T Braulke, P Saftig, ... Traffic 16 (10), 1127-1136, 2015 | 39 | 2015 |